201 research outputs found
Demócrito “Bernardo” Bitti, SJ. Un pintor de las Marcas hacia el Nuevo Mundo
No full textDemocrito “Bernardo” Bitti, who joined the Society of Jesus in 1568, is considered one of the great Italian masters who were a stylistic influence on the first generation of Peruvian artists. His life and work in Italy and Peru have been studied by the author as part of her master thesis, recently defended at the University of Turin. The article presents for the first time the results of this investigation, as well as new documental discoveries on Bitti retrieved in Italian archives (ARSI and Camerino), focusing mainly on his youth and family. These materials allow to reconstruct his life before the arrival to Peru, and to propose new hypothesis on his artistic training in the Marche region. The analysis of Bitti’s South American catalogue, including the most recent discoveries, shows his relevance as a missionary in Peru, where his art served to illustrate the jesuit evangelical effort.Ingresado en la Compañía de Jesús en 1568, el pintor Demócrito “Bernardo” Bitti es considerado como uno de los grandes maestros italianos que con su estilo influenciaron a las primeras generaciones de pintores virreinales peruanos. Su vida y actividad artística en Italia y Perú han sido el objeto de una tesis magistral conducida por la autora y sustentada en julio 2018 en la Universidad de Turín (Italia). En este artículo se presentan por primera vez los resultados de ese trabajo, introduciendo nuevas evidencias documentales sobre Bitti que se encontraron en los archivos italianos (en el ARSI de Roma y en Camerino), materiales inéditos sobre su juventud y su familia que permiten reconstruir su vida antes de llegar a Perú y avanzar hipótesis concretas sobre su formación artística en las Marcas.
El análisis de su catálogo sudamericano, actualizado a los últimos hallazgos, muestra sin duda la importancia de Bitti como misionero en Perú, donde con su arte fue intérprete del mensaje de evangelización jesuita. Palabras clave: Bitti, Manierismo, pintura virreynal, ARS
Yine Bitti Gün
No full textYine Bitti Gün (The Day Ended Again) presents a personal selection of poems written by Yüksel Özdemir from the 1990s to the present day. The author, raised on the philosophy of her Village Institute-educated parents, centers her Atatürkist and Republican identity in her life and work. The poems strongly express reverence and a sense of indebtedness to the heroes of national struggles, such as the Çanakkale War and the War of Independence. The work also conveys her dedication as a teacher to her profession and the enlightened legacy of the Village Institutes , while lyrically exploring personal themes like family, parental love, longing, despair, and solitude. These poems demonstrate her sensitivity to social issues (children's rights, violence) and political events (the ban on the "Andımız" student oath, the remembrance of Uğur Mumcu), serving as a journey into both the author's personal and societal pastYine Bitti Gün, Yüksel Özdemir'in 1990'lı yıllardan günümüze dek yazdığı şiirlerden oluşan kişisel bir seçkiyi sunmaktadır. Yazar, Köy Enstitülü anne ve babasının felsefesiyle büyümüş, Atatürkçü ve Cumhuriyetçi kimliğini yaşamının ve eserlerinin merkezine koymuştur. Kitaptaki şiirler; Çanakkale Savaşı ve Kurtuluş Savaşı gibi ulusal mücadele dönemlerine duyulan saygıyı ve o günlerin kahramanlarına borçluluk hissini güçlü bir dille ifade eder. Eser aynı zamanda, bir öğretmen olarak mesleğine ve Köy Enstitüleri'nin aydınlanmacı mirasına bağlılığını dile getirirken , kişisel temaları (aile, evlat sevgisi, özlem, umutsuzluk ve yalnızlık) da lirik bir üslupla işler. Toplumsal sorunlara (çocuk hakları, şiddet) ve siyasi olaylara (Andımız yasağı, Uğur Mumcu'nun anılması) duyarlılığını sergileyen bu şiirler, yazarın hem kişisel hem de toplumsal geçmişine dönük bir yolculuğudur
Two distinctive HLA haplotypes harbor the B27 alleles negatively or positively associated with ankylosing spondylitis in Sardinia: implications for disease pathogenesis.
No full textPsychological factors associated with medication adherence following renal transplantation
No full textBACKGROUND: A relationship exists between non-adherence and clinical outcomes in health care, including renal transplantation. The aim of this study was to identify the psychological variables associated with non-adherence to medication after renal transplantation. METHODS: This cross-sectional study involved 34 patients, 38% male, with a mean age of 49 yr (range 26-70) and a mean of six yr post-transplantation. Adherence to medication was measured by two items: (i) the frequency of not taking medications and (ii) the frequency of not taking medications exactly as prescribed. The psychological variables were: dispositional coping style (COPE) and five items measuring barriers and perceived characteristics of the medication regimen. Descriptive and multivariate analyses were utilized to examine the data. RESULTS: Twenty-four per cent of patients reported less than perfect adherence. Individuals who were younger, who perceived less autonomy in the management of treatment and who were characterized by an active coping style were less likely to adhere to medication. Individuals who perceived less autonomy and a higher level of interference of treatment with their life patterns were less likely to take medication exactly as prescribed. CONCLUSIONS: The finding of this study suggests that adherence to medications after renal transplant is associated with psychological variables, such as coping style and perceived autonomy in the management of treatment. Understanding of the patient's perspective may help to develop effective interventions to increase the levels of adherence to medications that may result in better clinical outcomes
Nonverbal communication and cultural differences: issues for face-to-face communication over the internet
No full textThe various forms of interpersonal communication that take place on the internet are considered and several questions concerning the efficacy of interpersonal communication over the internet are raised (i.e. whether this form of communication can be compared to actual face to face communication, ...).
