15,328 research outputs found
MCC-IMS data analysis using automated spectra processing and explorative visualisation methods
No full textBunkowski A. MCC-IMS data analysis using automated spectra processing and explorative visualisation methods. Bielefeld: Bielefeld University; 2012.Ion Mobility Spectrometry (IMS) is a method to characterise chemical substances on the basis of velocity of gas-phase ions in an electrical field. The data resulting from an IMS measurement is a number of spectra sorted by retention time. Each spectrum contains a series of values and each value represents the amount of ionised molecules at one specific drift time. Recent advantages in the field of Ion Mobility Spectrometry lead to an highly increased amount of data per measurement as well as measurements per experiment. Due to the usage of a Multi-capillary Chromatographic Column (MCC) as pre-separation technique the task of analysing and interpreting the resulting data completely changed and now includes a pseudo coloured image in addition to the classic spectra data. Analysing and comparing a high number of these images and their corresponding spectra is almost impossible and extremely time consuming with the methods used so far.
Different methods for spectra processing, data analysis, visualisation and project management were developed and combined in one software called ’IMS Peaklist & Heatmap Explorer’ (IPHEx) to challenge this task. IPHEx is the first software system supporting the analysis, management, and visualisation of large amounts of MCC-IMS measurements in parallel. It is currently used for the investigation of metabolomics experiments with a focus on the analysis of exhaled air, headspace samples of cell and bacteria cultures, as well as general screening of ambient air. While the main methods of IPHEx are designed to process three dimensional data obtained from different MCC-IMS devices,it also handles GC-MS based data for comparison and substance identification as well as several other information obtained from flat and Excel files. It became the standard analysis platform at the Leibniz-Institut für Analytische Wissenschaften ISAS e.V. for MCC-IMS data and showed its potential during the examination of experiments performed in cooperation with the Lungenklinik Hemer - Zentrum für Pneumologie und Thoraxchirurgie, the University Göttingen - Department of Anesthesiology, Emergency and Intensive Care Medicine, the Charité – Universitätsmedizin Berlin and several others. It is also used for experimental purposes at the Korea Institute of Science and Technology, Saarbrücken and the B&S Analytik GmbH, Dortmund.
The application to many different experiments and tasks demonstrates that the requirements have successfully been addressed and the software and therefore the underlying methods and concepts are suited to analyse large amounts of IMS data in an efficient way. With IPHEx, a complete analysis environment exists, which offers a solution for all analysis, management, and visualisation tasks which are necessary to perform a comprehensive investigation of large amounts of MCC-IMS data
Software tool for coupling chromatographic total ion current dependencies of GC/MSD and MCC/IMS
No full textBunkowski A. Software tool for coupling chromatographic total ion current dependencies of GC/MSD and MCC/IMS. Int. J. Ion Mobil. Spectrom. 2010;13(3-4):169-175
Douglas Alexander Stewart, poet, author and playwright
No full textDouglas Alexander Stewart, poet, author and playwrigh
Author inscription in William Hazlitt, essayist and critic; selections from his writings, with a memoir, biographical and critical by Alexander Ireland
No full textAuthor's gift inscription, "To W. C. Hazlitt Esq with kind regards, from Alexr Ireland," with tipped-in review of the book.ASU Library edition has inscription from Ireland to Hazlitt [a child of William Hazlitt?].
Hazlitt , William, 1778-1830.
Ireland, Alexander, 1810-1894
The Author of the Alexander Romance
No full textThis paper, which is based on a portion of the introduction of the author’s edition of Il Romanzo di Alessandro (Mondadori: Fondazione Valla 2007), surveys the generic components of the Alexander Romance in an attempt to arrive at a definition of the work. The argument builds on Merkelbach’s categorisation of elements and uses Fusillo’s insight into the novel as an ‘encyclopaedic genre’ to propose that ‘historical novel’ is not, as Hägg contended, a misnomer for the work. The main components I discuss are: ‘life’; praxeis; chreiai; Cynic elements, including choliambic poetry and utopian perspectives; and the Egyptian aspects of the narrative. A concluding jeu d’esprit offers a characterisation of the putative author, his antecedents and his process of composition.Richard Stoneman was for 25 years editor for classics at Croom Helm and then Routledge. In 1997 he was appointed an Honorary Fellow in the department of classics, University of Exeter. After retiring from publishing in 2006 he has been pursuing his researches on the Alexander legends and teaching a course on the subject at Exeter. His Penguin translation of the Alexander Romance was published in 1991, and a volume of translated Legends of Alexander the Great appeared from Everyman in 1994. Also in 1994 he co-edited Greek Fiction with John Morgan. His edition of the Greek recensions of the Alexander Romance was published (volume I) by the Fondazione Valla in 2007 – volumes II and III will follow over the next few years – and his Alexander the Great: A Life in Legend appeared from Yale University Press in spring 2008. He is the author of a number of other books on Greek history and travel, and is writing a book on oracles
Author Correction: The dengue-specific immune response and antibody identification with machine learning
No full textCorrection to: npj Vaccineshttps://doi.org/10.1038/s41541-023-00788-7, published online 20 January 2024 In this article, the affiliation details for author Alexander Horst were incorrectly given as Alexander Horst1,2 but should have been Alexander Horst1 and other affiliations are renumbered. The original article has been corrected
Alexander Woollcott, author and stage actor
No full textAlexander Woollcott, author and stage actorTo order a reproduction, inquire about permissions, or for information about prices see:
http://www.lib.washington.edu/specialcollections/services/reproduction/reproduction
Please cite the Order NumberScanned at 600ppi with an Epson 20000 flatbed scanner. Image then rotated, cropped, level-adjusted, and sharpened using Photoshop CS3. Converted to a JPEG2000 image upon ingest into CONTENTdm
Lori Alexander: Cook Prize 2025, Silver Medal Acceptance Speech
No full textAuthor Lori Alexander gives an acceptance speech for Cactus Queen: Minerva Hoyt Establishes Joshua Tree National Park (Calkins Creek)https://educate.bankstreet.edu/cook/1017/thumbnail.jp
Catwalks and Collecting: Alexander Fury on Westwood and Galliano
No full textFashion journalist, author, and critic Alexander Fury and MFIT Curator Colleen Hill discussed Fury’s latest book, Vivienne Westwood: The Complete Collections (Yale University Press, 2021). The conversation included an overview of highlights from Fury’s personal collection of fashion, which includes designs by Westwood, John Galliano, Christian Lacroix, among others
„... daß einem leid tut, wie er aufgehört hat, deutsch zu sein“ - Alexander von Humboldt, Preußen und Amerika
No full textAbstractWithin the context of the recent „Prussia Tricentennial 2001“, this paper encourages a different view of Prussia by offering a new look on the writings and activities of one of its most famous citizens, Alexander von Humboldt. Starting with the traditional (and problematic) image of Prussia focussed on the Hohenzollern and, above all, Friedrich II, it highlights the problems between Prussian and German historiography on one side, and the author of „Cosmos“ and his world-wide prestige on the other. Interestingly enough, the tensions or misunderstandings between Alexander and his home country can be dated back to the Humboldt family, i.e. to Wilhelm from Humboldt who noted, in a letter to his wife, how his brother had „stopped to be German“. Alexander von Humboldt's cosmopolitanism and the characteristic development of his scientific conceptions, building a globalized and globalizing praxis based upon a scientific network and continous comparisons in global scale, allow us to discover new dimensions in Humboldtian science and thinking as well as promising perspectives for understanding Alexander von Humboldt's role and significance for transdisciplinary science today -and a different view of Prussia and cultural identity in Europe beyond the well-known stereotypes
- …
