2,280 research outputs found
Carlo Barone (1955–2022)
No full textCarlo Barone (1955–2022) was a pioneering performer, researcher, and educator in the nineteenth-century performing practice of the guitar. In this tribute, his friend and collaborator Adrian Walter describes Barone\u27s career
Appunti in tema di affidamento fiduciario successorio, in onore e memoria di Carlo Maria Barone
No full textScrivere di cose giuridiche: l'attualità del contributo di Carlo Maria Barone
No full textUna riflessione intorno allo stato dell'informazione giuridica e un tributo a uno studioso, non accademico, di grandissima levatura
Role of chemotherapy for advanced/recurrent gastric cancer: an individual-patient-data meta-analysis
No full textRole of chemotherapy for advanced/recurrent gastric cancer: an individual-patient-data meta-analysis.
GASTRIC (Global Advanced/Adjuvant Stomach Tumor Research International Collaboration) Group1, Oba K, Paoletti X, Bang YJ, Bleiberg H, Burzykowski T, Fuse N, Michiels S, Morita S, Ohashi Y, Pignon JP, Rougier P, Sakamoto J, Sargent D, Sasako M, Shitara K, Tsuburaya A, Van Cutsem E, Buyse M.
Collaborators (54)
Buyse M, Michiels S, Oba K, Paoletti X, Rougier P, Yamamoto S, Nakamura K, Bang YJ, Bleiberg H, Burzykowski T, Buyse M, Delbaldo C, Michiels S, Morita S, Oba K, Ohashi Y, Paoletti X, Pignon JP, Rougier P, Sakamoto J, Sargent D, Sasako M, Van Cutsem E, Ajani J, Boku N, Barone C, Borner M, Bouche O, Bugat R, Coombes C, Cullinan S, Dank M, Douglass H, Fuse N, Glimelius B, Hawkins R, Kanzler S, Koizumi W, Kim TW, Lordick F, Moehler M, Nio Y, Ohtsu A, Pozzo C, Reichardt P, Roth A, Schumacher C, Shitara K, Thuss-Patience P, Tsuburaya A, Van Cutsem E, Vanhoefer U, Wils J, Yamamura Y.
Author information
Abstract
We conducted an individual-patient-data meta-analysis of the efficacy of chemotherapy on overall survival (OS) and progression-free survival (PFS) in advanced/recurrent gastric cancer (AGC). Our primary research question was whether the experimental arms of the trials included in the meta-analysis showed a benefit as compared with their corresponding control arms. MEDLINE (up to 2010), Cochrane Central Register of Controlled Trials, National Institutes of Health (NIH) trial registry and proceedings of major oncologic and gastrointestinal cancer meetings were searched. Randomised controlled trials for AGC closed to patient accrual before the end of 2006 were eligible. As of December 2010, individual patient data were available from 22 trials (4245 patients, representing 47% of the targeted data) of 55 eligible trials. The overall comparison of experimental arms with the corresponding control arms showed statistically significant differences in terms of both OS and PFS. Hazard ratio was 0.88 (95% confidence interval 0.82-0.94, P<0.0001) for OS and 0.81 (0.76-0.88, P<0.0001) for PFS. The results of the sub-analysis of adding a given chemotherapeutic agent to any chemotherapy confirm the results of the overall analysis, with a hazard reduction of 11% for OS (P<0.01) and 26% for PFS (P<0.0001). This meta-analysis of individual patient data shows that the additions of experimental chemotherapeutic agents to pre-existing control or standard regimens have produced a modest improvement in OS and PFS. Median survival remained below 1 year for all investigated chemotherapy regimens and none emerged as a clear standard
Is university education worth the investment? The expectations of upper secondary school seniors and the role of family background
No full textThis study assesses students’ expectations about the profitability of the investment in university education. We consider Italy as a test case and provide fresh high-quality data on students’ expectations concerning the costs, economic returns and chances of success of this investment. These are compared with data on the corresponding actual values. We find that the estimates provided by upper secondary school seniors are highly inaccurate, highly uncertain and systematically biased. Students overestimate the returns to university degrees, while they are over-pessimistic regarding university costs and drop-out risks. These results confirm previous studies on perceived university costs, but they challenge the dominant view that students can realistically forecast graduate earnings. We trace this discrepancy to two methodological shortcomings of several previous studies on expected graduate earnings. Moreover, we find that information barriers are not equally distributed among social groups. High-status students overestimate the economic returns to university more, and they are more optimistic regarding their chances of success in Higher Education, even after allowing for their higher objective returns and chances of success. Our interpretation of the importance of information barriers focuses on the interaction between cognitive biases and institutional constraints
Relative risk aversion models: how plausible are their assumptions ? Review of top-cited articles
No full textEN: This document presents the results of a systematic review of top-cited articles on the Breen-Goldthorpe model of educational decisions.
More specifically, we coded how each article presents and assesses the two key assumptions of this model, the Downward Mobility Assumption and the Risky Choice Asssumption.
FR : Ce document présente les résultats d'une revue systématique des articles les plus cités dans le modèle décisionnel de Breen-Goldthorpe en matière d'éducation.
Plus précisément, nous avons consigné comment chaque article présente et évalue les deux hypothèses essentielles : l'hypothèse de mobilité descendante et l'hypothèse de choix risqué
Vivere il diritto. Studi in onore di Carlo Maria Barone
No full textRaccolta di scritti (31) dedicati alla memoria di Carlo Maria Baron
Giardini e paesaggi di Cosimo
No full textSaggio sul ruolo dei temi del giardino e del paesaggio nell'opera di Italo Calvino, con particolare riferimento a "Il Barone Rampante"
Is university education worth the investment? The expectations of upper secondary school seniors and the role of family background
No full textThis study assesses students’ expectations about the profitability of the investment in university education. We consider Italy as a test case and provide fresh high-quality data on students’ expectations concerning the costs, economic returns and chances of success of this investment. These are compared with data on the corresponding actual values. We find that the estimates provided by upper secondary school seniors are highly inaccurate, highly uncertain and systematically biased. Students overestimate the returns to university degrees, while they are over-pessimistic regarding university costs and drop-out risks. These results confirm previous studies on perceived university costs, but they challenge the dominant view that students can realistically forecast graduate earnings. We trace this discrepancy to two methodological shortcomings of several previous studies on expected graduate earnings. Moreover, we find that information barriers are not equally distributed among social groups. High-status students overestimate the economic returns to university more, and they are more optimistic regarding their chances of success in Higher Education, even after allowing for their higher objective returns and chances of success. Our interpretation of the importance of information barriers focuses on the interaction between cognitive biases and institutional constraints
<b>Supplemental Material – Supplemental Material for Are upper-secondary track decisions risky? Evidence from Sweden on the assumptions of risk-aversion models</b>
No full textSupplemental Material, Supplemental Material for Are upper-secondary track decisions risky? Evidence from Sweden on the assumptions of risk-aversion models by Anton B. Andersson, Carlo Barone,and Martin Hällsten in Rationality and Society.</p
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