312 research outputs found
Data for Contrasting action and posture coding with hierarchical deep neural network models of proprioception
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Contrasting action and posture coding with hierarchical deep neural network models of proprioception, eLife 2023
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Authors: Kai J Sandbrink, Pranav Mamidanna, Claudio Michaelis, Matthias Bethge, Mackenzie W Mathis and Alexander Mathis
Affiliation: Brain Mind Institute, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Switzerland, The Rowland Institute at Harvard, Harvard University, United States; Tübingen AI Center, Eberhard Karls Universität Tübingen & Institute for Theoretical Physics, Germany
Date of upload: December, 2024
Earlier the data was available via dropbox (see github).
Link to the eLife article:
https://elifesciences.org/articles/81499
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Here we provide the data and code for this project:
We share the proprioceptive character recognition dataset (contained in 'pcr_data.zip') it has approximately ~29GB when uncompressed.
We share the weights of all the trained networks (contained in 'network-weights.zip'): about ~3.5GB
The compressed code is also available here ('DeepDrawCode.zip').
The activations are shared in a separate Zenodo project (due to the size). Check out the repository below to find the link.
The up to date code is at: https://github.com/amathislab/DeepDraw
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The datasets, weights, activations and predictions are released with Creative Commons Attribution 4.0 license.
If you find this useful, please cite:
@article{sandbrink2023contrasting, title={Contrasting action and posture coding with hierarchical deep neural network models of proprioception}, author={Sandbrink, Kai J and Mamidanna, Pranav and Michaelis, Claudio and Bethge, Matthias and Mathis, Mackenzie Weygandt and Mathis, Alexander}, journal={Elife}, volume={12}, pages={e81499}, year={2023}, publisher={eLife Sciences Publications Limited}}UPAMATHISUPMWMATHI
First Dallas High School class at Old Bryan High 50 years ago. (Picture taken 1936, with individuals identified.)
No full textImage of the first Dallas High School class approximately 50 years later.Title from finding aid. Recto: [typewritten] No. 528. First Dallas High Class at Old Bryan High 50 Years Ago. First Row: Edward A. Belsterling, N. E. Mittenthal, John W. Philp, Rev. Richard Morgan, Dr. John O. McReynolds only living man teacher of 1886, Will S. Mosher. 2row: Ike Israel, W. P. Anderson, Dr. Frank J. Hall, Mack Ernest, J. J. Carnes, Richard E. Bramlett, Arthur S. Mathis. 6 row: Arthur D. Tompkins, Albert H. Estes, Clark Burr. Dr. Bush Jones, Edgar L. Flippen. 3row: Joe B. Cave, Geo. W. Loudermilk, Terry J. Moseley, Waid H. Waggener, M. L. Crawford, 4 row: Pierre L. Russell, Will L. Peacock, John M. Spellman, W. Sherwood Bramlett, L. L. Bristol. 5rwo [sic]
Sepedonea giovana Marinoni & Mathis, 2006, sp. nov.
No full text<i>Sepedonea giovana</i>, sp. nov. (Figs. 1 –11; 27; 41) <p> <i>Sepedonea guianica</i> of authors, not Steyskal [misidentification]. Knutson et al. 1976: 11 [Neotropical catalog; partim]. Knutson & Valley 1978: 198 [review; partim]. Freidberg <i>et al</i>. 1991: 16 [revision; partim].</p> <p> <i>Sepedonea vau.</i> Mello and Bredt 1978: 1459 [nomen nudum; phenology].</p> <p> <b>Diagnosis.</b> This species is distinguished from congeners (described in Freidberg <i>et al.</i>, 1991) especially <i>S. guianica,</i> by the following combination of characters: Mesonotum grayish black; setulae near posterior thoracic spiracle moderately numerous, weak but well developed. Wing (Fig. 5) infuscate, clouded. Midfemur bearing 3–5 spine­like setae posteroventrally; hindfemur with more or less discrete, usually dark, preapical lateral mark.</p> <p> <b>Description.</b> Adult. <i>Head:</i> Ocellar seta absent; postocellar seta absent. Fronto­orbital spot absent; orbito­antennal spot absent; face with a large brown spot at ventral corner.