1,626 research outputs found
Improving the researches on Hericium erinaceus for a better use of its medicinal properties in central nervous system
No full textROLE OF 17 B-ESTRADIOL IN LEARNING AND MEMORY
No full textOvarian hormones regulate a wide variety of non-reproductive functions in the central nervous system by interacting
with several molecular and cellular processes. Estrogens are steroid hormones that are synthesized in the gonads
[peripherally-synthesized or “neuroactive steroids”] as well as in various tissues throughout the body, including the
brain [brain-synthetized or “neurosteroids”]. 17β-Estradiol [E2] is the most potent and predominant form of estrogen.
E2 has a number of effects on cognition and brain function. The effects on memory depend on hormone levels and on
binding to different estrogen receptors within neural circuits.
The purpose of this review is to highlight the complex relationship between E2 and cognitive functioning, analyzing
the difference of effects described by observational studies compared to randomized controlled large-scale clinical
trials. We review how E2 signaling affects memory processes: it starts from neurons and reaches superior learning and
memory function through the effect on synapses and on the neuronal network
Figure 1 from: Todisco V, Nazari V, Cesaroni D, Sbordoni V (2017) Preliminary molecular phylogeny and biogeography of the monobasic subfamily Calinaginae (Lepidoptera, Nymphalidae). Zoosystematics and Evolution 93(2): 255-264. https://doi.org/10.3897/zse.93.10744
No full textFigure 1 -
(A) Approximate geographic distributions (Shirôzu 1960, Lang 2012) and sampling localities (circles) for the species of Calinaga included in this study (with the exception of the sample CBUD-INDIN for which we do not have an exact locality). Species as initially identified are highlighted and shown in different colours. Note that many of these initially attributed names subsequently proved erroneous. The map was obtained using Quantum GIS 2.8.2 based on a map from Natural Earth (www.naturalearthdata.com). (B) Median-Joining Network of mtDNA. Circle size proportional to haplotype frequency; number of nucleotide substitutions indicated along connections, except for single or double substitutions. In both figures the species are highlighted and shown in different colours as initially identified
Schermi. Immagini, corpi, condivisioni
No full textIn this book the author investigates the digital image proliferation of our times from an interdisciplinary point of view. Starting from the Visual Culture theoretical frame, Valentina Mignano explores the ways in which we interact with the screen, dealing with the "screen experience" in the first years of the network societ
ENTREPRENEURSHIP AND FEMALE ENTREPRENEURSHIP IN MARAMURES COUNTY
No full textInitiating and developing a business involves a considerable risk and a sustained effort in order to defeat the inertia against what is new. The person initiating a business, assuming the responsibility and risk of its development and benefiting from theentrepreneurship, female entrepreneurship, profit, businesses
The use of initial tocolysis and maintenance tocolysis in preterm birth : guideline-based approach or off-label use - a survey on the current application in Switzerland
No full textAuthor Valentina Schedl, BscMasterarbeit Universität Linz 202
Guido Crepax – Valentina – The Shape of Her Time
No full textThe paper will focus on the analysis of Guido Crepax revolutionary comic book character Valentina that belongs to the golden age of the Italian comic-book genre fumetto. The aim is to explore whether Guido Crepax Valentina character was a "living doll" filling male fantasies of her creator or she was a woman empowered by her author struggling for many of the values of the women's culture that feminists today are trying to introduce into the mainstream. It also addresses research questions that focus on comic books and gender and empowerment at the decade of sexual liberation.Through Valentina case study the present paper is going to study an approach on the concept of woman in comics, and touch the border of female empowerment issue in contemporary world taking in consideration that her revolutionary strong and independent figure was born in a society where women have been frequently viewed as passive and represented as inferior to men and where questions of sexuality were considered taboo. Despite the fact that she angered some feminists by the way she was portrayed as an object of male gaze or a damsel in distress, there is nothing anti-feminist about Valentina. The aim here is to uncover feminist themes in the stories of Valentina and to explore what empowered her and made her a contemporary icon of style and symbol of liberated women
Improving training condition assessment in endurance cyclists: effects of Ganoderma lucidum and Ophiocordyceps sinensis dietary supplementation
No full textThe supplements added to daily diet have the primary objective to maintain good health, improve homeostasis and create conditions for reduction of risk disease. Due to the increasing market demand, the search for effective and non-toxic natural compounds with antioxidant and ergogenic activity has increasingly become a matter of interest.
