1,214 research outputs found

    oneChannelGUI: a graphical interface to Bioconductor tools, designed for life scientists who are not familiar with R language

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    OneChannelGUI is an add-on Bioconductor package providing a new set of functions extending the capability of the affylmGUI package. This library provides a graphical interface (GUI) for Bioconductor libraries to be used for quality control, normalization, filtering, statistical validation and data mining for single channel microarrays. Affymetrix 3' expression (IVT) arrays as well as the new whole transcript expression arrays, i.e. gene/exon 1.0 ST, are actually implemented. oneChannelGUI is available for most platforms on which R runs, i.e. Windows and Unix-like machines. © The Author 2007. Published by Oxford University Press. All rights reserved

    GPR and ERT surveys in the Giardino dell’Annunziata in Cammarata (Sicily)

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    A recovery project has recently involved a garden sited in Cammarata (Southern Sicily), known as "Giardino dell'Annunziata" adjacent to the church of the same name (Chiesa dell'Annunziata). In this area, according to the scarce historical sources, there was a Benedictine convent, probably demolished in the eighteenth century. As a diagnostical support some geophysical surveys were carried out in the garden. A 3D geoelectric survey and 36 Ground Penetrating Radar (GPR) profiles were carried out which made it possible to reconstruct the corresponding 3D models of the subsoil. A large resistive anomaly has been detected, which has no match in the 3D GPR model showing only minor surface anomalies. The anomalous area can be due to an original flow route of the river, but it cannot be excluded that it is caused by an artificial channel or even underground environments, subsequently filled with landfill material. Archaeological excavations are planned to better clarify the nature of the anomaly

    Costrutto di acido nucleico, vettore e vaccino a DNA includenti detto costrutto

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    La presente invenzione si riferisce al settore dei vaccini a DNA, in particolare a un costrutto di acido nucleico, preferibilmente clonato all’interno di un vettore plasmidico, utile per l’impiego come vaccino a DNA per il trattamento di patologie tumorali o patologie infiammatorie in un animale, preferibilmente un mammifero, ivi incluso l’essere umano

    «Non tanto per el guadagno quanto per l’onore». Marco Zoppo, the italian courts and the humanists

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    Through a comprehensive speech so far never carried out, this article intends to reconstract the close web of human and professional relations maintain by Marco Ruggeri, known as Lo Zoppo (1432/33 - 1478) with humanists, his contemporary literates and major courts in northen Italy. Zoppo was close to prominent humanists from northen Italy, in the same way of Andrea Mantegna, his main colleague: Felice Feliciano, the antiquarius from Verona, the humanist doctor Giovanni Marcanova, Marcantonio Morosini, the patrician from Venezia, Raffaele Zovenzoni, the poet from Trieste and Giovanni Testa Cillenio, the Petrarcan rhymer, for instance. Those erudites frequentations are attest to letters and appreciative mentions in poems and they influence the matter and the creative modalities of Zoppo's art.The painter from Emilia was often engaged, as illustrator, in eminent tall orders about books and others ornamental works. Marco Zoppo was hightly regarded for his dowers of inventio, that are clearly visible into his ample and various drawings corpus. He was also a worthy exponent of the renovate fascinating for the antique, that captivates an entire generation of padani artists and clients from the second half of XV century

    The developmental effects of media-ideal internalization and self-objectification processes on adolescents’ negative body-feelings, dietary restraint, and binge eating

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    Despite accumulated experimental evidence of the negative effects of exposure to media-idealized images, the degree to which body image, and eating related disturbances are caused by media portrayals of gendered beauty ideals remains controversial. On the basis of the most up-to-date meta-analysis of experimental studies indicating that media-idealized images have the most harmful and substantial impact on vulnerable individuals regardless of gender (i.e., “internalizers” and “self-objectifiers”), the current longitudinal study examined the direct and mediated links posited in objectification theory among media-ideal internalization, self-objectification, shame and anxiety surrounding the body and appearance, dietary restraint, and binge eating. Data collected from 685 adolescents aged between 14 and 15 at baseline (47 % males), who were interviewed and completed standardized measures annually over a 3-year period, were analyzed using a structural equation modeling approach. Results indicated that media-ideal internalization predicted later thinking and scrutinizing of one’s body from an external observer’s standpoint (or self-objectification), which then predicted later negative emotional experiences related to one’s body and appearance. In turn, these negative emotional experiences predicted subsequent dietary restraint and binge eating, and each of these core features of eating disorders influenced each other. Differences in the strength of these associations across gender were not observed, and all indirect effects were significant. The study provides valuable information about how the cultural values embodied by gendered beauty ideals negatively influence adolescents’ feelings, thoughts and behaviors regarding their own body, and on the complex processes involved in disordered eating. Practical implications are discussed
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