1,720,972 research outputs found

    Ductal Adenocarcinoma: Downstaging

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    Pancreatic ductal adenocarcinoma (PDAC) is usually diagnosed at an advanced stage of disease with involvement of major peripancreatic vessels, extra-pancreatic invasion, or metastases. For this reason, fewer than 20% of patients are suitable for surgical resection (Laeseke et al., Radiology 277:644–661, 2015). An increasing number of unresectable PDACs undergo surgery after neoadjuvant therapy. Unresectable PDAC patients, including locally advanced and borderline resectable cancers, can be downstaged by neoadjuvant chemoradiotherapy. Resectability of PDAC is a multidisciplinary concept, and imaging has a central role for the proper description of the extent of tumor. High-quality imaging of the pancreas should be performed at presentation and following neoadjuvant treatments to provide adequate staging and assessment of resectability status. Restaging after chemotherapy is always more problematic with a lower accuracy by using imaging modalities to correctly assess therapeutic responses and downstaging

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Mucinous Neoplasms

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    Mucinous cystic neoplasms (MCNs) are thick-walled, uni- or multilocular tumors composed of mucin-containing cysts. These neoplasms occur almost exclusively in women and are mainly located in the body-tail of the pancreas. MCNs encompass a spectrum of lesions from benign lesions (i.e., mucinous cystadenoma, MCA) to invasive mucinous cystadenocarcinoma

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Mimickers of Pancreatic Tumor

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    Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic malignant neoplasm. Misdiagnosis could be a problem dealing with differential diagnosis of pancreatic masses. Also benign pancreatic conditions may mimic pancreatic tumors. This chapter is focused on a brief presentation of possible non-neoplastic mimickers of pancreatic tumors and differential diagnosis

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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