1,721,048 research outputs found
A framework for data-driven adaptive GUI generation based on DICOM
No full textComputer applications for diagnostic medical imaging provide generally a wide range of tools to support physicians in their daily diagnosis activities. Unfortunately, some functionalities are specialized for specific diseases or imaging modalities, while other ones are useless for the images under investigation. Nevertheless, the corresponding Graphical User Interface (GUI) widgets are still present on the screen reducing the image visualization area. As a consequence, the physician may be affected by cognitive overload and visual stress causing a degradation of performances, mainly due to unuseful widgets. In clinical environments, a GUI must represent a sequence of steps for image investigation following a well-defined workflow. This paper proposes a software framework aimed at addressing the issues outlined before. Specifically, we designed a DICOM based mechanism of data-driven GUI generation, referring to the examined body part and imaging modality as well as to the medical image analysis task to perform. In this way, the self-configuring GUI is generated on-the-fly, so that just specific functionalities are active according to the current clinical scenario. Such a solution provides also a tight integration with the DICOM standard, which considers various aspects of the technology in medicine but does not address GUI specification issues. The proposed workflow is designed for diagnostic workstations with a local file system on an interchange media acting inside or outside the hospital ward. Accordingly, the DICOMDIR conceptual data model, defined by a hierarchical structure, is exploited and extended to include the GUI information thanks to a new Information Object Module (IOM), which reuses the DICOM information model. The proposed framework exploits the DICOM standard representing an enabling technology for an auto-consistent solution in medical diagnostic applications. In this paper we present a detailed description of the framework, its software design, and a proof-of-concept implementation as a suitable plug-in of the OsiriX imaging software
Messa a punto di un protocollo sperimentale per la ricerca di Enterovirus in sedimenti marini
No full textIn riferimento al Decreto Ministeriale del 24/01/1996, il controllo dei fondali marini utilizzati per il ripascimento dei litorali, costituisce un passo importante per la valutazione della salubrità dell’ambiente marino e dei prodotti ittici da allevamento, con particolare riferimento alla coltivazione di molluschi eduli lamellibranchi. Diversi studi, infatti, hanno dimostrato come i sedimenti, per le loro caratteristiche chimico-fisiche, rappresentano dei “serbatoi” di agenti microbici di varia natura che, da qui possono essere risospesi nelle acque, compromettendo la salubrità dell’ambiente. Poiché i molluschi eduli lamellibranchi sono organismi filtratori e trattengono agenti patogeni causa di malattie nell’uomo, è importante conoscere il livello di contaminazione microbiologica dell’ambiente in cui essi sono allevati. In quest’ottica, l’analisi virologica di campioni ambientali, assume una particolare importanza, in considerazione di alcune caratteristiche peculiari dei virus, tra cui l’elevata resistenza nell’ambiente, la bassa carica infettante, nonché l’elevata variabilità genetica che pone il rischio di impreviste emergenze sanitarie. I controlli delle acque di mare e dei molluschi sono regolamentati rispettivamente dal D.P.R. 470/86 e dal D. Leg 530/92, i quali prevedono la ricerca di batteri indicatori di contaminazione fecale (Coliformi, Streptococchi e Salmonella) definendone i limiti quantitativi e i protocolli operativi e lasciando, invece, facoltativa le ricerca di Enterovirus. Pertanto, in mancanza di protocolli standardizzati per la ricerca di virus, un utile approccio al problema è rappresentato dalla ottimizzazione di metodi diagnostici sensibili, in grado di rilevare tali patogeni nei campioni di origine ambientale. Gli A.A., nel presente lavoro, hanno messo a punto una metodica di estrazione e concentrazione di agenti virali dai sedimenti marini, attraverso una prova di contaminazione sperimentale di tale matrice con il virus dell’Epatite A (HAV). La ricerca del virus nei campioni pretrattati è stata eseguita attraverso l’uso di una specifica “seminested” RT-PCR seguita dall’isolamento in colture cellulari permissive FRhK-4 (foetal rhesus monkey kidney). Il protocollo ottimizzato, è stato adottato successivamente, per analizzare 162 campioni di sedimenti marini, prelevati in aree costiere della Sicilia occidentale ed orientale in cui sono presenti allevamenti di molluschi. In particolare, i sedimenti sono stati analizzati per la ricerca di Enterovirus ed HAV attraverso due specifiche RT-PCR ed attraverso tecniche di isolamento virale, rispettivamente in BGM (buffalo green monkey ) e FRhK4.The discharge of domestic sewage effluent bearing pathogenic enteric viruses into estuaries and coastal waters, has been demonstrated to pose a public health risk. Enteric virus are often discovered in water for human use and in fish origin foods, as shellfish. In consideration of the importance of the sea for Sicilian economy, it is significant to consider as a public health problems, those related to the fishing and fish culture. At moment, Italian rules for sea water, shellfish and sediments controls (D.P.R. 470/82, D. Leg 530/92 and D.M. del 24/01/1996 ) establish protocols only for bacteriological analysis, to research some fecal contamination indicators as Enterococcus, Streptococcus and Salmonella. Virological analysis of marine sediments is very important, because they represent a “reservoir” of viruses and pose a potential risk for water contamination. Therefore, it is important to optimize an operative and applicable diagnostic tool to control and warrant environmental and fishing yield health (Total Quality).
In this study, Authors optimize a method to elute and concentrate viruses from marine sediments samples, through an experimental infection of them, with Hepatitis A virus (HAV). The virus detection was performed through a specific “seminested” RT-PCR and an in vitro virus isolation in FRhK-4 cell monolayers. Then, 162 marine sediments samples, taken out from various Sicilian coast areas, were analyzed using the described protocol and tested for Enterovirus and HAV assay, using two specific seminested RT-PCR and cell colture isolation on BGM (buffalo green monkey) and FRhK4 (foetal rhesus monkey kidney)
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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