This paper describes firstly that this specific combination of fungal supplements will be useful in order to assess and manage the performance state of the endurance athlete
Distinct expression patterns of inwardly rectifying potassium currents in developing cerebellar granule cells of the hemispheres and the vermis
No full textG-protein-coupled inwardly rectifying potassium (GIRK) channels play a crucial role during the migration and maturation of cerebellar
granule cells (GCs) in the vermis. In the cerebellar hemispheres, however, only minor effects on the development of GCs
are observed in mice with GIRK channel impairment. This regional difference may reflect distinct ontogenetic expression patterns
of GIRK channels. Therefore, inwardly rectifying responses in mice were characterized at different stages of development in the
vermis and the hemispheres. In the vermis, GCs in the premigratory zone (PMZ) at P7–P15 exhibit GIRK current but not constitutive
inwardly rectifying potassium (CIRK) current, and are relatively depolarized at rest. In contrast, premigratory GCs in the hemispheres
express only CIRK channels, which accounts for their more hyperpolarized resting membrane potential. Furthermore, the
pattern of voltage-dependent inward currents in the PMZ GCs of cerebellar hemispheres is consistent with a more mature stage
of development than the corresponding GCs in the vermis, resulting in robust firing properties mediated by sodium channels.
Later in development (P21–P22), CIRK current is then observed in the majority of vermis GCs. This developmental pattern,
revealed by electrophysiological recordings, was confirmed by immunohistological experiments that showed greater reactivity for
GIRK2 in the PMZ of the vermis than in the hemispheres during development (P7–P15). These findings suggest that regional differences
in development are responsible for the differential expression of inwardly rectifying potassium channels in the vermis
and in the hemispheres
TAXONOMIC COMPOSITION AND MORPHO-FUNCTIONAL TRAITS OF NEMATODES IN MALDIVIAN SUBTIDAL HABITATS
No full textNematodes are one of the most abundant animal phyla in marine bottoms, and show a remarkable diversity
in carbonate sediments. The Maldivian Archipelago is experiencing major environmental changes and
habitat loss, which requires great attention. Previous studies on meiofauna and nematodes from Maldives
have revealed a considerable biodiversity in these sediments that are exclusively carbonate with a highly
porous structure, which offers many microhabitats to meiobenthic organisms. Recently, an important relation
between the morpho-functional traits of nematodes and the loss of ecosystem functioning has been proven.
Thus, the taxonomical structure of the nematode communities of subtidal habitats of Maldives and five
morpho-functional traits (cuticle morphology, tail shape, amphid type, structure of buccal cavity, lifestyle)
were studied. The Maldivian nematode community included 174 genera in 37 families, mainly represented
by Desmodoridae, Chromadoridae and Xyalidae, a faunistic composition in line with that usually found in
this type of sediments. As for morpho-functional traits, the most common cuticle morphology was
dotted/annulated with or without lateral differentiation (80% of the community).The most common type of
amphid was loop-like in 42% of the community, followed by spiral (21%), circular (16%) and slit (11%).
The analysis of trophic groups showed the prevalence of epistrate feeders (2A, 54%), followed by selective
deposit feeders (1A, 22%), omnivorous (2B, 14%) and non-selective depositories (1B, 11%). As for life
strategy, the colonizer-persisters class 3 (c-p 3) made up the 57% of the community, the c-p 2 22%, and c-p 4
20%. Statistical analysis allowed to detect interesting relations between nematode morpho-functional traits,
especially amphid type and cuticle morphology, and some environmental features. For instance, a significant
presence of nematodes with the peculiar cuticle provided with desmi was found in the outer reefs, likely
related to the high abundance of Desmoscolecidae, a family typical of very heterogeneous sediments and
highly hydrodynamic habitats just like the outer reefs. Instead, nematodes with a bacteria-coated cuticle were
more numerous in the inner reefs: this cuticle occurs in the subfamily Stilbonematinae (fam. Desmodoridae),
that is often associated to sediments with low hydrodynamism and hypoxic conditions as are those found in
inner reefs. The bladder-like amphid typical of Desmoscolecidae appeared relevant to discriminate the
habitat of the outer reef, whereas the pocket-like amphid was definitely more represented in nematodes of the
inner reefs. No literature data about the relation amphid -habitat are available, but a correlation of the amphid
type with the hydrodynamic regime is likely
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