741 research outputs found

    Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients

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    There is strong interest in the nature of the neutralizing antibody response against SARS-CoV-2 in infected individuals. For vaccine development, it is especially important which antibodies confer protection against SARS-CoV-2, if there is a phenomenon called antibody-dependent enhancement (ADE) of infection, and if there is cross-protection by antibodies directed against seasonal coronaviruses

    Riflessioni linguistiche sul tedesco e sul russo in Julya Rabinowich: un confronto tra narrazione autobiografica orale e il romanzo Spaltkopf

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    Linguistic Reflections in German and Russian in Julya Rabinowich: A Comparative Study of Oral Autobiographical Narrative and the Novel Spaltkopf. The Austrian author Julya Rabinowich, born in Leningrad in 1970 to a family of Rus- sian Jews and emigrated to Vienna at the age of 7, is one of the most renowned repre- sentatives of contemporary literature in the German language. Rabinowich made her literary debut in 2008 with Spaltkopf (Split Head), her most strongly autobiographical novel. In 2012, the writer was interviewed by Michaela Bürger-Koftis as part of the research project Polyphonie. Mehrsprachigkeit_Kreativität_Schreiben. This interview can be understood as a linguistic biography, as Rabinowich recounts her experiences related to the languages in her linguistic repertoire, focusing particularly on German and Russian. From this account, the author’s Spracheinstellungen (linguistic attitudes), as well as the impressions and emotions related to her two main languages, emerge. The aim of this study is to compare the interview passages in which Rabinowich expresses herself regarding German and Russian with excerpts from Spaltkopf where the relationship of the protagonist, Mischka, with these two languages emerges. In this 162 Michaela Bürger-Koftis, Ramona Pellegrino way, it will be possible to determine whether Spaltkopf reflects not only the author’s migratory experience but also her linguistic biography. Furthermore, it will be analyz- ed if and to what extent the expression of linguistic attitudes and emotions related to German and Russian differs between the novel and the oral autobiographical account. To examine how Rabinowich expresses her linguistic experiences and emotions relat- ed to German and Russian, a qualitative analysis of the texts will be conducted, with a theoretical approach based on the concepts of linguistic biography and verbalization of emotions developed by Brigitta Busch and Reinhard Fiehler

    Ramona Bennett, Tacoma, October 1976

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    Ramona Bennett (b. 1938) is a prominent Puyallap Tribe leader and activist. She was elected to the Puyallup Tribal Council in 1968, and served as Tribal Chairwoman from 1971 to 1978. Bennett is also a pioneer of fishing rights advocacy, co-founding the Survival of American Indians Association in 1964, and helping to bring “fish-in” protests to national prominence. Much of Bennett’s work focuses on social welfare issues, mainly fighting for the rights of women, children and families. She began her social service work in the 1950s, with the Seattle’s American Indian Women’s Service League. In 1972, she co-founded the Local Indian Child Welfare Act Committee, where she developed a model for childhood and family services that she used to co-author and secure the national Indian Child Welfare Act of 1978, a Federal law that governs the removal and out-of-home placement of indigenous children. In the 1980s, she co-founded the Rainbow Youth and Family Services in Tacoma, a non-profit which she ran for many years. This photo of Ramona Bennett was taken for a profile of her run by the Seattle Post-Intelligencer in October 1976. At the time, Bennett was chairwoman of the Puyallup Tribal Council.Caption information source: “Ramona Bennett,” The Seattle Civil Rights & Labor History Project, University of Washington, https://depts.washington.edu/civilr/bennett.htm Caption information source: "Ramona Bennett - a Cool, Witty, Charming Leader" by Jack Wilkins, Seattle Post=Intelligencer, October 28, 1976, p. A71 photographic print: b&w; 8 x 10 in

    Portrait of Helen Fiske Hunt Jackson, author of Ramona, [s.d.]

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    Photographic portrait of Helen Fiske Hunt Jackson, author of "Ramona", [s.d.]. Mrs. Jackson is pictured standing, wearing an elaborate dress with a huge bustle, made of what appears to be silk or satin. Her hands are folded across her waist while she looks to the right. She appears to be in her middle-age and wears the large locks of her curly hair pulled back from her face. She can be seen smiling, while a chair supports her dress to the right. Picture file card reads: "An American novelist, poet, and general writer, born at Amherst, mass. October 18, 1831; died at San Francisco, CA, August 12, 1885. She was the daughter of Professor Fiske, of Amherst. He first husband, Capt. E.B. Hunt, died in 1863. In 1870, she published a volume entitled "Verses". Her first prose volume, "Bits of Travel" (1872), was followed by "Bits of Talk About Home Matters" (1873), and "Bits of Travel at Home" (1878). In 1875 she married Mr. W.S. Jackson, of Colorado Springs. Here, she published "A Century of Dishonor", relating to the dealings of the U.S. Government with the Indians. This led to her appointment in 1883 as a special commissioner to examine into the condition and needs of the Mission Indians. After visiting the different tribes, she wrote "Ramona"(1884), a novel relating to the Mission Indians. Mrs. Jackson had previously written two novels in the "no Name" seires: "Mercy Philbric's Chioce" ["Choice"?] (1876) and "Hetty's Strange History"(1877). Besides these works, she published "The Story of Boon", a poem (1879), the training of children(1882), and several books for young people: "Nellie's Silver Mine" (1878), "Mammy Tittleback and her Family" (1881), and "The Hunter Cats of Connorloa" (1884). Since her death have appeared "Glimpses of Three Coasts", "Sonnets and Lyrics", "Zeph", a novel (1886), and "Between Whiles" (1887)"

    Dance to the music of time. by Ramona Koval

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    Coming face to face with thousands of years of Aboriginal culture for the first time, the author found her modern values collapsing all around her

    Cover or title page of "Ramona" by Helen Jackson, ca.1884.

