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    A Strategy For The Development Of The Medical Devices National Innovation System [uma Estratégia De Desenvolvimento Para O Sistema Nacional De Inovação De Produtos Médicos]

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    This paper presents a proposal of a program for the development of the Brazilian National Innovation System for Medical Products (SNIPM) under the National Health System (SUS) integrated and aligned with the actions of the Brazilian Ministry of Health. Clinical engineering knowledge and tools allowed performing a differentiated socio-economic analysis of the sector, the systematization and the perception of actors and factors that induce or retard the growth of the technology sector. In this article, the medical devices sector in Brazil was first contextualized to in the light of current national and global socio-economic conjuncture, in order to characterize it as a major inducer of innovative activities. The definitions and theories about the National Innovation Systems are described, followed by a discussion of the specifics of SNIPM in Brazil, with its actors, including their duties and responsibilities. The methodology for the collection and analysis of economic data, were shown, in order to characterize the importance of this sector to the national economy and its potential to induce the rising of innovative technologies whithin the SNIPM. The analysis of industry data is presented, which attempts to present and comment on some industry data collected during a survey. In the Results section, it is presented the design of a program used to to catalyze the development of the SNIPM considering the technological demands and priorities of the SUS and the target markets of the productive sector. The proposed program, which was developed and implemented within the Brazilian Ministry of Health, can become one of the tools within the SUS to strengthen and modernize the sector of medical equipments and materials, aiming to increase the innovative capacity of firms and change its competitive standing.282124139Albuquerque, E.M., Cassiolato, J.E., As especificidades do sistema de inovação do setor saúde (2002) Revista de Economia Política, 22 (4), pp. 134-151Arruda, M., Velmulm, R., Hollanda, S., Inovação tecnológica no Brasil: A indústria em busca da competitividade global (2006) São Paulo: ANPEI, p. 117Bobbie, B., Health Technology assessment: Challenges and solutions for medical devices (2010) Canada: Cook MedicalRegula direitos e obrigações relativos à propriedade industrial (1996) Diário Oficial da República Federativa do Brasil, pp. 8353-8366. , Brasil. Lei n o 9.279, 14 de maio de. Brasília, DF, n. 93, 15 mai1996. Seção1Dispõe sobre a proteção da propriedade intelectual de programa de computador, sua comercialização no País, e dá outras providências (1998) Diário Oficial da República Federativa do Brasil, pp. 1-3. , Brasil. Lei n o 9.609, 19 de fevereiro de. Brasília, DF, n. 36, 20 fev1998. Seção1Dispõe sobre incentivos à inovação e à pesquisa científica e tecnológica no ambiente produtivo e dá outras providências (2004) Diário Oficial da República Federativa do Brasil, pp. 2-4. , Brasil. Lei n o 10.973, de2 de dezembro de. Brasília, DF, n. 233, 3 dez2004. Seção1Institui o Regime Especial de Tributação para a Plataforma de Exportação de Serviços de Tecnologia da Informação -REPES, o Regime Especial de Aquisição de Bens de Capital para Empresas Exportadoras-RECAP e o Programa de Inclusão Digital e dá outras providências (2005) Diário Oficial da República Federativa do Brasil, pp. 1-12. , Brasil. Lei n° 11.196, de21 de novembro de. Brasília, DF, n. 223, 22 nov2005. Seção1Dispõe sobre a classificação de produtos correlatos para efeito de registro no Ministério da Saúde (1993) Diário Oficial da República Federativa do Brasil, pp. 7042-7045. , Brasil. Ministério da Saúde. Portaria Conjunta SNVS/SAS n o 1, de17 de maio de. Brasília, DF, n. 98, mai1993. Seção1Departamento de Informática do SUS -DATASUS (2008) Sistema TABNET, , tabnet.datasus.gov.br/tabnet/tabnet.htm, Brasil. Ministério da Saúde. Sítio eletrônico. [acesso em 2008 fev.]