1,363 research outputs found
Managing Risk in International Inbound Supply Chains in: Developments in Logistics and Supply Chains: past, present and future
No full textOptimal 1D Ly α forest power spectrum estimation - III. DESI early data
No full textKaraçaylı, Naim Göksel et al.-- Full list of authors: Karaçaylı, Naim Göksel; Martini, Paul; Guy, Julien; Ravoux, Corentin; Abdul Karim, Marie Lynn; Armengaud, Eric; Walther, Michael; Aguilar, J.; Ahlen, S.; Bailey, S.; Bautista, J.; Beltran, S. F.; Brooks, D.; Cabayol-Garcia, L.; Chabanier, S.; Chaussidon, E.; Chaves-Montero, J.; Dawson, K.; de la Cruz, R.; de la Macorra, A.; Doel, P.; Font-Ribera, A.; Forero-Romero, J. E.; Gontcho, S. Gontcho A.; Gonzalez-Morales, A. X.; Gordon, C.; Herrera-Alcantar, H. K.; Honscheid, K.; Iršič, V.; Ishak, M.; Kehoe, R.; Kisner, T.; Kremin, A.; Landriau, M.; Le Guillou, L.; Levi, M. E.; Lukić, Z.; Meisner, A.; Miquel, R.; Moustakas, J.; Mueller, E.; Muñoz-Gutiérrez, A.; Napolitano, L.; Nie, J.; Niz, G.; Palanque-Delabrouille, N.; Percival, W. J.; Pieri, M.; Poppett, C.; Prada, F.; Pérez-Ràfols, I.; Ramírez-Pérez, C.; Rossi, G.; Sanchez, E.; Seo, H.; Sinigaglia, F.; Tan, T.; Tarlé, G.; Wang, B.; Weaver, B. A.; Yéche, C.; Zhou, Z..-- This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.The 1D power spectrum P1D of the Ly α forest provides important information about cosmological and astrophysical parameters, including constraints on warm dark matter models, the sum of the masses of the three neutrino species, and the thermal state of the intergalactic medium. We present the first measurement of P1D with the quadratic maximum likelihood estimator (QMLE) from the Dark Energy Spectroscopic Instrument (DESI) survey early data sample. This early sample of 54 600 quasars is already comparable in size to the largest previous studies, and we conduct a thorough investigation of numerous instrumental and analysis systematic errors to evaluate their impact on DESI data with QMLE. We demonstrate the excellent performance of the spectroscopic pipeline noise estimation and the impressive accuracy of the spectrograph resolution matrix with 2D image simulations of raw DESI images that we processed with the DESI spectroscopic pipeline. We also study metal line contamination and noise calibration systematics with quasar spectra on the red side of the Ly α emission line. In a companion paper, we present a similar analysis based on the Fast Fourier Transform estimate of the power spectrum. We conclude with a comparison of these two approaches and discuss the key sources of systematic error that we need to address with the upcoming DESI Year 1 analysis.This material is based upon work supported by the U.S. Department
of Energy (DOE), Office of Science, Office of High-Energy Physics,
under Contract No. DE–AC02–05CH11231, and by the National
Energy Research Scientific Computing Center, a DOE Office of
Science User Facility under the same contract. Additional support
for DESI was provided by the U.S. National Science Foundation
(NSF), Division of Astronomical Sciences under Contract No.
AST-0950945 to the NSF’s National Optical-Infrared Astronomy
Research Laboratory; the Science and Technology Facilities Council
of the United Kingdom; the Gordon and Betty Moore Foundation;
the Heising–Simons Foundation; the French Alternative Energies
and Atomic Energy Commission (CEA); the National Council of
Science and Technology of Mexico (CONACYT); the Ministry of
Science and Innovation of Spain (MICINN), and by the DESI Member Institutions: https://www.desi.lbl.gov/collaborating-institutions.
Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not
necessarily reflect the views of the U.S. National Science Foundation, the U.S. Department of Energy, or any of the listed funding
agencies.
