158 research outputs found
“Didattica a distanza: implicazioni didattiche, psicologiche e prospettive”
No full textLa pandemia COVID-19 ha portato l’intera popolazione mondiale ad affrontare difficoltà sociali, sanitarie ed economiche. Dopo circa due anni di pandemia, sono stati pubblicati numerosi articoli di ricerca e di opinione sulla salute mentale durante un periodo così difficile e, in particolare, sulle questioni didattiche e psicologiche riguardanti la scuola e l’istruzione in generale. Migliaia di studenti non solo delle scuole di ogni ordine e grado sono rimasti a casa senza alcuna interazione sociale, a causa delle misure di contenimento del contagio. Tali provvedimenti però hanno generato difficoltà che si potrebbero manifestare nel tempo con diverse ricadute sulla percezione del senso di comunità e sulle abilità di apprendimento e di interazione sociale.
Questo lavoro propone un’analisi critica sulle ricadute della pandemia in ambito scolastico e, in particolare, pone l’attenzione verso le conseguenze sull’apprendimento, sulla condizione psicologica di studenti ed insegnanti e sulle iniziative e progetti sviluppati e attuati per prevenire il disagio psicologico e supportare tali categorie. A tal fine sono stati analizzati gli studi focalizzati sulle implicazioni didattiche e sulla salute mentale delle persone appartenenti all’ambiente scolastico in diversi Paesi del mondo con particolare riguardo all’Italia
Mental Health and COVID-19: An Action Plan
No full textSince January 2020, the disease caused by the SARS-CoV-2 virus has spread and become pandemic. In a few months, the virus had seriously affected the health systems of various countries of the world and placed people in difficult psychological conditions. This manuscript briefly reviews COVID-19’s studies focused on psychological reactions to the event. Furthermore, this work presents a plan to easily frame the priorities of mental health areas related to COVID-19 which should be disseminated and that should be known by all health professionals and also by the major administrators of public health to empower the actual situation and prevent future emergencies. Today psychological COVID-19’s sequelae affected a great number of people in the world and also called “Long COVID” presents
psychological symptoms that affect for a long time people diagnosed as COVID. Due to this experience, it seems advisable to rethink the organization of mental health services to better help the population in case of serious alert for life
Assessment of mercury dispersal in a bandoned mining area by soil and lichen analysis
No full textThe total Hg content in soil and in the epiphytic lichen Parmelia sulcata was determined in a former cinnabar mining area on Mt. Amiata. Metal concentrations in soil and in lichen are significantly related and decrease at increasing distances from the zone most affected by minespoil and by air which is still vented from mine shafts. On the basis of these results and of Al analysis, it seems likely that anomalous Hg content in Mt. Amiata lichens is mainly due to the out-gassing of volatile Hg from soil, from vegetation and, in the most heavily polluted zone, to the air from mine shafts. © 1987 D. Reidel Publishing Company
Intracellular anion fluorescence assay for sodium/iodide symporter substrates
No full textThe sodium/iodide symporter (NIS) is primarily responsible for iodide accumulation in the thyroid gland for the synthesis of thyroid hormones; however, it can also transport other lyotropic anions in the thyroid gland and nonthyroid tissues. Some NIS substrates have important physiological or clinical roles, and others are environmental contaminants with health-related consequences. The aim of this study was to assess the utility of a yellow fluorescent protein variant, YFP-H148Q/I152L, as a biosensor to monitor the cellular uptake of NIS substrates, including thiocyanate (SCN-), nitrate (NO3-), chlorate (ClO3-), perchlorate (ClO4-), and perrhenate (ReO4-). The fluorescence of purified YFP-H148Q/I152L was suppressed by anions with an order of potency of ReO4- > ClO4- = I- = SCN- = ClO3- > NO3- ≫ Cl-. Anions also suppressed the fluorescence of YFP-H148Q/I152L expressed in FRTL-5, a thyroid cell line with high NIS expression. Quantitation of intracellular concentrations revealed differences among anions in the affinity and maximal velocity of NIS-mediated uptake as well as in the rate constant for passive efflux. These results suggest that YFP-H148Q/I152L can serve as an intracellular biosensor of NIS-transported anions and may be useful to study the physiology of endogenous anions as well as the health-related consequences of environmental anions
TSHR (thyroid stimulating hormone receptor)
No full textReview on TSHR (thyroid stimulating hormone receptor), with data on DNA, on the protein encoded, and where the gene is implicated
Comparação do nível de implementação do princípio da IOSCO “a regulação deve promover a transparência das negociações” na União Europeia e na Colômbia
