10 research outputs found
ANALISI LINGUISTICA DELL’OPERA LETTERARIA DI VILIAM POKORNI
No full textU radu se razmatra zastupljenost novoselskog čakavskog idioma u djelima Viliama Pokornoga, gradišćanskohrvatskog čakavskog pisca iz Novog Sela u Slovačkoj, kao i utjecaj slovačkoga jezika na jezik tih djela.In the paper the author analyses the presente of the Čakavian idiom of Novo Selo in the works of Viliam Pokorný, the Burgenland Croatian writer from Novo Selo in Slovakia, as well as the influence of Slovak on the language of these works.Nello studio si esamina la presenza dell’idioma ciacavo di Novo Selo nelle opere di Viliam Pokorni, scrittore ciacavo croato di Gradišće orginario di Novo Selo in Slovacchia, come anche l’influenza della lingua slovacca sulla lingua delle stesse opere
POSTMODERN THEATRALITY IN THE WORKS OF VILIAM KLIMÁČEK
No full textViliam Klimáček is nowadays the most known and most successful Slovak playwright. He is also called The Slovak Chekhov. His career began in 1985, when he co-founded an amateur theater company GUnaGU in Bratislava where he started as an actor, musician, director and co-author. As time went by, GUnaGU became professional and Klimáček left his original occupation ? medicine. The poetics of his plays and the artistic style of the company influenced each other through the years and became interdependent. Both show obvious signs of what we can call postmodern aesthetics. In this work we try to analyze the specificity of Klimáček?s and GUnaGU?s style and we try to place it in some larger context. This analysis is not only based on theoretical research but also on a practical experience of directing one of his plays ? Maria Sabina
Projectional editor for domain-specific languages
No full textTitle: Projectional editor for domain-specific languages Author: Ondřej Dvořák Department: Department of Distributed and Dependable Systems Supervisor: RNDr. Michal Malohlava Abstract: Programming is a craft requiring a good tooling. One of tools selected as crucial for software development is an integrated development environment (IDE) that allows to maintain most of the general-purpose languages. Domain-specific languages grow in a popularity last years, thus it is necessary to support them by IDE as well. Not just a textual or graphical form of DSL sources is suitable for their maintenance, so does the combination of them. One of the promising approaches is represented by a novel method called a projectional editing. Its objective is to show different visualization forms of program source code, combine and manipulate with them at one place. The thought is typically realized by a projectional editor. In this thesis we design a projectional editor for domain-specific languages and provide its experimental implementation. It analyzes potential approaches to a projectional editing and designs their suitable realization in Microsoft Visual Studio. It provides a universal implementation of a projectional editor on the top of Visual Studio as well as on the top of a standalone application. Moreover, it supports..
Poems as monuments. Towards outlining a type of occasional lyric in post-WWII literature
No full textOccasional verse is one of the oldest forms of lyric and it can be thought of as a form of materialisation and consolidation of memory. The character of this inevitably fleeting type of poetry that expresses an engagement of its author on a private or public matter much depends on historical and social changes. Occasional verse is inseparably bound
to the time of its composition as it addresses chosen aspects of the era and – especially when it comes to public occasional poems – makes visible the large period narratives. These attributes can also be identified in the Slovak poetry written after 1948 when Czechoslovakia entered the era of state socialism and the poetry in question was part of the system of socialist realism. When observing period’s occasional poetry from
the point of view of memory studies (especially general locations of memory and the theory of memorials), one can note striking similarities (poetological, functional) between a significant proportion of the period poetic production and war memorials built at that time. The article explains these relations as part of the specific construal of the national and socialist narrative in which differences between individual and
collective experience, everyday life and festivities, history and present, memory and history got radically blurred
Interdisciplinary Cooperation in the Virtual Presentation of Industrial Heritage Development
No full textAbstractThe issue of industrial heritage conservation as well as its new use has been worldwide hot topic for a longer period. Industrial heritage provides one of the most important records of urban development and progress of human civilization in the last two centuries. Monumental industrial buildings reflect the extraordinary technical and economic development and the progress in science and technology. Even after the termination of their original function, industrial heritage buildings and equipment's with their architecture are still participating in the atmosphere of each city in a significant way.The electricity industry played a key role in the life of the mankind. Electricity and electrical currents are intangible symbols of the creative use of the natural forces by man, also a real driving force for technological progress and extensive development of human knowledge. The young generation takes it for granted, with no interest in learning about its causal impact and context.A global problem is the decreasing interest of young people in studying natural sciences and engineering, which is a prerequisite for further technological progress and socio-economic development of the life of inhabitants. This lack of interest is justified by the high abstraction and lack of clarity in the scientific and technical fields which are move about from people's everyday lives. Therefore, the current trend is developing an interactive virtual model of presentations of this rich source of knowledge and experiences. Those are able to make technical museums more attractive and allow the inspirational use for a broader audience.The article “Interdisciplinary cooperation in the virtual presentation of industrial heritage development” is aimed to explore opportunities for collaboration between theoretical research, monument preservation, virtual reality and architectural practice. It deals with the identified key factors that conditionally affect the quality and efficiency of architectural design process within the cooperation in the conservation process. As well as it deals with the opportunities of transfer the research results from futuristic disciplines. For this purpose, the paper examines the case study “the reconstruction of old Power plant in city Piestany” and describes one of the possible solutions on the basis of the operational research model so-called “Educational polygon.