. Disponível emTecnologia e Insumos Estratégicos (2008) Pesquisa para Saúde: Desenvolvimento e inovação para o SUS: Relatório final, , Brasil. Ministério da Saúde. Secretaria de Ciência, Brasília: Ministério da SaúdeInstitui, no âmbito do Sistema Único de Saúde-SUS, o Programa Nacional para Qualificação, Produção e Inovação em Equipamentos e Materiais de Uso em Saúde no Complexo Industrial da Saúde (2008) Diário Oficial da República Federativa do Brasil, p. 119. , Brasil. Ministério da Saúde. Portaria MS375, de29 de fevereiro de. Brasília, DF, n. 41, 29 fev2008c. Seção1Freeman, C., Japan: A new national system of innovation? (1988) Technical Change and Economic Theory, pp. 341-348. , In: London: Pinter PublishersGadelha, C.A.G., O complexo industrial da saúde e a necessidade de um enfoque dinâmico na economia da saúde (2003) Ciência & Saúde Coletiva, 8 (2), pp. 521-535. , http://dx.doi.1590/S1413-81232003000200015.org/10Leão, R., Oliveira, E.J.V., Albornoz, L.J.C., (2008) Estudo setorial-Setor de equipamentos e materiais de uso em saúde, , Brasília: Ministério da SaúdeMcDaniel, C., Gates, R., (2004) Pesquisa de marketing, p. 562. , São Paulo: Thomson LearningOliveira, E.J.V., Leão, R., Button, V.L.S.N., Nova abordagem para o Sistema Nacional de Inovação de Produtos Médicos (2008) Congresso Brasileiro de Engenharia Biomédica, pp. 335-338. , In: CBEB: Anais do 21 o2008Nov16-20Salvador, Brasil. Salvador2008Oliveira, E.J.V., Engenharia clínica aplicada à definição e implementação de uma proposta desenvolvimentista para o Sistema Nacional de Inovação de Produtos Médicos (2010) Campinas: Universidade Estadual de Campinas, , [dissertação](2010) Programa de Engenharia Biomédica-PEB. UFRJ, , http://www.peb.ufrj.br/pesquisa.htm, [Internet]. [acesso em 2010 maio]. Disponível emRosenberg, N., (1982) Inside the black box: Technology and economics, p. 320. , Cambridge: University PressWagner, C.S., Brahmakulam, I., Jackson, B., Wong, A., Yoda, T., Science and technology collaboration: Building capacity in developing countries? (2001) RAND: Arlington, , http://www.rand.org/pubs/monograph_reports/2005/MR1357.0.pdf, [Internet]. 2001 [cited 2012 Jan]. 102 p. Available from(2003) Medical device regulations: Global overview and guiding principles, p. 43. , World Health Organization-WHO. Genebr

    Projected Costs For Acquisition Of Equipment Ultrasound In Medical Clinics [projeção De Custos Para Aquisição De Equipamentos De Ultra-som Em Clínicas Médicas]

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    The objective of this work is to present a projection of costs for ultrasound scanning equipment acquisitions by medical imaging clinics and to understand how these acquisitions affect the final value of ease exam. In order to meet customer demands for the newest technology, medical imaging clinics substitute their equipments in shorter periods of time, trying to follow the launching of more sophisticated products. The cost of the anticipation of ultrasound scanning replacement was projected to verify how it affects the clinic budget. According to medical imaging clinics market profile, two factors of great importance in ultrasound scanning acquisition have been identified: the cost of tax loans paid and the monthly demand of imaging services. Medical imaging clinics seldom have the preoccupation to verify the impact of these factors in the equipment replacement, which may cause damage to their financial health. For this study data from 04 clinics, that have together 12 equipment acquisition processes in a given period, have been collected and analyzed. The