1,756 research outputs found

    Central nervous system metastasis of an intradural malignant peripheral nerve sheath tumour in a dog

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    An 8-year-old French Bulldog was presented with a nonambulatory tetraparesis. Magnetic Resonance showed an intradurally located mass at the level of the right second cervical nerve root. The mass was surgically removed and the dog was ambulatory within four days. A ten-month post-surgical imaging follow up revealed a recurrence of the primary mass and another intradural/intramedullary mass at the level of the first thoracic vertebral body. Overall histological features were suggestive of malignant peripheral nerve sheath tumour for both masses. Immunohistochemistry was found weakly but diffusely positive for S-100 and NSE for both masses. A diagnosis of primary malignant peripheral nerve sheath tumour for the cervical mass and of metastasis for the thoracic mass was made, possibly disseminated via the subarachnoidal space. To our knowledge, central nervous system metastasis of malignant peripheral nerve sheath tumours have not previously been reported in dogs. The clinician should be aware that these tumours, albeit rarely, can metastasize to the central nervous system

    Recuerdos de Massimo.

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    El presente ensayo recuerda la rica relación personal e intelectual entre Massimo Pavarini e Iñaki Rivera Beiras desde que el segundo conoció siendo muy joven a Pavarini. En ese sentido, el trabajo recuerda los inicios de su fecunda relación en la ciudad de Bologna cuando Iñaki Rivera acudía a presentar a Massimo Pavarini los desarrollos de lo que sería su tesis doctoral. Las contribuciones de Pavarini al proceso de aprendizaje de Rivera, en el terreno de una epistemología crítica en la penología contemporánea, son analizados como un homenaje a la memoria y a la obra del autor italiano, tras su fallecimiento en septiembre de 2015.This paper recalls the rich personal and intellectual relationship between Massimo Pavarini and Iñaki Rivera Beiras. In that sense , the work recalls the beginning of his fruitful relationship in the city of Bologna when Iñaki Rivera came to present Massimo Pavarini’ developments in what would be his PhD thesis. Pavarini contributions to the learning process of Rivera, on the ground of a critical epistemology in contemporary penology , are analyzed as a tribute to the memory and to the work of Italian author, after his death in September 2015 .El presente ensayo recuerda la rica relación personal e intelectual entre Massimo Pavarini e Iñaki Rivera Beiras desde que el segundo conoció siendo muy joven a Pavarini. En ese sentido, el trabajo recuerda los inicios de su fecunda relación en la ciudad de Bologna cuando Iñaki Rivera acudía a presentar a Massimo Pavarini los desarrollos de lo que sería su tesis doctoral. Las contribuciones de Pavarini al proceso de aprendizaje de Rivera, en el terreno de una epistemología crítica en la penología contemporánea, son analizados como un homenaje a la memoria y a la obra del autor italiano, tras su fallecimiento en septiembre de 2015

    Predoni a casa nostra e il geografo solidale: Massimo Quaini tra terra e acqua

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    In accordance with the main goals of this collection of essays in honour of Massimo Quaini, the text focuses on a peculiar character of the Ligurian geographer’s sensibility, his attention to landscape protectionresearch activity developed in the context of the humanistic geography. Starting from a personal narrative based on his own reminiscences and neglected memories, the author tries to shed light on the relationships between civil commitment and cultural reflection which characterize environmental sensitivity, bringing together his interests with Quaini’s emotional geographies. Finally, some of Quaini’s everyday practicalities are highlighted as the easiest doorway to improve the cognitive procedures of cultural geography

    Is Felix Salten the author of the Mutzenbacher novel (1906)? Yes and no

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    Josefine Mutzenbacher oder die Geschichte einer Wienerischen Dirne von ihr selbst erzählt, published in Vienna in 1906, represents one of the most fascinating cases of attribution of authorship in German literature. Although Josefine Mutzenbacher is usually attributed to Felix Salten, the author of the world-famous Bambi (1923), the novel’s authorship has never been confirmed, and many other candidates have been named as potential authors. Among them is Arthur Schnitzler, who published Reigen, a cycle of amorous adventures in Viennese society, in 1903. Some scholars, instead, have attributed the novel to such lesser-known writers as Ernst Klein and Willi Handl. The controversy surrounding the authorship of Josefine Mutzenbacher was the starting point for our stylometric analyses, and our results help to answer some unresolved questions in a debate that has lasted for more than 100 years. The analyses were performed using the R package Stylo, which enables an efficient application of Burrows’ Delta and its variants. Focusing on both the entire text and on the final pages, two different types of analysis were carried out: one combines 1200 different stylometric methods to compare the candidate authors Salten, Schnitzler, Bahr, Altenberg, Hofmannsthal, Klein and Handl; the other verifies the attribution using the ‘impostors’ method. The results show that the most probable author is Felix Salten, while none of the candidates could be identified as the author of the final pages, confirming the hypothesis that the text was left unfinished by Salten and completed by an as-yet-unidentified ghost-writer