Design of Restoration of Regulated Rivers Based on Bioindication
No full textAbstractStreambeds of rivers and brooks should form the dominant features in the urbanized areas. However, the current river regulations were unilaterally focused on flood protection and riverbeds have generally the character of prismatic channel. This solution inhibits the aesthetic function of the watercourses and has the negative impacts on instream biota. Based on the results of the research that was carried out on the mountain streams of Slovakia the authors introduce the implementation of river restorations that maintain the flood protection of the area while retaining the landscaping features of the stream. The paper describes the procedure for restoring the regulated streams based on bioindication and documents the quality of aquatic habitat of regulated and natural streams in particular examples
Hazelcast jet: Low-latency stream processing at the 99.99<sup>th</sup> percentile
No full textJet is an open-source, high-performance, distributed stream processor built at Hazelcast during the last five years. Jet was engineered with millisecond latency on the 99.99th percentile as its primary design goal. Originally Jet’s purpose was to be an execution engine that performs complex business logic on top of streams generated by Hazelcast’s In-memory Data Grid (IMDG): a set of in-memory, partitioned and replicated data structures. With time, Jet evolved into a full-fledged, scale-out stream processor that can handle out-of-order streams and provide exactly-once processing guarantees. Jet’s end-to-end latency lies in the order of milliseconds, and its throughput in the order of millions of events per CPU-core. This paper presents the main design decisions we made in order to maximize the performance per CPU-core, alongside lessons learned, and an empirical performance evaluation.Web Information System
Anticoagulant therapy and outcomes in patients with prior or acute heart failure and acute coronary syndromes: Insights from the APixaban for PRevention of Acute ISchemic Events 2 trial
No full textBackground Clinical outcomes and the effects of oral anticoagulants among patients with acute coronary syndrome (ACS) and either a history of or acute heart failure (HF) are largely unknown. We aimed to assess the relationship between prior HF or acute HF complicating an index ACS event and subsequent clinical outcomes and the efficacy and safety of apixaban compared with placebo in these populations. Methods High-risk patients were randomly assigned post-ACS to apixaban 5.0 mg or placebo twice daily. Median follow-up was 8 (4-12) months. The primary outcome was cardiovascular death, myocardial infarction, or stroke. The main safety outcome was thrombolysis in myocardial infarction major bleeding. Results Heart failure was reported in 2,995 patients (41%), either as prior HF (2,076 [28%]) or acute HF (2,028 [27%]). Patients with HF had a very high baseline risk and were more often managed medically. Heart failure was associated with a higher rate of the primary outcome (prior HF: adjusted hazard ratio [HR] 1.73, 95% CI 1.42-2.10, P < .0001, acute HF: adjusted HR 1.65, 95% CI 1.35-2.01, P < .0001) and cardiovascular death (prior HF: HR 2.54, 95% CI 1.82-3.54, acute HF: adjusted HR 2.52, 95% CI 1.82-3.50). Patients with acute HF also had significantly higher rates of thrombolysis in myocardial infarction major bleeding (prior HF: adjusted HR 1.22, 95% CI 0.65-2.27, P = .54, acute HF: adjusted HR 1.78, 95% CI 1.03-3.08, P = .04). There was no statistical evidence of a differential effect of apixaban on clinical events or bleeding in patients with or without prior HF; however, among patients with acute HF, there were numerically fewer events with apixaban than placebo (14.8 vs 19.3, HR 0.76, 95% CI 0.57-1.01, interaction P = .13), a trend that was not seen in patients with prior HF or no HF. Conclusions In high-risk patients post-ACS, both prior and acute HFs are associated with an increased risk of subsequent clinical events. Apixaban did not significantly reduce clinical events and increased bleeding in patients with and without HF; however, there was a tendency toward fewer clinical events with apixaban in patients with acute HF.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351949500016&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Cardiac & Cardiovascular SystemsSCI(E)[email protected]
Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI) : a phase 3, placebo-controlled, randomised trial
No full textBackground:
Patients with stable coronary artery disease and diabetes with previous percutaneous coronary intervention (PCI), particularly those with previous stenting, are at high risk of ischaemic events. These patients are generally treated with aspirin. In this trial, we aimed to investigate if these patients would benefit from treatment with aspirin plus ticagrelor.