clinics are located in the city of Campinas (SP, Brazil), which has a population greater than 1 million people. Each chosen clinic monthly makes, by ultrasound equipment, from 400 to 700 exams. The results showed that each exam costs from 1.00upto1.00 up to 7.22, just due to ultrasound scanning equipment acquisition. When the anticipation of medical equipment replacement was combined to the cost of tax loans paid and the monthly demand of imaging services, the projected cost of an imaging exam reached values between 1.00and1.00 and 20.00. © Springer-Verlag Berlin Heidelberg 2007.18816819Ewing, B.T., Kruse, J.B., Thompson, M.A., (2002) Linkages Within the Health Care Industry, , Texas: Texas Tech UniversityMartins, D.S., (2000) Custos e Orçamentos Hospitalares, , SP: ed. AtlasMartins, D.S., (2000) Custeio Hospitalar por Atividades, , SP: ed. AtlasAbbas, K., (2001) Gestão De Custos Em Organizações Hospitalares, , Tese de Mestrado, Depto de Engenharia de Produção, UFSC, SCAbreu, L.E., (2002) Avaliação de Projetos e Investimentos, , Fundação Getúlio VargasConsulta em site (dezembro/2005) - Cotação de fundo DI, , http://www.infomoney.com.br/cotacoes/mainoff.aspDenardin, A.A., (2004) A Importância Do Custo De Oportunidade Para a Avaliação De Empreendimentos Baseados Na Criação Do Valor Econômico, , em: ConTexto v4 no 6, Porto AlegreSuen, A.S., Metodologia para Avaliação do EVA (Economic Value Added) Através de Demonstrativos Financeiros e de Dados de Cotações de Preços, , SP: Ascent Financial Technologie

    Multichannel Arbitrary Waveform Beamformer Transmitter For Experimental Research Activities Of Ultrasound [beamformer De Transmissão Multicanal De Forma De Onda Arbitrária Para Atividades De Pesquisa Experimental Do Ultrassom]

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    This paper presents the development of a digital beamformer transmitter system for generation of arbitrary ultrasound waveforms, specifically designed for research purposes. The proposed architecture has 8 independent excitation channels and uses an FPGA device (Field Programmable Gated Array) for electronic control channel generation of ultrasonic acoustic beam transmission. The system allows operation in pulse-echo mode, with pulse repetition rate of excitation between 62.5 Hz and 8 kHz, or single pulse, center frequency between 500 kHz and 20 MHz, excitation voltage between -100 and +100 V, and individual control of amplitude apodization, phase angle and time delay trigger. The mathematical method for determining the digital signals of excitation is presented and validated through practical results for waveform generation with Gaussian profile and center frequency of 20 MHz, in a load formed by a 220 pF capacitor in parallel with a resistor of 1 kΩ. The results show that the proposed flexible and fully programmable architecture, can support the development of new algorithms and sophisticated processing techniques of the transmission beamformer.236667678(2010) Cyclone III Device Handbook I-II. Altera Handbook, , Altera Corporation, San Jose, CA USA(2007) High Speed Converter Evaluation Platform - HSC-ADC-EVALC, , Analog Devices Inc., Data sheet, Norwood, MA, USAAssef, A.A., Maia, J.M., Armstrong, R.B., Ashihara, H.M., Costa, E.T., Da Button, V.L.S.N., Sistema digital gerador de forma de onda arbitrária para aplicações de ultrassom (2010) XXII Congresso Brasileiro de Engenharia Biomédica (CBEB) - 2010, pp. 391-394. , Tiradentes MG BrasilAssef, A.A., Maia, J.M., Gewehr, P.M., Gamba, H.R., Costa, E.T., Button, V.L.S.N., Sistema para geração, aquisição e processamento de sinais de ultrasom (2009) Sba Controle & Automação, 20 (2), pp. 145-155Basoglu, C., Managuli, R., York, G., Kim, Y., Computing requirements of modern medical diagnostic ultrasound machines (1998) Parallel Computing, 24 (9-10), pp. 1407-1431. , PII S0167819198000647Bassi, L., Boni, E., Cellai, A., Dallai, A., Guidi, F., Ricci, S., Tortoli, P., A Novel Digital Ultrasound System for Experimental Research Activities. 