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    Photograph of the cover or title page of "Ramona" by Helen Jackson, ca.1884. The cover reads: "Ramona. A Story. By Helen Jackson (H.H.), Author of 'Verses,' 'Bits of Travel,' 'Bits of Travel at Home,' 'Bits of Talk About Home Matters,' etc. Qui Legit Regit. Boston: Roberts Brothers. 1884"

    Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles Is Suppressed by Tetherin in a Species-Specific Manner

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    Summary: The Ebola virus glycoprotein (EBOV-GP) forms GP-containing microvesicles, so-called virosomes, which are secreted from GP-expressing cells. However, determinants of GP-virosome release and their functionality are poorly understood. We characterized GP-mediated virosome formation and delineated the role of the antiviral factor tetherin (BST2, CD317) in this process. Residues in the EBOV-GP receptor-binding domain (RBD) promote GP-virosome secretion, while tetherin suppresses GP-virosomes by interactions involving the GP-transmembrane domain. Tetherin from multiple species interfered with GP-virosome release, and tetherin from the natural fruit bat reservoir showed the highest inhibitory activity. Moreover, analyses of GP from various ebolavirus strains, including the EBOV responsible for the West African epidemic, revealed the most efficient GP-virosome formation by highly pathogenic ebolaviruses. Finally, EBOV-GP-virosomes were immunomodulatory and acted as decoys for EBOV-neutralizing antibodies. Our results indicate that GP-virosome formation might be a determinant of EBOV immune evasion and pathogenicity, which is suppressed by tetherin. : Nehls et al. demonstrate that the glycoprotein of the highly pathogenic Ebola virus is incorporated into secretory vesicles, called GP-virosomes, to dampen the immune response and capture neutralizing antibodies. The lack of replication competence and the incorporation of antigenically intact GP might qualify GP-virosomes as safe vaccine candidates. Keywords: Ebola virus, glycoprotein, microvesicles, virosome, exosome, tetherin, immune modulation, immune evasion, antiviral immune response, neutralizing antibod

    Movement play as a facilitator of social development of 2-3 year old children

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    Darba autore: Ramona Kravceva. Kvalifikācijas darba “Kustību rotaļa, kā 2-3 gadus vecu bērnu sociālās attīstības sekmētāja” mērķis – izpētīt, kā kustību rotaļas ietekmē bērnu attīstību ikdienā. Cik daudz var atvērties mazākās grupas bērni laika gaitā, izmantojot ikdienā rotaļas, cik liela nozīme kustību rotaļām ir bērnu ikdienā. Darba pirmajā daļā tika analizētas sociālās prasmes, kā tās veidojas un bērnu raksturojums veselumā. Otrajā nodaļā tika analizētas kustību rotaļas, kustību rotaļu procesa organizācija un metodika, to izmantošana veselības un fiziskajā mācību jomā. Trešajā nodaļā tika veikts pētījums, tā metodoloģiskais pamatojums un norises apraksts. Izpētīts tika konkrēta vecuma grupas bērni X pirmsskolas izglītības iestādē, sadarbībā ar grupas pedagogu un tā palīgu. Kvalifikācijas darbs sastāv no 43 lappusēm, tsk., - 6 tabulas, 4 attēli, 2 pielikumi. Izmantoti 33 informācijas avoti.Work author: Ramona Kravceva. The qualification work "Movement play as a facilitator of social development of 2-3 year old children" is to explore how movement play affects children's development in everyday life. How much children in the smaller group can open up over time through daily play, how important movement play is in children's daily lives. The first part of the work analysed social skills, how they are formed and the characteristics of children in the whole. The second chapter analysed movement play, organization and methodology of the movement play process, their use in the field of health and physical learning. In the third chapter, a study, its methodological rationale and description of the course were carried out. Children of a particular age group in X preschool educational institution were studied, in cooperation with the group teacher and its assistant. The qualification work consists of 43 pages, - 6 tables, 4 images, 2 annexes, 33 sources of information have been used

    The Ramona Mission and The Mission Indians

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    Introduction Ramona, the fascinating Indian story by H.H. -- Mrs. H.H. Jackson -- the scenes of which are laid in Southern California, is based upon facts learned and reported by the author on an official inspection of the Mission Indians there in 1883, and it very truthfully and graphically reveals the present condition and hardships, as well as the past sufferings, of those tribes. The story is one of the saddest of many sad records of the race, and is in itself a most moving plea for whatever atonement it is now possible to make to that long-suffering people. But direct appeals for aid in their behalf have also come to The Women\u27s National Indian Association, first, from H. H. herself, and since then from others. In response to these calls a mission is now to be opened by the Association, among the Coahuillas in the village of that name, extending later, it is hoped, to others of the about twenty villages occupied by these Mission Indians. From the official report of Mrs. Jackson, and from later official and other sources, the facts herein presented are taken. But in order to convey an intelligent, general view of the character and circumstances of these Indians, and in response to many requests, these facts are prefaced by a brief historical sketch, and a glance at their present general condition.https://digicom.bpl.lib.me.us/books_pubs/1177/thumbnail.jp

    Student Project: Replication of Author, Author, & Author (201X, JDM, Study X) - Template

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    This project is an independent replication of Author, Author, & Author (201X, study X) conducted as part of the Hagen Cumulative Science Project
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