Methods:
The Effect of Ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) was a phase 3 randomised, double-blinded, placebo-controlled trial, done in 1315 sites in 42 countries. Patients were eligible if 50 years or older, with type 2 diabetes, receiving anti-hyperglycaemic drugs for at least 6 months, with stable coronary artery disease, and one of three other mutually non-exclusive criteria: a history of previous PCI or of coronary artery bypass grafting, or documentation of angiographic stenosis of 50% or more in at least one coronary artery. Eligible patients were randomly assigned (1:1) to either ticagrelor or placebo, by use of an interactive voice-response or web-response system. The THEMIS-PCI trial comprised a prespecified subgroup of patients with previous PCI. The primary efficacy outcome was a composite of cardiovascular death, myocardial infarction, or stroke (measured in the intention-to-treat population).
Findings:
Between Feb 17, 2014, and May 24, 2016, 11 154 patients (58% of the overall THEMIS trial) with a history of previous PCI were enrolled in the THEMIS-PCI trial. Median follow-up was 3·3 years (IQR 2·8–3·8). In the previous PCI group, fewer patients receiving ticagrelor had a primary efficacy outcome event than in the placebo group (404 [7·3%] of 5558 vs 480 [8·6%] of 5596; HR 0·85 [95% CI 0·74–0·97], p=0·013). The same effect was not observed in patients without PCI (p=0·76, p interaction=0·16). The proportion of patients with cardiovascular death was similar in both treatment groups (174 [3·1%] with ticagrelor vs 183 (3·3%) with placebo; HR 0·96 [95% CI 0·78–1·18], p=0·68), as well as all-cause death (282 [5·1%] vs 323 [5·8%]; 0·88 [0·75–1·03], p=0·11). TIMI major bleeding occurred in 111 (2·0%) of 5536 patients receiving ticagrelor and 62 (1·1%) of 5564 patients receiving placebo (HR 2·03 [95% CI 1·48–2·76], p<0·0001), and fatal bleeding in 6 (0·1%) of 5536 patients with ticagrelor and 6 (0·1%) of 5564 with placebo (1·13 [0·36–3·50], p=0·83). Intracranial haemorrhage occurred in 33 (0·6%) and 31 (0·6%) patients (1·21 [0·74–1·97], p=0·45). Ticagrelor improved net clinical benefit: 519/5558 (9·3%) versus 617/5596 (11·0%), HR=0·85, 95% CI 0·75–0·95, p=0·005, in contrast to patients without PCI where it did not, p interaction=0·012. Benefit was present irrespective of time from most recent PCI.
Interpretation:
In patients with diabetes, stable coronary artery disease, and previous PCI, ticagrelor added to aspirin reduced cardiovascular death, myocardial infarction, and stroke, although with increased major bleeding. In that large, easily identified population, ticagrelor provided a favourable net clinical benefit (more than in patients without history of PCI). This effect shows that long-term therapy with ticagrelor in addition to aspirin should be considered in patients with diabetes and a history of PCI who have tolerated antiplatelet therapy, have high ischaemic risk, and low bleeding risk
