1,767,221 research outputs found
CAPA 2023 Conference Invitation: CAPA 2023
No full textRegistration for CAPA 2023 Now Open!
The CAPA Annual Conference is the only national conference designed for Canadian physician assistants by physician assistants. The conference attracts Canadian and international PAs looking for high-calibre continuing professional development opportunities, learning from national and international experts, and networking and sharing expertise. With over 19 hours of high-calibre CPD, highlights will include:
Workshops throughout
Exhibit hall with networking breaks
Welcome Reception Thursday, October 19 from 6:30pm to 8:30pm
Awards Ceremony and President’s Dinner on Saturday, October 21 at 7:30 pm
We hope to see you there!
Call for E-Posters Submit your abstract by September 11
Have you conducted a research project? Do you have valuable data to share? Submitting a poster abstract is an important way to showcase your knowledge and expertise amongst your peers. Please consult the selection criteria before making your submission. Poster abstracts will be accepted in the following categories:
original research
case report
educational resources and interventions
All poster abstracts are automatically entered into the competition for Poster Awards, which are presented at the annual Awards Ceremony and President’s Dinner on Saturday, October 21, 2023. All posters will be displayed electronically for the duration of the conference.
For Further Information: 877 744 2272 │[email protected] │capa-acam.c
ACAM - Apposed Cortex Adhesion Model
No full textACAM: an Apposed-Cortex Adhesion Model of an epithelial tissue.
The ACAM library is an implementation of a mechanical model of an active epithelial tissue. See bioRxiv 10.1101/2021.04.11.439313 for the modelling and results.
How is the cell cortex represented?
Each cell cortex in ACAM is represented as an active, continuum morphoelastic rod with resistance to bending and extension. By explicitly considering both cortices along bicellular junctions, the model is able to replicate important cell behaviours that are not captured in many existing models e.g. cell-cell shearing and material flow around cell vertices.
How are adhesions represented?
Adhesions are modelled as simple springs, explicitly coupling neighbouring cell cortices. Adhesion molecules are given a characteristic timescale, representing the average time between binding and unbinding, which modules tissue dynamics
Mechanism and function of drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor
No full textThe capa peptide receptor, capaR (CG14575), is a G-protein coupled receptor (GPCR) for the D. melanogaster capa neuropeptides, Drm-capa-1 and -2 (capa-1 and -2). To date, the capa peptide family constitutes the only known nitridergic peptides in insects, so the mechanisms and physiological function of ligand-receptor signalling of this peptide family are of interest. Capa peptide induces calcium signaling via capaR with EC50 values for capa-1 = 3.06 nM and capa-2 = 4.32 nM. capaR undergoes rapid desensitization, with internalization via a b-arrestin-2 mediated mechanism but is rapidly re-sensitized in the absence of capa-1. Drosophila capa peptides have a C-terminal -FPRXamide motif and insect-PRXamide peptides are evolutionarily related to vertebrate peptide neuromedinU (NMU). Potential agonist effects of human NMU-25 and the insect -PRLamides [Drosophila pyrokinins Drm-PK-1 (capa-3), Drm-PK-2 and hugin-gamma [hugg]] against capaR were investigated. NMU-25, but not hugg nor Drm-PK-2, increases intracellular calcium ([Ca2+]i) levels via capaR. In vivo, NMU-25 increases [Ca2+]i and fluid transport by the Drosophila Malpighian (renal) tubule. Ectopic expression of human NMU receptor 2 in tubules of transgenic flies results in increased [Ca2+]i and fluid transport. Finally, anti-porcine NMU-8 staining of larval CNS shows that the most highly immunoreactive cells are capa-producing neurons. These structural and functional data suggest that vertebrate NMU is a putative functional homolog of Drm-capa-1 and -2. capaR is almost exclusively expressed in tubule principal cells; cell-specific targeted capaR RNAi significantly reduces capa-1 stimulated [Ca2+]i and fluid transport. Adult capaR RNAi transgenic flies also display resistance to desiccation. Thus, capaR acts in the key fluid-transporting tissue to regulate responses to desiccation stress in the fly
Entrevista con Robert Capa
No full textEn 1947 el mítico fotorreportero Robert Capa publicaba “Slightly out of focus” (Ligeramente desenfocado, La Fábrica, 2015), una suerte de autobiografía o crónica de sus aventuras durante la Segunda Guerra Mundial. Como parte de la campaña de promoción, Capa acudió al programa radiofónico “Hi! Jinx”, para charlar con sus presentadores, el matrimonio formado por Jinx Falkenbrug y Tex McCrary. El programa había desaparecido en manos de un vendedor de Massachussets que había descubierto aquella grabación junto con otras de la época den una venta de enseres domésticos en su ciudad. Minerva transcribe esa entrevista cuyo registro sonoro formó parte de la exposición del CBA Capa en color. En ella Capa habla, entre otras cosas, de su viaje a la URSS junto a John Steinbeck, de la invención de su nombre y de su famosa imagen “Muerte de un miliciano”
Insect capa neuropeptides impact desiccation and cold tolerance