No full textThis article assesses and compares the level of implementation of the IOSCO principle concerning trading transparency in the regulatory framework of the European Union and Colombia. For that purpose, the author applies the methodology set by IOSCO, so as to assess the level of implementation of the referred principle in the regulatory framework of the mentioned jurisdictions. Nonetheless, the scope of the research is narrow to the study of the level of trading transparency of the transactions executed in the stock exchange.Este artículo evalúa y compara el grado de implementación del principio IOSCO en relación con la transparencia del intercambio en el marco regulatorio de la Unión Europea y de Colombia. Con tal fin, el autor aplica la metodología establecida por IOSCO para evaluar el grado de implementación del principio mencionado en el marco regulatorio de las jurisdicciones mencionadas. Sin embargo, el alcance de la investigación es limitado para estudiar el grado de transparencia de los intercambios ejecutados en la bolsa de valores.Este artigo avalia e compara o grau de implementação do princípio da IOSCO relacionado à transparência das negociações no marco regulatório da União Europeia e da Colômbia. Para tanto, o autor aplica a metodologia estabelecida pela IOSCO, de forma a avaliar o nível de implementação do referido princípio nos marcos regulatórios das jurisdições mencionadas. Contudo, o escopo da pesquisa é limitado ao estudo do nível de transparência das negociações realizadas na bolsa de valores
Comparison of the Level of Implementation of the IOSCO Principle “Regulation Should Promote Transparency of Trading” in the European Union and Colombia
No full textThis article assesses and compares the level of implementation of the IOSCO principle concerning trading transparency in the regulatory framework of the European Union and Colombia. For that purpose, the author applies the methodology set by IOSCO, so as to assess the level of implementation of the referred principle in the regulatory framework of the mentioned jurisdictions. Nonetheless, the scope of the research is narrow to the study of the level of trading transparency of the transactions executed in the stock exchange.Este artigo avalia e compara o grau de implementação do princípio da IOSCO relacionado à transparência das negociações no marco regulatório da União Europeia e da Colômbia. Para tanto, o autor aplica a metodologia estabelecida pela IOSCO, de forma a avaliar o nível de implementação do referido princípio nos marcos regulatórios das jurisdições mencionadas. Contudo, o escopo da pesquisa é limitado ao estudo do nível de transparência das negociações realizadas na bolsa de valores.Este artículo evalúa y compara el grado de implementación del principio IOSCO en relación con la transparencia del intercambio en el marco regulatorio de la Unión Europea y de Colombia. Con tal fin, el autor aplica la metodología establecida por IOSCO para evaluar el grado de implementación del principio mencionado en el marco regulatorio de las jurisdicciones mencionadas. Sin embargo, el alcance de la investigación es limitado para estudiar el grado de transparencia de los intercambios ejecutados en la bolsa de valores
A global regulatory framework for transnational securities markets
No full textPhDDevelopments in the investment securities markets have played an important role in the growth and globalization of the world’s financial markets. Securities market participants, investment banks and hedges funds in particular, were also in the epicentre of the global financial crisis 2007~2010 (GFC). The globalization-to-crisis process has highlighted the problems of regulating the globalizing transnational securities markets on the basis of national laws alone. More precisely, the three global-level problems in securities regulation are: regulatory divergence and conflicts, gaps in cross-border supervision, and, spill-over of systemic risks.
This thesis contributes to the post-GFC regulatory reforms debate by establishing the concept of a Global Regulatory Framework (GRF). The GRF consists of a flexible governance structure within which national regulators and policy makers may interact with counterparts, either directly or through regional and global bodies, in seeking to address cross-border or substantive issues of securities regulation. The GRF also comprises a framework of tools for regulatory and supervisory cooperation, using which solutions could be reached for the global-level problems.
The GRF is essentially soft law by nature. As a result, while the structure and mechanisms provided by the GRF contribute to securities market efficiency and stability, national sovereignty is also duly upheld. The problems of implementation and legitimacy pertaining to soft law processes are addressed, with recommendations for an implementation structure and principles of ex ante participation and transparency developed.
