179,440 research outputs found

    European Integration and Knowledge Flows across European Regions

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    Cappelli R. and Montobbio F. European integration and knowledge flows across European regions, Regional Studies. Using data on inventor citations and inventor collaborations, changes in geographical patterns of knowledge flows between European regions during the period 1981–2000 are analysed. It is shown that inventor collaborations become less geographically localized, while inventor citations become more localized. The European integration process has a significant effect on reducing barriers to knowledge flows between new and old European Union members. For inventor citations, this effect relates only to the European Union enlargement of 1995 and is confined to knowledge flows from Austria, Finland and Sweden to old European Union members

    Pre-Modern State-Building in Post-Soviet Russia

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    'Transitology', or the study of transitions from communist rule to what was expected to be applications of Western-style democracy, suffered from fatal misapprehensions that ensured its failure to explain, predict or effectively guide the developments that took place during the 1990s. In particular, it lacked a historical dimension and it misunderstood the proper function of the state in establishing a political regime. Stateness, or state strength, is an essential variable and the acquisition of that quality is vital. It involves two fundamental aspects; asserting the state’s political autonomy from the social context, i.e. its ability to formulate interests of its own, and establishing its governmental capacity, or the state’s abilIty to achieve its goals. Historical analogies with 'feudal' and 'absolutist' political regimes are helpful in explaining the task that confronted Putin on assuming office as the designated heir of the chaotic legacy of Boris Yeltsin. The assertion of state power under Putin's leadership should not be seen as an authoritarian reversal that followed a democratic wave but is comparable with the pre-modem process of state-building that took centuries following the decline of feudalism in Western Europe. Whether the Russian state will strengthen and become an institutionalized democracy following the European sequence remains unclear; but even democratic leaders need a government able 'to control the governed'

    MANUALE DI DIAGNOSTICA PER IMMAGINI PER IL CORSO DI LAUREA IN MEDICINA E CHIRURGIA. DIAGNOSTICA PER IMMAGINI DEL FEGATO, DELLA MILZA, DEL PERITONEO E MESENTERE. 2°edizione CAPITOLO 8 - 10 - 13

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    1) DIAGNOSTICA PER IMMAGINI DEL FEGATO di R. Golfieri, M. Renzulli, A. Cappelli (Capitolo 8 pag.157-218): Nello studio della patologia epatica hanno un ruolo essenziale l'ecografia (US) completata da eco-color Doppler (ECD) e da mdc (ecocontrastografia), la TC, la RM e la colangio-RM. La scintigrafia e l'angiografia hanno un ruolo in settori ben definiti. 2) DIAGNOSTICA PER IMMAGINI DELLA MILZA di R. Golfieri, A. Cappelli (Capitolo 10 pag. 245-270): II compito principale delle metodiche di imaging è quello di: determinare il volume splenico, individuare eventuali lesioni focali, fornire una definizione nosografia delle splenomegalie, associate o meno a ipersplenismo e riconoscere la rottura della milza secondo i gradi di gravità 3) DIAGNOSTICA PER IMMAGINI DEL PERITONEO E MESENTERE di R. Golfieri, V. Orsini, B. Corcioni (Capitolo 13 pag. 319-2342

    Foreword

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    Breve prefazione in inglese all'opera che include contributi in diverse lingue (francese, tedesco, spagnolo e inglese

    Fingerprint verification competition 2006

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    The interest in fingerprint-based biometric systems has constantly grown in recent years and considerable efforts have been focused by both academia and industry on the development of new algorithms for fingerprint recognition. Raffaele Cappelli, Matteo Ferrara, Annalisa Franco and Davide Maltoni of the Biometric System Laboratory at the University of Bologna explain the findings of the Fingerprint Verification Competition 2006

    Logistica e trasporti per i sistemi produttivi locali: metodi e modelli applicati alla realtà produttiva del nord est padano

