196,837 research outputs found
Collinge, Susan, September 21, 2018 [Interview]
No full textSusan Collinge was interviewed on September 21, 2019, by Brandon Katzung Hokanson about her childhood, education, early career, and years as an Associate Chaplain at Gettysburg College.Donnella, Joseph; Ramsey, Julie L.; Walters, Kerry; Houwen, HenriGordon A. Haaland Years; Katherine H. Will Years; Janet M. Riggs Years
Janella maculata Collinge 1894
No full textmaculata Collinge, 1894 (Janella) Reference: Cοllinge (1894) Proceedings of the Malacological Society of London, (1894): 526, text-figs. 1, 3, 5. “Fοrty Mile Bush, Nοrth Island, New Zealand ”. Syntypes (2) NHMUK 1896.1.22.33‒4 [NHMUK register indicates “Purchased frοm W.E. Cοllinge”]. Etymοlοgy nοt stated, but clearly in reference tο maculated pigmentatiοn οf the dοrsum. Remarks. Τreated as a juniοr synοnym οf Athoracophorus bitentaculatus (Quοy & Gaimard, 1832) by Suter (1897, 1909a, 1913), Grimpe & Hοffmann (1925), Burtοn (1963) and Pοwell (1979) based οn the descriptiοn by Cοllinge (1894) but withοut cοnsideratiοn οf the type material. Nοt listed by Spencer et al. (2009). Τhe discοvery οf the type material οf Janella maculata in NHMUK (this study) demands reassessment οf its specific status. Nοt Pseudaneitea maculata Burtοn, 1963.Published as part of Barker, Gary M., 2018, Nomenclatural and type catalogue of Athoracophoridae (Mollusca: Eupulmonata: Succineoidea): a synopsis of the first 185 years of biodiscovery in the South West Pacific region, pp. 201-249 in Zootaxa 4434 (2) on page 228, DOI: 10.11646/zootaxa.4434.2.1, http://zenodo.org/record/129052
Collinge et al. reply
No full textREPLYING TO H. H. H. Adams, S. A. Swanson, A. Hofman & M. A. Ikram Nature 537, http://dx.doi.org/10.1038/nature19086 (2016)
The Mouse Social Frailty Index (mSFI): A Standardized Protocol
No full textThe advent of geroscience engendered the development of approaches to quantify the aging process and estimate biological age on an individual level. Recognizing that declines observed in aging are not only physical but also social led us to develop a mouse Social Frailty Index (mSFI) designed to quantify age-related impairments of social functioning in mice. The mSFI consists of seven behavioral assays that measure essential facets of social behavioral functioning in mice: social communication, social interaction, and social functional ability. The assays that comprise the mSFI are all minimally disruptive, relatively simple to execute, and optimized for compatibility with longitudinal studies utilizing experimental interventions relevant to geroscience. The mSFI is conducted over AM and PM sessions spanning a maximum of 3.5 days, using materials common to most animal facilities. The data for all assays is obtained observationally, manually recorded, and entered into predefined template sheets that automate the computation of the mSFI. We have demonstrated the validity and applicability of the mSFI across multiple laboratory sites and experiments. This index has proven to discriminate between differential trajectories of biological aging driven by sex, progeria, or social stress-relevant contexts. The mSFI represents a novel index to quantify trajectories of biological aging in mice, and its application may help elucidate the social dimensions of the aging process
A novel protective prion protein variant that colocalizes with kuru exposure.
No full textBACKGROUND: Kuru is a devastating epidemic prion disease that affected a highly restricted geographic area of the Papua New Guinea highlands; at its peak, it predominantly affected adult women and children of both sexes. Its incidence has steadily declined since the cessation of its route of transmission, endocannibalism. METHODS: We performed genetic and selected clinical and genealogic assessments of more than 3000 persons from Eastern Highland populations, including 709 who participated in cannibalistic mortuary feasts, 152 of whom subsequently died of kuru. RESULTS: Persons who were exposed to kuru and survived the epidemic in Papua New Guinea are predominantly heterozygotes at the known resistance factor at codon 129 of the prion protein gene (PRNP). We now report a novel PRNP variant--G127V--that was found exclusively in people who lived in the region in which kuru was prevalent and that was present in half of the otherwise susceptible women from the region of highest exposure who were homozygous for methionine at PRNP codon 129. Although this allele is common in the area with the highest incidence of kuru, it is not found in patients with kuru and in unexposed population groups worldwide. Genealogic analysis reveals a significantly lower incidence of kuru in pedigrees that harbor the protective allele than in geographically matched control families. CONCLUSIONS: The 127V polymorphism is an acquired prion disease resistance factor selected during the kuru epidemic, rather than a pathogenic mutation that could have triggered the kuru epidemic. Variants at codons 127 and 129 of PRNP demonstrate the population genetic response to an epidemic of prion disease and represent a powerful episode of recent selection in humans
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Dr. Glendon Swarthout
No full textHosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness
- …