The means of communication over the internet not ever allow access to “kinesic” behaviours through the visual channel or to vocal-intonational modulations of speech through the auditory channel; they cannot therefore count on a wide range of non-verbal signals that are of extreme importance for certain communicative processes.
Graphic and linguistic strategies permit internet users to compensate for this lack of communicative signals and make communication via internet more immediate, natural, spontaneous and expressive. The videoconference too would be an effective means for guaranteeing the sense of presence to interlocutors; it can be used in many different areas: at work (long-distance collaboration and meetings between people in different locations), long-distance education (teleteaching, e-learning); health (telemedicine, telehealth, psychotherapy), in legal contexts.
This contribution, finally, analyses the videocommunication interactions between individuals belonging to different cultures and evaluates the differences in non verbal communication in this perspective
Effects of mode, consonance, and register in a picture-, and word-evaluation affective priming task
No full textBackground
Sollberger, Reber, and Eckstein (2003), using an affective priming paradigm, have demonstrated
that the affective tone of musical chords influences the evaluation of target words. Affective tone was manipulated using consonant and dissonant chords, and target words were pleasant or unpleasant.
The results showed that negative targets were evaluated significantly faster if preceded
by a dissonant rather than a consonant chord.
Aims
The paradigm of affective priming was applied to verify if: (a) major and minor chords presented
in high and low register can significantly influence reaction times and response accuracy in a wordevaluation
task with happy and sad words as targets; (b) major and minor chords presented in high
and low register can significantly influence reaction times and accuracy in a picture-evaluation
task with happy and sad pictures as targets; (c) consonant and dissonant chords presented in high
and low register can significantly influence reaction times and accuracy in a picture-evaluation
task with pleasant and unpleasant pictures as targets.
Method
The three hypotheses were tested in three different studies. The first one involved 70 participants,
the second one 27, and the third one 29. Participants were university students without professional
music training. Major and minor chords were major and minor C triads. Dissonant chords were
composed by D-G#-D’. Register was manipulated presenting chords at two octave distance. Prime
chords were presented for 800 ms, followed by 200 ms by the target stimulus, whose offset was
determined by the subject’s response. Pictures were selected from the International Affective
Picture System (IAPS).
Results
In the word-evaluation task, a happy word was classified significantly faster and more accurately
if it was preceded by a major chord, or a high register chord, whereas reaction times were significantly
slower if it was preceded by a low register chord. Happy words and pictures were classified
faster than sad words and pictures. In the picture-evaluation task happy and pleasant pictures were
evaluated faster if the prime was a high register chord; sad and unpleasant pictures were evaluated
faster if the prime was a low register chord (congruent pairs). In incongruent pairs reaction times
were significantly slower. In the picture-evaluation task mode and consonance of prime chords did
not influence reaction times, whereas register did.
Conclusion The affective content of musical chords, as results from their mode, consonance,
and register significantly influence cognitive non-musical tasks such a picture- or word-evaluation
task. This means that affective properties of musical stimuli are shared with ongoing mental
processes. These results can contribute to explain the Mozart’s effect, i.e. the influence of musical
stimuli to concomitant cognitive tasks. Mode, consonance, and register are not equally effective in
influencing the evaluation task. As regard to mode major chords were more effective than minor
chords (also Mozart’s effect is found for major excerpts and not for minor ones). Register was
more effective than mode. Since the picture-evaluation task implies more bottom-up processes
than the word-evaluation task, it was less influenced by the affective content of priming chords.
Key words: Affective priming, Emotion, Mode, register, consonanc
Papillomatosi recidivante respiratoria. Possibilità della terapia interferonica
No full textObiettivo. La papillomatosi respiratoria recidivante (RRP) è una patologia delle alte e basse vie respiratorie la cui ormai comprovata etiopatogenesi virale per diverso tempo ha costituito materia di studio per molti ricercatori e nel contempo ha rappresentato una sfida per quanto riguarda la programmazione terapeutica, che da sempre ha dovuto fare i conti con la irriducile tendenza alla recidiva di questa affezione. Distinta in due entità cliniche, «juvenile onset» e «adult onset» a seconda dell’età di insorgenza e delle differenti caratteristiche di estrinsecazione clinica, pur potendosi collocare fra le affezioni benigne, essa espone i soggetti affetti ad un vero e proprio calvario terapeutico costituito da interventi chirurgici, spesso ripetuti per la già citata tendenza a recidivare, e da terapie di supporto medico, che a vario titolo e con differenti risultati, tentano di risolvere o perlomeno attenuare il problema costituito dalla inesauribile spinta replicativa virale.