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    La memoria sintetizza i risultati del progetto PRIN 2002 coordinato a livello nazionale dal prof. Cappelli. Il tema e gli obiettivi del progetto possono essere definiti come ricerca delle basi di conoscenza analitiche, degli strumenti di analisi, dei modelli di interpretazione e simulazione, dell’efficacia delle misure da attuare per la realizzazione di un sistema logistico integrato produzione - trasporti al servizio, in particolare, dei distretti produttivi regionali. Altro elemento di interesse è rappresentato dalla necessità di procedere con una procedura integrata che analizzi le necessità e l'organizzazione dei sistemi produttivi locali con quanto può offrire l'ingegneria dei trasporti, laddove generalmente i due aspetti: logistica della produzione e logistica dei trasporti vengono esaminati in forma disgiunta (Leitham S., McQuaid R.W., Nelson J.D. 2000). L’esame interdisciplinare dei problemi della mobilità merci, degli strumenti di “gestione della domanda” tipici di una logistica avanzata richiedono, infatti (Cappelli A., aprile 2002): - La conoscenza dettagliata dei sistemi di produzione integrata e di commercializzazione dei prodotti; - La conoscenza dettagliata delle prestazioni del sistema integrato plurimodale dei trasporti (attuale e previsto); - La conoscenza dettagliata delle funzioni di scelta ed in particolare la “funzione costo percepito del trasporto” e dei modelli matematici di interpretazione e riproduzione dei fenomeni; - La conoscenza dettagliata delle esternalità connesse all’attuale organizzazione dell’offerta di servizi logistici e di trasporto tradizionale. Lo studio è stato pertanto articolato in un esame generale, preliminare, di alcuni sistemi produttivi regionali e delle loro relazioni con il trasporto (organizzazione, prestazioni, costi diretti ed indiretti) e quindi affronta in forma approfondita l’esame e le proposte per alcune catene logistiche tipiche dell'organizzazione produttiva del Veneto e dell'Emilia Romagna

    Fast and Accurate Fingerprint Indexing based on Ridge Orientation and Frequency

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    This paper describes a new fingerprint indexing approach based on vector and scalar features, obtained from ridge-line orientations and frequencies. A carefully designed set of features and ad-hoc score measures allow the proposed indexing algorithm to be extremely effective and efficient, as confirmed by the results of extensive experiments. The new method markedly outperforms competing state-of-the-art techniques over six publicly available datasets; furthermore, it can scale to large databases without losing accuracy: on a standard PC, a search over one million fingerprints takes less than one second

    Tre based methods theory and applications in R

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    Il seminario è stato tenuto nell’ambito del corso “Metodologie Avanzate e nuove tecnologie per il marketing” attivato presso un CdL Magistrale ed ha introdotto gli studenti alla classificazione e regressione albero da un punto vista metodologico ed anche applicativo essendosi tenutosi in aula multimediale quindi gli studenti hanno potuto elaborare gli script in R e commentare i risultati delle applicazioni in modo partecipativo

    Transarterial radioembolization using yttrium-90 microspheres in the treatment of hepatocellular carcinoma: a review on clinical utility and developments

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    Alberta Cappelli,1 Cinzia Pettinato,2 Rita Golfieri1 1Radiology Unit, 2Medical Physics Unit, Department of Medical and Surgical Sciences, Alma Mater Studiorum – University of Bologna, S Orsola-Malpighi Hospital, Bologna, Italy Abstract: A selective intra-arterial liver injection using yttrium-90-loaded microspheres as sources for internal radiation therapy is a form of transarterial radioembolization (TARE). Current data from the literature suggest that TARE is effective in hepatocellular carcinoma (HCC) and is associated with a low rate of adverse events; however, they are all based on retrospective series or non-controlled prospective studies, since randomized controlled trials comparing the other liver-directed therapies for intermediate and locally advanced stages HCC are still ongoing. The available data show that TARE provides similar or even better survival rates. TARE is very well tolerated and has a low rate of complications; these complications do not result from the embolic effects but mainly from the unintended irradiation to non-target tissue, including the liver parenchyma. The complications can be further reduced by accurate patient selection and a strict pre-treatment evaluation, including dosimetry and assessment of the vascular anatomy. First-line TARE is best indicated for intermediate-stage patients (according to the Barcelona Clinic Liver Cancer [BCLC] staging classification) who are poor candidates for transarterial chemoembolization or patients having locally advanced disease with segmental or lobar branch portal vein thrombosis. Moreover, data are emerging regarding the use of TARE in patients classified slightly above the criteria for liver transplantation with the purpose of downstaging them. TARE can also be applied as a second-line treatment in patients progressing to transarterial chemoembolization or sorafenib; a large number of Phase II/III trials are in progress in order to evaluate the best association with systemic therapies. Given the complexity of a correct treatment algorithm for potential TARE candidates and the need for clinical guidance, a comprehensive review was carried out analyzing both the best selection criteria of patients who really benefit from TARE and the new advances of this therapy which add significant value to the therapeutic weaponry against HCC. Keywords: radioembolization, yttrium-90, hepatocellular carcinom
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