The thesis comprises three Parts, with two Chapters in each, followed by a seventh Chapter of overall Conclusions. Starting from the analysis of the three global-level regulatory problems in the fast globalizing securities markets, the thesis builds on the experience from the EU and US, and other global actors, including the IMF, FSB and IOSCO, to produce a multi-layered structure for the governance of the securities markets. The GRF is designed to accommodate and engender different functions and forms of collective actions, because flexibility is crucial for addressing new cross-border issues arising from the often turbulent transnational securities markets
The Financial Crisis and the Regulation of Credit Rating Agencies : A European Banking Perspective
No full textCredit rating agencies (CRAs) bear some responsibility for the financial crisis that started in 2007 and remains ongoing. This is acknowledged by policymakers, market participants, and by the agencies themselves. It soon became clear that, given the depth of the crisis, CRAs would not be able to satisfy policymakers by eliminating flaws in their rating methods and improving corporate governance. Although the CRAs were more or less unregulated before the outbreak of the financial crisis, after the crisis started, politicians became increasingly vocal in demanding regulation. Initially, these demands were confined to a more binding form of self-regulation. But as the crisis progressed, the calls for state regulation grew ever louder. It became apparent after the November 2008 G-20 summit in Washington that state regulation could no longer be avoided. In Europe, the course had been set in this direction even before then. Since European policymakers saw the crisis as evidence that the Anglo-Saxon approach to the financial markets had failed, they believed they were now strongly placed to have a decisive influence on shaping a new international financial order. It is remarkable to note the shift in European policy from a self-regulatory approach, which was comparatively liberal in international terms, to quite rigorous state regulation of CRAs. Both the European Commission and the European Parliament drew up far-reaching plans. Although European policymakers knew that only globally consistent regulation would be appropriate for a new world financial order, their initial draft legislation was geared more toward stand-alone European regulation. While the final version of the European Union Regulation on Credit Rating Agencies focuses firmly on the European arena, the key point for all market participants is that this is unlikely to have an adverse effect on the global ratings market. It must nevertheless be recognized that the scope of the selected regulatory approach is extremely narrow. Certainly, it has the potential to improve the corporate governance of CRAs and prevent conflicts of interests. But it can do nothing to address the repeated calls for greater competition or for CRAs to be made liable for their ratings.credit rating agencies, financial crisis, financial regulation, European Regulation
The Financial Crisis and the Regulation of Credit Rating Agencies: A European Banking Perspective
No full textCredit rating agencies (CRAs) bear some responsibility for the financial crisis that started in 2007 and remains ongoing. This is acknowledged by policymakers, market participants, and by the agencies themselves. It soon became clear that, given the depth of the crisis, CRAs would not be able to satisfy policymakers by eliminating flaws in their rating methods and improving corporate governance. Although the CRAs were more or less unregulated before the outbreak of the financial crisis, after the crisis started, politicians became increasingly vocal in demanding regulation. Initially, these demands were confined to a more binding form of self-regulation. But as the crisis progressed, the calls for state regulation grew ever louder. It became apparent after the November 2008 G-20 summit in Washington that state regulation could no longer be avoided. In Europe, the course had been set in this direction even before then. Since European policymakers saw the crisis as evidence that the Anglo-Saxon approach to the financial markets had failed, they believed they were now strongly placed to have a decisive influence on shaping a new international financial order. It is remarkable to note the shift in European policy from a self-regulatory approach, which was comparatively liberal in international terms, to quite rigorous state regulation of CRAs. Both the European Commission and the European Parliament drew up far-reaching plans. Although European policymakers knew that only globally consistent regulation would be appropriate for a new world financial order, their initial draft legislation was geared more toward stand-alone European regulation. While the final version of the European Union Regulation on Credit Rating Agencies focuses firmly on the European arena, the key point for all market participants is that this is unlikely to have an adverse effect on the global ratings market. It must nevertheless be recognized that the scope of the selected regulatory approach is extremely narrow. Certainly, it has the potential to improve the corporate governance of CRAs and prevent conflicts of interests. But it can do nothing to address the repeated calls for greater competition or for CRAs to be made liable for their ratings.regulation credit rating agencies; europe credit rating agency; european bank financial crisis; financial crisis; credit rating agency
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