Metodi. Gli Autori, sulla base della loro esperienza, propongono uno schema terapeutico basato sull’utilizzo dell’esclusiva terapia interferonica, cui candidare soggetti affetti da RRP a localizzazione laringea con caratteristiche ben definite: diffusione laringea non massiva, tale da non richiedere l’ausilio della tracheotomia, e buone condizioni generali tali da consentire la pratica della terapia interferonica, non sempre scevra da effetti collaterali importanti.
Risultati. Lo proposta terapeutica degli Autori, applicata a soggetti affetti da RRP, scelti dopo una valutazione accurata, in prima istanza ha dimostrato di poter perlomeno differire l’utilizzo della terapia chirurgica, consentendo in questo modo di evitare la disseminazione nell’albero respiratorio delle particelle virali indotta sia dall’intubazione che dalla vaporizzazione provocata dal laser.
Conclusioni. Lo schema di terapia interferonica per la cura delle lesioni laringee indotte dalla RRP presenta delle indicazioni limitate sia dalle caratteristiche del farmaco, che dal tipo di lesioni da trattare, che devono avere caratteristiche ben precise; presenta altresì indubbi vantaggi rappresentati dalla possibilità di far regredire le lesioni papillomatose, mantenere sotto controllo la spinta replicativa virale, e nel contempo evitare alcune problematiche presentate dalla terapia chirurgica
Isolasi Senyawametabolit Sekunder dari Ekstrak Etanol Daun kayu Bitti (vilex cofassus) dan Uji Bioaktifitas Anti Bakteri Terhadap Staphylocossus Aureus & Esericia Coli
No full textIndonesia memiliki berbagai macam jenis tumbuhan yang dapat dijadikan sebagai obat tradisional. Salah satunya tanaman yang ada di Sulawesi Selatan yaitu tanaman daun kayu bitti dapat dijadikan sebagai obat penghilang bau badan. Penelitian ini bermaksud untuk mengidentifikasi senyawa metabolit sekunder ekstrak etanol daun kayu bitti dengan metode maserasi. Sebanyak ± 2 kg serbuk daun kayu bitti dimaserasi dengan pelarut etanol kemudian dievaporasi menggunakan alat evaporator menghasilkan ekstrak kental sebanyak 209,5828 gram. Ekstrak kental di uji fitokimia menghasilkan senyawa alkaloid dan falvonoid.
Hasil pemisahan dengan kromatografi kolom cair vakum diperoleh 17 fraksi. Dari 5 fraksi gabungan, fraksi A terbentuk kristal kemudian di lakukan karakterisasi dengan alat FTIR dan dilakukan uji bioaktivitas antibakteri terhadap bakteri Staphylococcus aureus dan Escherichia coli. Hasil analisis FTIR diperoleh serapan gugus N-H, C-H, dan C=O yang diduga merupakan senyawa jenis alkaloid. Uji aktivitas antibakteri ekstrak etanol daun kayu bitti dapat menghambat pertumbuhan bakteri Staphylococcus aureus tetapi tidak menghambat pertumbuhan bakteri Escherichia coli. Sedangkan uji isolate murni tidak berpengaruh terhadap bakteri uji yang digunakan
Bayesian Mendelian Randomization for incomplete pedigree data, and the characterisation of Multiple Sclerosis proteins
No full textBefore the GWAS (genome-wide association study) era, many genetic determinants of disease were found via analysis of multiplex pedigrees, that is, by looking for genetic markers that run in families in a similar way as disease. GWAS advent has robbed pedigree analysis
of its luster. Future scientific methodology seesaw might bring pedigree analysis back into the spotlight. After the recent discovery of hundreds of disease-associated variants, interest is focusing on the way these variants affect downstream molecular markers, such as transcripts and protein levels, and on the way the resulting changes in these markers in turn affect disease risk. Statistical methods such as Mendelian Randomization (Katan, 1986), hereafter denoted as MR, represent important tools in this effort. Most MR studies are based on data from unrelated individuals, a notable exception being Brumpton et al. (2019). In the present paper we argue that by enriching these data with data from family-related individuals, a number of difficulties that are encountered in MR can be signicantly attenuated. Motivated by the above considerations, this paper discusses extensions of MR to deal with pedigree data. We adopt the Bayesian MR framework proposed by Berzuini and colleagues (Berzuini et al., 2018), and extend it in various ways to deal with pedigree data
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