32 research outputs found

    Antecedents of the Idea of Human Rights: A Survey of Perspectives

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    human development, human rights

    The meaning and experience of participation in stroke survivors.

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    In the UK, one in four men and one in five women will be expected to have experienced a stroke by the time they are eighty five (Daniel, Wolfe, Busch, & McKevitt, 2009). Medical advancements which make survival more likely mean that there is a growing population of people living with the long term impact of stroke. The success of rehabilitation was traditionally judged by functional ability and coping with everyday tasks. The inclusion of the term ‘participation’, in the ICF (World Health Organisation, 2001) represents a shift in healthcare and research to a more holistic view of rehabilitation. Pre-defined measures of participation may not capture subjective experience, and little research exists which investigates participation in stroke survivors from a patient perspective. This research aimed to explore the meaning and experience of participation in stroke survivors. These aims required the collection of deep, rich data, from a small sample of participants. A qualitative methodology was therefore needed, and Interpretive Phenomenological Analysis was identified as an appropriate approach by which to find the underlying essences of a multiplicity of experiences. The central themes within the findings were ‘meaning’ and ‘experience’. ‘Meaning’ included the sub-themes ‘being actively involved’, ‘making meaningful choices’ and ‘being me’. ‘Being me’ described the relationship between self-identity, role and participation, which has not previously been explored in relation to stroke. Sub-themes of ‘experience’ were ‘acceptance’, ’coping’ and ‘new participation’. The findings suggest that each stroke survivor has a unique experience of participation, therefore individualised approaches to rehabilitation may be most effective. Future research should include exploring the link between participation and self-identity in stroke survivors, in order to build on our understanding of the link between participation and self-identity in relation to stroke

    Celebrity culture and public connection: bridge or chasm?

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    Media and cultural research has an important contribution to make to recent debates about declines in democratic engagement: is for example celebrity culture a route into democratic engagement for those otherwise disengaged? This article contributes to this debate by reviewing qualitative and quantitative findings from a UK project on 'public connection'. Using self-produced diaries (with in-depth multiple interviews) as well as a nationwide survey, the authors argue that while celebrity culture is an important point of social connection sustained by media use, it is not linked in citizens' own accounts to issues of public concern. Survey data suggest that those who particularly follow celebrity culture are the least engaged in politics and least likely to use their social networks to involve themselves in action or discussion about public-type issues. This does not mean 'celebrity culture' is 'bad', but it challenges suggestions of how popular culture might contribute to effective democracy

    Feasibility study of the effects of art as a creative engagement intervention during stroke rehabilitation on improvement of psychosocial outcomes:study protocol for a single blind randomized controlled trial: the ACES study

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    BACKGROUND: Benefits of art participation after stroke are becoming increasingly recognized. Qualitative studies suggest that participation in visual arts creative engagement interventions (CEIs) during rehabilitation after stroke may improve mood, self-esteem, hope and some aspects of physical recovery. This study examines the feasibility of undertaking a randomized controlled trial of a CEI delivered by artists within in-patient stroke rehabilitation to test effectiveness.METHODS/DESIGN: This trial is a two arm, single-blind, randomized controlled feasibility trial within in-patient stroke rehabilitation. We will recruit 80 patients receiving stroke rehabilitation in two stroke units in a health board area of Scotland (40 patients in each arm). Intervention arm participants will receive a visual-arts based CEI facilitated by experienced artists. Artists will follow an intervention protocol with specific components that enable participants to set, achieve and review artistic goals. Participants will receive up to eight intervention sessions, four within a group and four one-to-one with the artist. Control group participants will receive usual care only.Data collection will occur at baseline, post-intervention and three-month follow-up. Stroke-related health status is the primary outcome; mood, self-esteem, self-efficacy, perceived recovery control and hope are secondary outcomes. Semi-structured interviews will be conducted with purposively selected patients, artists and healthcare staff to elicit views and experiences of the intervention and feasibility and acceptability of trial processes. Recruitment rates, retention rates and patient preference for art participation will also be collected. Data will indicate, with confidence intervals, the proportion of patients choosing or refusing participation in the CEI and will allow calculation of recruitment rates for a future definitive trial. Summary data will indicate potential variability, magnitude and direction of difference between groups. Findings will inform sample size calculations for a definitive trial. Thematic analysis of qualitative data will be managed using the Framework Approach. Framework is an analytical approach for qualitative data, commonly used in policy and medical research.DISCUSSION: If shown to demonstrate effects, this intervention has the potential to address aspects of stroke recovery previously. Not routinely addressed in rehabilitation.TRIAL REGISTRATION: Registered with Clinical Trials.Gov: NCT02085226 on 6th March 2014.</p

