2,236 research outputs found

    The indexing at the Internet

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    An analysis of the presence of indexing on the Internet is presented, supported by the idea that an important part of this network of computers is based or it is impregnated in higher or lower degree by indexing. The indexing pillars are the metadata, the search engines, the users and the web positioning. Each one of these four elements is reviewed to prove the above approach, the one that we name the Indexing Web universe

    Nutraceuticals and diet in human health and disease. The special issue at a glance

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    This first Special Issue collects fifteen original research and up-to-date review articles addressing the beneficial properties of herbal products, nutrient supplements, dietary regimens, and functional food for the complementary therapy of human pathologies. In these articles, renowned scholars present and discuss the curative effects and the molecular mechanisms of action of nutraceuticals, medicinal herbs, and dietary regimens that have been proven effective in the treatment of cancers, metabolic syndrome, fatty liver disease, hearth arrythmia and neurodegenerative disorders

    Isidoro e la tradizione grammaticale

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    La produzione di Isidoro viene inserita in una precisa tradizione patristica di osservanza grammaticale. In particolare, l'osservanza o meno della grammatica finisce per testimoniare il complesso rapporto con i classici pagani per i letterati cristiani. La personalità di Isidoro dal canto suo mostra di recepire i dati dell'antica dialettica, che ripropone per scrupolo anche quando si rivela in realtà completamente superate le riserve nei confronti della letteratura degli auctores

    San Isidoro Basilica , c. 1160, south side, right portal, Romanesque, Leon, Spain

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    San Isidoro Basilica (aka the Royal Collegiate Church of St. Isidore of Seville), c. 1160, South side, which is the main entrance of San Isidoro; view of right portal. Romanesque, Leon, Spain.https://digital.kenyon.edu/peregphotos/3400/thumbnail.jp

    Isidoro Ocampo, El Facismo

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    Isidoro Ocampo, El Facismo; Image of a murdered Jew, tied to a post with Swastikas, color lithograph, 47 x 67.5 c

    San Isidoro Basilica, c. 1160, south side, left portal tympanum sculpture, Romanesque, Leon, Spain

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    San Isidoro Basilica (aka the Royal Collegiate Church of St. Isidore of Seville), c. 1160, South side, which is the main entrance of San Isidoro; the west end was built against the Roman city wall, left portal tympanum sculpture, Romanesque, Leon, Spain.https://digital.kenyon.edu/peregphotos/1151/thumbnail.jp

    San Isidoro Basilica , c. 1160, south side, which is the main entrance, Romanesque, Leon, Spain

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    San Isidoro Basilica (aka the Royal Collegiate Church of St. Isidore of Seville), c. 1160, South side, which is the main entrance of San Isidoro; the west end was built against the Roman city wall.ote sculpture of Santiago Matamoros at the roofline above the left doorway. Romanesque, Leon, Spain.https://digital.kenyon.edu/peregphotos/1114/thumbnail.jp

    A fast and simple method for simultaneous mixed site-specific mutagenesis of a wide coding sequence.

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    Site-specific mutagenesis at one or multiple sites has recently become an invaluable strategy in functional proteomic studies and genetic engineering.We describe a novel PCR-based procedure for site-specific mutagenesis that permits in a single-step all three types of nucleotide sequence mutation (deletion, insertion and substitution).The entire procedure is carried out in one tube and takes about 3 to 4 h. The method utilizes two primers, one of which is phosphorylated at the 5'-terminus, that are designed to directly anneal back-to-back to the target sequence inserted in a plasmid. For deletion type of mutagenesis (of virtually no limits of extent), primers anneal at the ends of the sequence to be deleted. For insertion and substitution types of mutagenesis, the primers bear the mutagenic sequences in a tail. The entire circular plasmid, here tested for a maximum length of 7 kbp, is amplified by inverse PCR. The PCR product incorporates the desired mutagenesis and, after ligation, the plasmid is ready for cloning in bacteria.The method has been proved very efficient to delete up to 279 nucleotides, to introduce simultaneously deletions, insertions and substitutions and to perform the alanine-scanning in a wide coding region. The procedure is suitable for applications in gene engineering and for construction of libraries

    San Isidoro Basilica , c. 1160, south side, right portal, bottom of tympanum, Romanesque, Leon, Spain

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    San Isidoro Basilica (aka the Royal Collegiate Church of St. Isidore of Seville), c. 1160, South side, which is the main entrance of San Isidoro; the west end was built against the Roman city wall, right portal, bottom of tympanum. Note wonderful monster figures that dip into the doorway. Romanesque, Leon, Spain.https://digital.kenyon.edu/peregphotos/3150/thumbnail.jp
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