No full textThis work was funded by grants from the UK Biotechnology and Biological Sciences Research Council (BB/G020620 and BB/L002647/1) (to S.-A.D., J.A.T.D., and S.T.); US Department of Agriculture/Department of Defense Deployed War Fighters Protection Grant Initiative (#6202-22000-029-00D) and US–Israel Binational Agricultural Research and Development Fund (BARD) (IS-4205-09C) (R.J.N.); and the National Science Foundation (IOS-0840772) (D.L.D.).The success of insects is linked to their impressive tolerance to environmental stress, but little is known about how such responses are mediated by the neuroendocrine system. Here we show that the capability (capa) neuropeptide gene is a desiccation- and cold stress-responsive gene in diverse dipteran species. Using targeted in vivo gene silencing, physiological manipulations, stress-tolerance assays, and rationally designed neuropeptide analogs, we demonstrate that the Drosophila melanogaster capa neuropeptide gene and its encoded peptides alter desiccation and cold tolerance. Knockdown of the capa gene increases desiccation tolerance but lengthens chill coma recovery time, and injection of capa peptide analogs can reverse both phenotypes. Immunohistochemical staining suggests that capa accumulates in the capa-expressing Va neurons during desiccation and nonlethal cold stress but is not released until recovery from each stress. Our results also suggest that regulation of cellular ion and water homeostasis mediated by capa peptide signaling in the insect Malpighian (renal) tubules is a key physiological mechanism during recovery from desiccation and cold stress. This work augments our understanding of how stress tolerance is mediated by neuroendocrine signaling and illustrates the use of rationally designed peptide analogs as agents for disrupting protective stress tolerance.Peer reviewe
Capa y Taro: acercarse lo suficiente
No full textLa exposición Gerda Taro / This is war! Robert Capa at work reunió fotografías realizadas por Robert Capa en los conflictos que cubrió como reportero de guerra, junto con imágenes tomadas durante la Guerra Civil española por Gerda Taro, su compañera sentimental. Capa y Taro �cuyos verdaderos nombres eran Endre Friedmann y Gerta Pohorylle� se encontraron en París, donde urdieron un subterfugio que les iba a permitir comercializar mejor sus fotos. De esta manera surgió el nombre de Robert Capa, un supuesto fotógrafo norteamericano del que Endre y Gerta se decían sus representantes. Así, en un primer momento, las fotografías que vendían bajo este seudónimo eran indistintamente de uno u otro, aunque más adelante Friedmann se quedó con el nombre por el que sería internacionalmente conocido como uno de los fotógrafos más importantes del siglo XX.
La Guerra Civil española marca de forma definitiva sus vidas. Ambos acuden en 1936 a cubrir el conflicto, publicando sus imágenes en revistas como Vu o Regreds. La dedicación a su trabajo se salda con la temprana desaparición de Taro, arrollada por un tanque en el frente de Brunete. Capa permaneció en España hasta la retirada final en Cataluña, y más tarde entregó al mundo imágenes de los principales escenarios bélicos de Europa durante la II Guerra Mundial. Años más tarde, Capa pierde la vida en la Guerra de Indochina, víctima quizá de su propia máxima: «Si tus fotos no son buenas es que no te has acercado lo suficiente».
Minerva brinda ahora desde sus páginas un homenaje a ambos fotógrafos y a la labor de los reporteros de guerra. Para ello, hemos invitado a comentar algunas de las instantáneas de Capa y Taro a seis corresponsales de guerra: Gervasio Sánchez, Alfonso Armada, Guillaume Fourmont, Miguel-Anxo Murado, Carlos Enrique Bayo y Guillermo Altares
CAPA Conference 2016: Incubating Long Form in Film Schools
No full textResearch Background
The CAPA Conference 2016 brought together educators and practitioners from around the globe to debate the role of and best practices in making long form screen productions as part of a film school education.
Research Contribution
The CAPA 2016 Conference topic ‘Incubating Long-Form at Film Schools’ seemed to be a controversial one. During the preparation for the conference, we talked to many people about their opinion on feature films as part of filmmaking education. We were either met with astonishing enthusiasm or heartfelt disapproval - rarely anything in between. The time for a debate seemed ripe. We wanted the CAPA Conference to be as much a celebration of long formats as part of film education as a critical investigation of it. For this reason, we organised the conference as a research project that explored how to best bridge the gap between short film exercises and long-form filmmaking in the career paths of today’s filmmakers.
At the heart of the 2-day conference were panel discussion between 27 panelists. Panels had been carefully curated. Every presenter was an invited speaker and who shared a case study of what could be considered a ‘best practice’ example. Presentations were meant to create a rich overview of the different models of making long-form content within film education.
Research Significance
CAPA is the Asia-Pacific regional association of CILECT - the international association of film and television schools. The CAPA 2016 Conference brought together over 120 attendees from the Asia-Pacific, Europe, the Americas and Africa.Full Tex
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