    The use of email as a component of adult stammering therapy : a preliminary report

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    In West Glasgow email has evolved from a rapid means of arranging therapy appointments with adults who stammer into a medium for exchange of therapeutic messages with some clients. Since 2004, sixteen clients have used email to communicate as part of their therapy programme. The benefits include improving access to services, supporting speech change, facilitating lasting personal growth, improving clinical decision-making, equalizing the therapist-client relationship and enhancing caseload management. Although this experience suggests that email is appropriate for stammering therapy, the effectiveness and ethics of, and the rationale for, clinical practice that includes email need careful consideration. Further research is required to formally evaluate the client experience

    Chemical, Spectroscopic Characterization And Antibacterial Activities In Vitro Of A Novel Gold(i)-ibuprofen Complex

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    A novel gold(I) complex with ibuprofen was synthesized and characterized by chemical and spectroscopic measurements. Elemental analysis led to the composition AuC14H18O2N. Infrared, 1H and 13C NMR data suggest coordination of the ligand to Au(I) through the oxygen atom of the carboxylic group in a monodentate form. An antibiotic sensitive profile indicated antibacterial activity in vitro of the complex against Gram-negative (E. coli and P. aeruginosa) and Gram-positive (S. aureus) microorganisms. © 2010 Elsevier B.V. All rights reserved.145738740Sadler, P.J., Sue, R.E., The chemistry of gold drugs (1994) Met.-Based Drugs, 1, pp. 107-144Fricker, S.P., Metal based drugs: From serendipity to design (2007) Dalton Transactions, (43), pp. 4903-4917. , DOI 10.1039/b705551jYoun, H.S., Lee, J.Y., Saitoh, S.I., Miyake, K., Hwang, D.H., Auranofin, as an anti-rheumatic gold compound, suppresses LPS-induced homodimerization of TLR4 (2006) Biochemical and Biophysical Research Communications, 350 (4), pp. 866-871. , DOI 10.1016/j.bbrc.2006.09.097, PII S0006291X06021462Fox, C.L., Modak, S.M., Mechanism of silver sulfadiazine action on burn wound infections (1974) Antimicrob. Agents Chemother., 5, pp. 582-588Elsome, A.M., Hamilton-Miller, J.M.T., Brumfitt, W., Noble, W.C., Antimicrobial activities in vitro and in vivo of transition element complexes containing gold(I) and osmium(VI) (1996) Journal of Antimicrobial Chemotherapy, 37 (5), pp. 911-918. , DOI 10.1093/jac/37.5.911Corbi, P.P., Quintão, F.A., Ferraresi, D.K.D., Lustri, W.R., Amaral, A.C., Massabni, A.C., Chemical, spectroscopic characterization, and in vitro antibacterial studies of a new gold(I) complex with N-acetyl-L-cysteine (2010) J. Coord. Chem., 63, pp. 1390-1397Abbehausen, C., Heinrich, T.A., Abrão, E.P., Costa-Neto, C.M., Lustri, W.R., Formiga, A.L.B., Corbi, P.P., Chemical, spectroscopic characterization, DFT studies and initial pharmacological assays of a silver(I) complex with N-acetyl-l-cysteine (2011) Polyhedron, 30, pp. 579-583Cavicchioli, M., Massabni, A.C., Heinrich, T.A., Costa-Neto, C.M., Abrão, E.P., Fonseca, B.A.L., Castellano, E.E., Leite, C.Q.F., Pt(II) and Ag(I) complexes with acesulfame: Crystal structure and a study of their antitumoral, antimicrobial and antiviral activities (2010) J. Inorg. Biochem., 104, pp. 533-540El-Gamel, N.E.A., The interactions of metal ions with nonsteroidal anti-inflammatory drugs (oxicams) (2009) J. Coord. Chem., 62, pp. 2239-2260Defazio, S., Cini, R., Synthesis, X-ray structural characterization and solution studies of metal complexes containing the anti-inflammatory drugs meloxicam and tenoxicam (2003) Polyhedron, 22, pp. 1355-1366Kovala-Demertzi, D., Transition metal complexes of diclofenac with potentially interesting anti-inflammatory activity (2000) Journal of Inorganic Biochemistry, 79 (1-4), pp. 153-157. , DOI 10.1016/S0162-0134(99)00175-0, PII S0162013499001750Harrak, Y., Casula, G., Basset, J., Rosell, G., Plescia, S., Raffa, D., Cusimano, M.G., Pujol, M.D., Synthesis, anti-inflammatory activity, and in vitro antitumor effect of a novel class of cyclooxygenase inhibitors: 4-(Aryloyl)phenyl methyl sulfones (2010) J. Med. Chem., 53, pp. 6560-6571Zawidlak-Wegrzynska, B., Kawalec, M., Bosek, I., Luczyk-Juzwa, M., Adamus, G., Rusin, A., Filipczak, P., Kurcok, P., Synthesis and antiproliferative properties of ibuprofeneoligo(3- hydroxybutyrate) conjugates (2010) Eur. J. Med. Chem., 45, pp. 1833-1842Nakamoto, K., (1997) Infrared and Raman Spectra of Inorganic and Coordination Compounds, Part B, , fifth ed. John Wiley & Sons New YorkBauer, A.W., Kirby, W.M., Sheris, J.C., Turck, M., Antibiotic susceptibility testing by a standardized single disk method (1966) Am. J. Clin. Pathol., 45, pp. 493-496Clinical, L., (2007) Performance Standards for Antimicrobial Susceptibility TestingSeventeenth Informational Supplement, , Wayne, PA USALemaire, S., Glupczynski, Y., Duval, V., Joris, B., Tulkens, P.M., Bambeke, F.V., Activities of ceftobiprole and other cephalosporins against extracellular and intracellular (THP-1 macrophages and keratinocytes) forms of methicillin-susceptible and methicillin-resistant Staphylococcus aureus (2009) Antimicrob. Agents Chem., 53, pp. 2289-2297Nomiya, K., Noguchi, R., Ohsawa, K., Tsuda, K., Oda, M., Synthesis, crystal structure and antimicrobial activities of two isomeric gold(I) complexes with nitrogen-containing heterocycle and triphenylphosphine ligands, [Au(L)(PPh3)] (HL = pyrazole and imidazole) (2000) J. Inorg. Biochem., 78, pp. 363-37