11th Euromicro Conference on Digital System Design Architectures (2008) Methods and Tools, pp. 413-417Brown, J.A., Lockwood, G.R., A low-cost, high-performance pulse generator for ultrasound imaging (2002) IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 49 (6), pp. 848-851. , DOI 10.1109/TUFFC.2002.1009345Brunner, E., (2002) Ultrasound System Considerations and Their Impact on Front-end Components., , Application Note, Analog Devices, Norwood, MA, USAHuang, S.W., Li, P.C., Arbitrary waveform coded excitation using bipolar square wave pulsers in medical ultrasound (2006) IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 53 (1), pp. 106-116Hu, C.H., Zhou, Q., Shung, K.K., Design and implementation of high frequency ultrasound pulsed- wave doppler using FPGA (2008) IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 55 (9), pp. 2109-2111Jensen, J.A., Holm, O., Jensen, L.J., Bendsen, H., Nikolov, S.I., Tomov, B.G., Munk, P., Gammelmark, K.L., Ultrasound research scanner for real-time synthetic aperture data acquisition (2005) IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 52 (5), pp. 881-889Kim, Y., Kim, J.H., Basoglu, C., Winter, T.C., Programmable ultrasound imaging using multimedia technologies: A next-generation ultrasound machine (1997) IEEE Transactions on Information Technology in Biomedicine, 1 (1), pp. 19-29. , PII S1089777197035589Mahdy, E.R., Khalil, R.M., Sherif, S., Kadah, Y.M.K., FPGA based backend system for medical bmode ultrasound imaging (2006) Proc. Cairo International Biomedical Engineering Conference(2011) Medical Imaging: Ultrasound Imaging Systems, , Maxim Integrated Products, Application Note, Sunnyvale, CA, USAMisaridis, T., Jensen, J.A., Use of modulated excitation signals in ultrasound. Part I: Basic concepts and expected benefits (2005) IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 50, pp. 192-207(2007) Introduction to Phased Array Ultrasonic Technology Applications: R/D Tech Guideline, , Olympus NDT, Olympus NDT, MA, USAPark, J.H., Yoon, C., Chang, J.H., Yoo, Y., Song, T.K., A real-time synthetic aperture beamformer formedical ultrasound imaging (2010) IEEE Ultrasonics Symposium (IUS), pp. 1992-1995Ricci, S., Bassi, L., Boni, E., Dallai, A., Tortoli, P., Multichannel FPGA-based arbitrary waveform generator for medical ultrasound (2007) Electronics Letters, 43 (24), pp. 1335-1336. , DOI 10.1049/el:20072859Schneider, F.K., Agarwal, A., Mo Yoo, Y., Fukuoka, T., Kim, Y., A fully programmable computing architecture for medical ultrasound machines (2010) IEEE Transactions on Information Technology in Biomedicine, 14, pp. 538-540Silkdar, S., Managuli, R., Gong, L., A single mediaprocessor-based programmable ultrasound system (2003) IEEE Transactions on Information Technology in Biomedicine, 7, pp. 64-70(2009) MD2130 - High Speed Ultrasound Beamforming Source Driver, , Supertex Inc., Data sheet, Sunnyvale, CA, USA(2008) AFE5805 - Fully- Integrated, 8-channel Analog Front-end for Ultrasound, , Texas Instruments Inc., Data sheet, Dallas, Texas, USATomov, B.G., Jensen, J.A., Compact FPGA-based beamformer using oversampled 1-bit A/D converters (2005) IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 52 (5), pp. 870-880. , DOI 10.1109/TUFFC.2005.1503973Xu, X., Yen, J.T., Shung, K.K., A low-cost bipolar pulse generator for high-frequency ultrasound applications (2007) IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 54 (2), pp. 443-447. , DOI 10.1109/TUFFC.2007.259Zhou, S., Hossack, J.A., Dynamic-transmit focusing using time dependent focal zone and center frequency (2003) IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 50, pp. 142-15

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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