    Plastid Genotyping Reveals the Uniformity of Cytoplasmic Male Sterile-T Maize Cytoplasms

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    Cytoplasmic male-sterile (CMS) lines in maize (Zea mays) have been classified by their response to specific restorer genes into three categories: cms-C, cms-S, and cms-T. A mitochondrial genome representing each of the CMS cytotypes has been sequenced, and male sterility in the cms-S and cms-T cytotypes is linked to chimeric mitochondrial genes. To identify markers for plastid genotyping, we sequenced the plastid genomes of three fertile maize lines (B37, B73, and A188) and the B37 cms-C, cms-S, and cms-T cytoplasmic substitution lines. We found that the plastid genomes of B37 and B73 lines are identical. Furthermore, the fertile and CMS plastid genomes are conserved, differing only by zero to three single-nucleotide polymorphisms (SNPs) in coding regions and by eight to 22 SNPs and 10 to 21 short insertions/deletions in noncoding regions. To gain insight into the origin and transmission of the cms-T trait, we identified three SNPs unique to the cms-T plastids and tested the three diagnostic SNPs in 27 cms-T lines, representing the HA, I, Q, RS, and T male-sterile cytoplasms. We report that each of the tested 27 cms-T group accessions have the same three diagnostic plastid SNPs, indicating a single origin and maternal cotransmission of the cms-T mitochondria and plastids to the seed progeny. Our data exclude exceptional pollen transmission of organelles or multiple horizontal gene transfer events as the source of the mitochondrial urf13-T (unidentified reading frame encoding 13-kD cms-T protein) gene in the cms-T cytoplasms. Plastid genotyping enables a reassessment of the evolutionary relationships of cytoplasms in cultivated maize.Peer reviewe

    A cidade, de Massimo Cacciari

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    This review presents a summary of the series of seminars presented by Massimo Cacciari at the Centro Sant´Apollinare de Fiesole, transcribed and edited by Tonino Rasuto. The work, entitled The city, brings reflections on what the author understands as the origin of urban configurations, more precisely what he classifies as the post-metropolis, the city-territory, which has its formation linked to the principles of Greek polis and of the Roman civitas. Finally, the author defines the potential of place and the geography of events, based on a methodological path of understanding the phenomena that were able to reframe the meaning of the city for the human being.Apresenta-se nesta resenha, uma síntese da série de seminários apresentados por Massimo Cacciari no Centro Sant´Apollinare de Fiesole, transcrita e editada por Tonino Rasuto. A obra, de título A cidade, traz reflexões acerca do que o autor entende como a origem das configurações urbanas, mais precisamente o que classifica como a pós-metrópole, a cidade-território, que tem sua formação ligada aos princípios da pólis grega e da civitas romana. Por fim, o autor define o potencial de lugar e da geografia de acontecimentos, a partir de um caminho metodológico de entendimentos dos fenômenos que foram capazes de ressignificar o sentido de cidade para o ser humano

    Calcolo di stabilità della cupola del Teatro massimo di Palermo /

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    Mode of access: Internet.Bound in original printed wrappers; inscribed to G. Pini by the author on front wrapper