    Teacher appraisal : the impact of observation on teachers’ classroom behaviour

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    This thesis is based on three English language teacher case studies located in the Middle East where classroom discourse has been analysed in order to establish the impact that an appraisal observer has on teachers‘ behaviour. The literature suggests that the presence of an observer alters events in the classroom, but to date there has not been any research into the nature of these changes which draws on transcripts of observed lessons. Each teacher recorded a model (observed) and a pedagogic (non–observed) lesson with similar parameters so that they could be compared, and commonalities and differences identified. The teachers were then interviewed in order to establish their understanding of the salient features of appraisal observations, as were three supervisors responsible for observing teachers in similar contexts. Transcripts of the lessons were analysed using SETT (Walsh, 2006), and the interview data was also transcribed and evaluated. The results indicate that there are significant differences between model and pedagogic lessons in terms of the external factors (planning, sequencing, interaction, amount of administration, student use of L1). However, the internal factors (the features of ongoing verbal interaction between teacher and students in the classroom) remain fundamentally the same whether or not an observer is present, although the teacher demonstrates greater control in a model lesson. By analysing transcripts of classroom interaction, this research indicates what happens in the classroom when teachers are being observed, providing data to confirm existing claims about observer effects, and suggesting that the learner role is greater than originally thought. The importance of observer training is identified, as well as the need for a fundamental review of observation, encompassing all parties involved, if it is to be a true reflection of the classroom behaviour of the teacher being observed
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