1,720,960 research outputs found
Adipose tissue composition and distribution differences in predicting metabolic disorders in obese patients.
No full textThe prevalence of obesity is increasing worldwide, and more than 20% of all human population are obese. It has been shown that there exists a subset of the obese population without any metabolic abnormalities. This phenotype of obesity is termed as metabolically healthy obesity. It was determined that metabolically healthy obese patients have a distinct fat distribution pattern, a favorable inflammatory profle as well as different adipose tissue metabolism and composition. Despite the increased interest in the metabolically normal obesity, there are no unique criteria to define metabolic health. A better understanding of the underlying causes of metabolic health would help to distinguish the obesity phenotypes, aid in the development of new preventive strategies for those who are at a greater risk of developing metabolic abnormalities and prevent any excessive dieting, pharmacological and surgical treatments in healthy obese individuals. This study used anthropometric, ultrasonographic and 1H-MRS tools to determine whether superfcial and deep subcutaneous, preperitoneal and visceral adipose tissue depots differed in their distribution and fatty acid composition in obese patients with and without metabolic syndrome. Our research proved that visceral adipose tissue thickness measured using ultrasonography and adipose tissue composition has a strong correlation with the determinants of metabolic health. It was found that adiponectin concentration, visceral adipose tissue thickness measured using ultrasonography and fatty acids in subcutaneous adipose tissue are independent prognostic factors in metabolic syndrome determination in obese patients
Riebalinio audinio pasiskirstymo ir riebalų sudėties skirtumai tarp metabolinių sutrikimų turinčių ir neturinčių nutukusių pacientų. Disertacijos santrauka.
No full textThe prevalence of obesity is increasing worldwide, and more than 20% of all human population are obese. It has been shown that there exists a subset of the obese population without any metabolic abnormalities. This phenotype of obesity is termed as metabolically healthy obesity. It was determined that metabolically healthy obese patients have a distinct fat distribution pattern, a favorable inflammatory profle as well as different adipose tissue metabolism and composition. Despite the increased interest in the metabolically normal obesity, there are no unique criteria to define metabolic health. A better understanding of the underlying causes of metabolic health would help to distinguish the obesity phenotypes, aid in the development of new preventive strategies for those who are at a greater risk of developing metabolic abnormalities and prevent any excessive dieting, pharmacological and surgical treatments in healthy obese individuals. This study used anthropometric, ultrasonographic and 1H-MRS tools to determine whether superfcial and deep subcutaneous, preperitoneal and visceral adipose tissue depots differed in their distribution and fatty acid composition in obese patients with and without metabolic syndrome. Our research proved that visceral adipose tissue thickness measured using ultrasonography and adipose tissue composition has a strong correlation with the determinants of metabolic health. It was found that adiponectin concentration, visceral adipose tissue thickness measured using ultrasonography and fatty acids in subcutaneous adipose tissue are independent prognostic factors in metabolic syndrome determination in obese patients
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Riebalinio audinio pasiskirstymo ultragarsinio tyrimo metodikos: sisteminė literatūros apžvalga
Get PDF[straipsnis ir santrauka lietuvių kalba; santrauka anglų kalba]
Įvadas / tikslas
Apžvelgti poodinio ir visceralinio riebalinio audinio matavimams naudojamas ultragarsines metodikas ir nustatyti metodiką, tinkamiausią nutukusiems ligoniams.
Metodai
Publikacijų paieška atlikta naudojantis „PubMed“, „Current Contents“ ir „Cochrane Library“ duomenų bazėmis. Į sisteminę apžvalgą įtrauktos visos iki 2017 m. gruodžio 1 d. paskelbtos publikacijos, kuriose ultragarsiniai riebalinio audinio matavimai lyginti su kompiuterinės tomografijos ar magnetinio rezonanso tyrimų duomenimis.
Rezultatai
Į sisteminę apžvalgą įtraukta 17 studijų, kuriose nagrinėjami ultragarsinių riebalinio audinio matavimų duomenys. Šiose studijose ištirti 1 085 ligoniai. Studijose, lyginančiose įvairių autorių ultragarsinio tyrimo ir kompiuterinės tomografijos ar magnetinio rezonanso tyrimo metu išmatuoto riebalinio audinio pasiskirstymą, nustatytas visceralinio riebalinio audinio rodiklių koreliacijos koeficientas siekė nuo 0,63 iki 0,94, poodinio riebalinio audinio rodiklių – nuo 0,33 iki 0,96. Šešiose studijose išskirtos nutukusių ar morbidiniu nutukimu sergančių asmenų grupės (KMI ≥30 kg/m2). Tiriant nutukusius asmenis, geriausių rezultatų pasiekta naudojant modifikuotą R. P. Stolk’o metodiką. Visceralinio riebalinio audinio rodiklių koreliacijos koeficientas tarp kompiuterinės tomografijos ir ultragarso siekė 0,823, poodinio riebalinio audinio – 0,745, o, tiriant morbidiniu nutukimu sergančius ligonius, tyrimų patikimumo rodikliai siekė 0,94.
Išvados
Ultragarsinis tyrimas yra pigus, neinvazyvus, prieinamas ir kartotinis tyrimo metodas. Šį metodą taikant riebalinio audinio pasiskirstymui matuoti, galima atlikti didelės apimties populiacijos tyrimus. Nutukimu sergančių ligonių riebalinio audinio pasiskirstymui matuoti rekomenduojama ultragarsinė, modifikuota R. P. Stolk’o metodika
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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