    Odeporica by Massimo Bontempelli

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    L‘opera si basa sull‘autore Massimo Bontempelli e sulla sua opera Stato di grazia. Date le particolarità che sono state fornite, è stato di grande importanza prestare attenzione al lavoro. L‘autore si distingue per il suo modo di scrivere che, durante il periodo in cui è stato creato, si distingue dagli altri. Pertanto, all'inizio del documento, vengono fornite informazioni di base sull‘autore, sulla sua vita, sulle opere scritte e sulle fasi che ha attraversato fino a raggiungere la fine. Dopo che sono state fornite le informazioni sull‘autore si focalizza sulla letteratura di viaggio in generale per procedere alle caratteristiche dell‘opera bontempelliana appartenente all‘odeporica. La seconda parte della tesi si concentra sull‘opera Stato di grazia e mette in evidenzia i procedimenti narrativi tipici per tutta la produzione letteraria di Massimo Bontempelli. Nella terza parte si interpretano e si mettono in paragone diversi punti di vista presenti in tre capitoli: Italia, Europa e l‘America. Vengono inoltre evidenziate le caratteristiche della letteratura di viaggio nonché alcune peculiarità della poetica bontempelliana.U radu se analizira djelo Stato di grazia talijanskog autora Massima Bontempellija. Autor je to koji u povijesti europske književnosti ostaje zapamćen kao tvorac poetike magičnog realizma. Prvi dio rada donosi prikaz autorove biografije i književnog sazrijevanja podijeljenog u nekoliko faza. Kako navedeno djelo pripada putopisnoj književnosti, jedno je poglavlje posvećeno pokušaju definiranja osnovnih karakteristika putopisne književnosti. Slijedi poglavlje u kojem se polazeći od sadržaja analiziraju pripovjedni postupci koje Bontempelli primjenjuje u navedenom putopisu. U radu se naposlijetku nakon iscrpne interpretacije i usporedbe sličnosti i razlika vidljivih u tri poglavlja naslovljena Italija, Europa i Južna Amerika, upućuje na sve specifičnosti Bontempellijeve putopisne poetike.The paper analyzes the work Stato di grazia by the italian author Massimo Bontempelli. He is an author who is remembered in the history of European literature as the creator of the poetics of the magical realism. The first part of the paper presentrs the author‘s biography and literary maturation divided into several phases. As the mentioned work belongs to travel literature, one chapter is dedicated to the attempt to define the basic characteristics of travel literature. The following is a chapter in which, based on the content, the narrrative procedures that Bontempelli applies in the above travelogue are analyzed. Finally, after an exhaustive interpretation and comparison of the similarities and differences visible in the three chapters entitled Italy, Europe and South America, the paper refers to all the specifics of Bontempelli‘s travel poetics

    Magnetic Resonance Imaging Studies of Postpartum Depression: An Overview

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    Postpartum depression is a frequent and disabling condition whose pathophysiology is still unclear. In recent years, the study of the neural correlates of mental disorders has been increasingly approached using magnetic resonance techniques. In this review we synthesize the results from studies on postpartum depression in the context of structural, functional, and spectroscopic magnetic resonance studies of major depression as a whole. Compared to the relative wealth of data available for major depression, magnetic resonance studies of postpartum depression are limited in number and design. A systematic literature search yielded only eleven studies conducted on about one hundred mothers with postpartum depression overall. Brain magnetic resonance findings in postpartum depression appear to replicate those obtained in major depression, with minor deviations that are not sufficient to delineate a distinct neurobiological profile for this condition, due to the small samples used and the lack of direct comparisons with subjects with major depression. However, it seems reasonable to expect that studies conducted in larger populations, and using a larger variety of brain magnetic resonance techniques than has been done so far, might allow for the identification of neuroimaging signatures for postpartum depression

    Robotic versus open pancreaticoduodenectomy: Is there any difference for frail patients?

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    Background: Old age and frailty are predictors of early postoperative results after pancreatic surgery. We analysed the results of robotic and open pancreatoduodenectomy in elderly and frail patients.Methods: Data from the local robotic pancreatoduodenectomy database were reviewed and matched with those from open operations during the same period (2014-2020). Both old age and frailty were used to determine any correlation with postoperative outcomes. Elderly patients were defined as patients aged 70 years or more, while frailty was classified according to the validated modified Frailty Index.Results: A total of 118 pancreatoduodenectomies were included in the analysis: 65 (55.1%) robotic and 53 (44.9%) open. More than 50% of patients were frail. Overall, 7.6% of patients experienced grade IV ClavienDindo complications, and 3.4% died within 90 days after surgery. Frail patients experienced a similar rate of severe complications after robotic vs. open operations (5.3 vs. 11.6; p = 0.439) but earlier refeeding (3 days vs. 4 days; p = 0.006) and earlier drain removal (6 days vs. 7 days; p = 0.046) when operated on by a robotic approach. The oncological outcomes, including limphnodes retrieval, residual disease, recurrences, and survival, were not influenced by the surgical approach. Non-elderly patients also showed more benefits with the robotic approach (lower complication index, earlier refeeding, and drain removal).Conclusions: Robotic pancreatoduodenectomy is associated with risks of major complications that are comparable to those of open operation in frail patients. Some perioperative parameters (refeeding, drain removal) seem to favour robotics in frail patients and younger patients, although at the price of longer operating times
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