The authors are honoured to be permitted to conduct scientific
research on Iolkam Du’ag (Kitt Peak), a mountain with particular
significance to the Tohono O’odham NationPeer reviewe
Comparison of first- and second-generation drug-eluting stents in saphenous vein grafts used as aorto-coronary conduits
No full textComparison of results of transcatheter aortic valve implantation in patients with severely stenotic bicuspid versus tricuspid or nonbicuspid valves
No full textData on transcatheter aortic valve implantation (TAVI) for severe bicuspid aortic valve (BAY) stenosis and how this compares to that for tricuspid aortic valve (TAV) stenosis are limited. Twenty-one consecutive patients with BAV were treated with the Edwards or Core Valve bioprosthesis from November 2007 to December 2012 at San Raffaele Scientific Institute and Clinical Institute S. Ambrogio, Milan, Italy. Results were compared with a cohort of patients with TAV (n=447) treated with the same bioprostheses over the same period. Procedural 1- and 12-month outcomes were examined as defined by the Valve Academic Research Consortium criteria. Patients with BAY were younger (76.7 +/- 7.1 vs 79.8 +/- 7.4 years, p=0.06) and with a larger aortic annulus (25.0 +/- 1.8 vs 23.6 +/- 2.1 mm, p=0.01). Device success (85.7% vs 94.4%, p=0.10) was lower in patients with BAY. Although the 30-day composite safety end point (23.8% vs 21.0%, p=0.76) was similar between the 2 groups, mortality rate at 30 days was higher (14.2% vs 3.6%, p=0.02) in the BAY group. Cardiovascular mortality at 1 year did not differ significantly between the 2 groups (10.5% vs 7.4%, p=0.62). In conclusion, transcatheter aortic valve implantation in high surgical risk patients with severe BAY stenosis appears to be feasible with mid-term cardiovascular mortality similar to that for patients with TAV. Early survival and device success, however, were lower for patients with BAY demonstrating that further studies are required to identify which subset of patients with BAY is best suited for transcatheter treatment. (C) 2014 Elsevier Inc. All rights reserved. OI Naim, Charbel/0000-0002-4346-399
The role of everolimus-eluting and resolute zotarolimus-eluting stents in the treatment of coronary bifurcations
No full textA control engineering approach to the assessment of supply chain resilience
No full textThis is an Author's Accepted Manuscript of an article published in International Journal of Production Research, 50(21), 6162 - 6187, 2012 [copyright Taylor & Francis], available online at: http://www.tandfonline.com/10.1080/00207543.2012.710764.There is no consensus on the supply chain management definition of resilience. To aid in evaluating the dynamic behaviour of such systems we need to establish clearly elucidated performance criteria that encapsulate the attributes of resilience. A literature review establishes the latter as readiness, responsiveness and recovery. We also identify robustness as a necessary condition that would complement resilience. We find that the Integral of the Time Absolute Error (ITAE) is an appropriate control engineering measure of resilience when it is applied to inventory levels and shipment rates. We use the ITAE to evaluate an often used benchmark model of make-to-stock supply chains consisting of three decision parameters. We use both linear and nonlinear forms of the model in our evaluation. Our findings suggest that optimum solutions for resilience do not yield a system that is robust to uncertainties in lead-time. Hence supply chains will experience drastic changes in their resilience performance when lead-time changes
Targeting prostate cancer cells with D2B-gold Nanoparticles
No full textIn this study, gold nanoparticles (AuNPs) with an estimate diameter of 25 nm have been synthesized in water using sodium citrate as both reducing and stabilizing agent at ~95 C and in the presence of sodium hydroxide. The generated AuNPs were characterized using ultraviolet-visible spectroscopy (UV-Vis), dynamic light scattering (DLS) and Zeta potential measurements. Additionally, AuNPs were coated with D2B, a monoclonal antibody (mAb) recognizing an extracellular epitope of the human prostate specific membrane antigen (hPSMA). Binding of antibodies to PSMA induces its endocytosis, thereby marking PSMA as a docking site for the delivery of therapeutic agents. To attain a stabilized and covalent bond between D2B and AuNPs the strong S-Au bond was exploited; so, the sulfhydryl group (SH) in a cysteine of the D2B was utilized. Binding of D2B to AuNPs-citrate colloidal solution caused a red shift with a higher wavelength of about 15 nm in the UV-Vis spectra. Furthermore, as a confirmation of the successful conjugation, DLS revealed an increase in both the AuNPs size from ~25 to ~63 nm and Zeta potential measurements for AuNPs-citrate from ~ -45 mV to -23 mV. The cytotoxicity of D2B-AuNPs was assessed using the WST-1 cell proliferation assay and the agarose gel DNA fragmentation method. Finally, the specific delivery and binding of our customized NPs was tested using flow cytometry and western blot. Our results pave the way for further research using coated NPs as vehicles for drug delivery in in vitro as well as in vivo models
