3,207 research outputs found
La morte di Catone e l'opposizione intellettuale a Cesare e ad Augusto
No full textIl Cato di Cicerone; l'Anticato di Cesare; la biografia catoniana di Munazio Rufo; i Rescripta Bruto de Catone di Augusto: la prima fortuna del 'mito' di Caton
Expression of Endothelin-1 and Endothelin Receptor A in Canine Ovarian Tumours
No full textOvarian tumours have a low incidence in bitch. Endothelin (ET-1) and endothelin A receptor (ET-A) are overexpressed in human ovarian cancer. Twenty canine ovarian tumours and five normal samples were first evaluated by western blotting and then immunohistochemically for ET-1 and ET-A expression. Seventeen out of twenty tumours were ET-1 positive. Eight out of twenty tumours were ET-A immunohistochemically positive. At molecular level both proteins were proven to be expressed in normal as well as in tumour samples. Our results show that ET-1 and ET-A are overexpressed in canine ovarian tumours, suggesting a potential role of these two molecules in canine ovarian carcinogenesis
The Fake News Phenomenon in the Scientific Debate: Evidence from a Bibliometric Analysis
No full textNavigating the vast sea of information in the digital age poses significant challenges, espe cially when it comes to discerning fake news from authentic information. This intricate task becomes even more challenging when the fake news is artfully presented as truth. Fake news often disguises itself as credible content and, by rapidly proliferating on digital platforms, contributes to increasing information disorder. This paper aims to investigate how the fake news phenomenon and its related issues have been addressed in the scientific literature. To achieve this objective, we conducted a bibliometric analysis of 3098 scientific publications extracted from the Web of Science from 2005 to 2022. This approach allowed us to identify the conceptual structure of fake news, including the different themes, and understand how they are interconnected in the field of fake news study. Additionally, we examined the intellectual structure based on the co-citations of key journals addressing this topic. The results of this research revealed an increase in the volume of fake news publications, coinciding with a rise in citations among the authors of the selected articles. Furthermore, we found that the conceptual structure of fake news is characterised by an interdisciplinary nature, which revolves mainly around sociopolitical dynamics and public health, with the latter particularly influenced by the global impact of the COVID-19 pandemic. Finally, the intellectual structure uncovered by the journals’ co-citation network highlights the presence of two main subfields: communication and political debate and the behavioural domai
Uterine malignant mixed Mullerian tumor (metaplastic carcinoma) in the cat: Clinicopathologic features and proliferation indices.
No full text
Immunohistochemical and lectin histochemical analysis of the alpaca efferent ducts.
No full textAn immunohistochemical and lectin
histochemical study of the efferent ducts was performed
in the alpaca. Two types of epithelium, consisting of
principal and ciliated cells, were detected on the basis of
the different cytokeratins expression and lectin binding
pattern. AE1/AE3 and 13 cytokeratin antibodies
intensely immunostained the entire cytoplasm of type I
PCs, whereas AE1/AE3, but not anti cytokeratin 13,
immunoreacted in type II principal cells along the apical,
lateral and basal plasma-membrane.
The histochemical characterization of the epithelial
cells was carried out using a battery of different lectins:
Con-A, UEA-I, LTA, WGA, GSA-II, GSA-IB4, SBA,
PNA, ECA, DBA, MAL-II and SNA. Sialidase digestion
and deglycosilation pre-treatments were also employed.
In type I principal cells, the staining of the Golgi
zone was interpreted giving evidence for the synthesis
and secretion of O- and N-linked oligosaccharides. In
particular, a-Man/a-Glc, GlcNAc, ß-Gal-(1-4)-GlcNAc,
Neu5Aca2,3Gal and Neu5Aca2,6Gal/GalNAc residues
were included in both O- and N-linked glycans, whereas
a-Fuc, ß-GalNAc and a-Gal were only found in Olinked
oligosaccharides; a-GalNac and ß-Gal-(1-3)-DGalNAc
were found subterminal to sialic acid moieties
and they were included in O- and N-glycans. In type II
principal cells, the lectin staining was observed in the
apical cytoplasmic granules and in vacuoles that were
interpreted as components of an elaborate endocytotic
apparatus specialized for the uptake of particulate
material and fluid from the lumen. These results suggest
the existence of two structurally different epithelial
segments along the ductuli efferentes of the alpaca, with
a high degree of compartmentalization of the secretory
and absorptive activities
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