STUDI METODE KORELASI PENGETAHUAN MASYARAKAT TENTANG MANFAAT VITAMIN C DAN KONSUMSI SUPLEMEN VITAMIN C DI DESA JIPO KECAMATAN KEPOHBARU KABUPATEN BOJONEGORO
No full textVitamin C adalah jenis vitamin yang mudah larut dalam air dan mempunyai fungsi penting dalam menangkal sumber penyakit atau sebagai antioksidan. Sedangkan suplemen adalah zat aditif yang isi kandunganya berupa nutrisi baik bagi tubuh. Vitamin C umumnya bersifat organik dan bersumber dari buah buahan, atau sayur-sayuran, sedangkan dalam bentuk suplemen adalah zat yang di buat secara mekanik (olahan pabrik) biasanya berupa obat seperti pil, tablet, kapsul ataupun cairan dan sebagainnya. Tujuan dari penelitian ini untuk mengidentifikasi pengetahuan masyarakat tentang manfaat vitamin C dan hubungan pengetahuan masyarakat tentang manfaat vitamin C dengan tingkat konsumsi suplemen vitamin C. Penelitian ini merupakan penelitian kuantitatif dengan kombinasi desain analisis korelasi mengunakaan dua jenis penelitian yang di gabungkan jadi satu, yaitu jenis penelitian kualitatif dan kuantitatif yang dilakukan di desa Jipo Rt 07 Rw 02 Kecamatan Kepohbaru Kabupaten Bojonegoro Jawa Timur dengan responden sebanyak 50 sampel, 30 responden berjenis kelamin laki-laki dan 20 responden berjenis kelamin perempuan, dengan metode wawancara dan quesioner. Tingkat pengetahuan masyarakat mempengaruhi tingkat konsumsi suplemen vitamin C, sedangkan baik buruknya keadaan tubuh sangat di pengaruhi oleh vitamin C. Oleh karena itu analisis data yang di peroleh menunjukan angka sebanyak 4% untuk responden dengan tingkat pengetahuan yang kurang, sedangkan 14% responden dengan tingkat pengetahuan yang cukup, dan 82% responden dengan tingkat pengetahuan baik. Tingkat konsumsi suplemen vitamin C sudah termasuk baik, hubungan keduanya adalah tingkat pengetahuan masyarakat mempengaruhi tingkat konsumsi suplemen vitamin C, sedangkan baik buruknya keadaan tubuh sangat di pengaruhi oleh vitamin C dibuktikan pada hasil analisis, bahwa 74% responden mengonsumsi suplemen vitamin C dengan pengetahuan tinggi dan hanya 26% responden yang tidak mengonsumsi suplemen vitamin C dengan pengetahuan rendah
Toward Sustainable, Colorless, and Transparent Photovoltaics: State of the Art and Perspectives for the Development of Selective Near-Infrared Dye-Sensitized Solar Cells
No full textDye-sensitized solar cell (DSSC) is one of the promising photovoltaic (PV) technologies for applications requiring high aesthetic features combined with energy production such as building integration PV (BIPV). In this context, DSSCs have the ability to be wavelength selective, thanks to the development of new sensitizers by molecular engineering. The long history of dye research has afforded is technology different colorations for reaching panchromatic light absorption. However, nearly 45% of radiation from sunlight lies in the near-infrared (NIR) region, where human cones are not sensitive. This review provides the reader with key information on how to selectively exploit this region to develop colorless and transparent PV based on DSSC technology. Besides selective NIR absorbers, the triptych photoanode, counter-electrode, and redox mediator are together contributing to reach high aesthetic features. Details of all the components, interplay, and an opinion on the technological limitations to reach colorless and transparent NIR-DSSC are herein discussed in relationship with BIPV applications
Rika Zaraï chante Israël / Rika Zaraï et l'orchestre, dir. : Yohanan Zaraï
No full textComprend : HAVA NETZEI BAHAMOL : folklore / Arrgt. : Y. Zaraï - BREV CHEL CHOCHANIM / M. Dor, Y. Hadar - VAY HAZKEM : texte biblique / Y. Zaraï - DODI LI : texte biblique / Nira-Chen - SHIR HANOKDIM / M. Dor, Y. Hadar - HALLELOU / N. Naim, L. Romann, Y. Zaraï - TAPOUAH HENANI / Y. Napar - HENE MA TOV / M. Jacobson, C. C. Carter - YOM HADASCH / A. Ettinger, Y. Zaraï - HAVA NAGUILA : folklore / Arrgt. : S. DanoffBnF-Partenariats, Collection sonore - BelieveContient une table des matière
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