</p> <p> <i>Thorax:</i> Mesonotum grayish black; postpronotum brownish; setulae near posterior spiracle moderately strong and dense; setation near posterior spiracle weakly developed; setae on katatergal callus absent. Wing: Length 5.0–6.0 mm; brownish, usually clouded anteroapically and over crossveins r­m and dm­cu. Legs: Forefemur bearing at least 1 well­developed seta; midfemur usually bearing 3–6 spine­like setae posteroventrally, not extended beyond half distance to base, lacking setae along anterior surface; hindcoxa bearing short setulae posteriorly, mostly restricted to medial portion; hindfemur claviform, usually with dark, preapical marks, height/width ratio 4.5–5.0; hindtibia with a spinelike projection but lacking a distinctive seta at ventroapical margin.</p> <p> <i>Abdomen:</i> Male terminalia (Figs. 6–10): Posterior margin of 4th sternite deeply emarginate, with 2 lateral processes (Fig. 7); anterior plate of 5th sternite not reduced, with wide, indented flange at posteromedial margin folded ventrally (Fig. 6), posterior portion with a pair of moderately­sized processes; distiphallus (Fig. 8) sinuous, with posteroventral angle covered by large flat, setulose epiphallus; anterior surstylus small, indistinct; posterior surstyli completely fused to form a medial structure, this structure without a medial lobe; posterior surstylus with lateral lobe moderately strongly curved anteriorly (Fig. 9); epiphallus large; distiphallus absent. Female synsternite (Figs. 11; 27): Posterior margin in ventral view with ventral surface more or less straight, and with posterior ridge distinctly projected, rounded (Fig. 11); spermathecal duct at junction with spermatheca divided in 2 portions, portion closest to spermatheca wide (Fig. 27).</p> <p> <b>FIGURES 6–11.</b> <i>Sepedonea giovana</i> <b>sp. n.</b> 6. male 5th sternite; 7. male 4th sternite; 8. distiphallus lateral view; 9. posterior surstyli, posterior view; 10. posterior surstyli, lateral view; 11. female synsternite, ventral view.</p> <p> <b>Type specimens.</b> The holotype male is labeled “ BRAZIL: Minas Gerais: 17 km N of Belo Horizonte [43°56’W. 19°45’S] C. O. Berg 18–23 July 1964 / HOLOTYPE ɗ <i>Sepedonea giovana</i> Marinoni & Mathis [red].” The holotype is directly pinned, is in excellent condition, and is deposited in the USNM. Twenty­five male paratypes bear the same locality label as the holotype (DZUP, USNM). Other paratypes are as follows: BRAZIL. <i>Minas Gerais:</i> Belo Horizonte (43°56’W. 19°55’S), 18–23 Jul 1964, C. O. Berg (3ɗ, 3Ψ; USNM). <i>Paraná</i>: Curitiba (61 km S), Rio Varzea (49°15’W. 25°58’S), 16 May 1967, J. Abercrombie, C. O. Berg (5ɗ, 2Ψ; USNM); Morretes (6 km SE; 48°46.7’W. 25°30.3’S), 4–17 May 1967, J. Abercrombie, C. O. Berg (1Ψ; USNM); Praia do Leste (48°28’W. 25°41.5’S), 4 May 1967, J. Abercrombie, C. O. Berg (10ɗ, 11Ψ; DZUP, USNM); Rio Iguassu at Araucaria (51°12’W. 30°48’S), 1 May 1967, J. Abercrombie, C. O. Berg (1ɗ; USNM). <i>Rio Grande do Sul:</i> Porto Alegre (87 km S; 51°12’W. 30°48’S), 10 May 1967, J. Abercrombie, C. O. Berg (1Ψ; USNM). <i>Santa Catarina:</i> Lajes (5 km W; 50°21.7’W. 27°48’S), 6 May 1967, J. Abercrombie, C. O. Berg (1ɗ; USNM); Lajes (30 km S; 50°19’W. 28°04.2’S), 12 May 1967, J. Abercrombie, C. O. Berg (1Ψ; USNM). <i>São Paulo</i>: São José do Rio Preto (48°23’W. 20°48.1’S), 27 Jul 1966, N. Papavero (1ɗ; USNM).</p> <p> <b>Type locality.</b> Brazil. Minas Gerais: Belo Horizonte (17 km N; 43°56’W. 19°45’S).</p> <p> <b>Other specimens examined.</b> ARGENTINA. <i>Tucumán:</i> Monteros (65°30’W. 27°12’S), 7 Feb 1967, C. O. Berg, J. Abercrombie (1ɗ; USNM).</p> <p> BRAZIL. <i>Minas Gerais</i>: Jockey Club, 23 Aug–15 Sep 1966, C. O. Berg (12ɗ, 3Ψ; USNM).</p> <p> <b>Locality records from Mello & Bredt (1978).</b> BRAZIL. <i>Distrito Federal:</i> Núcleo Bandeirantes (47°58’W. 15°52’S), 11 Nov 1974, D. A. Mello, A. Bredt; Riberão Extrema, DF 21, 6 Feb 1974, D. A. Mello, A. Bredt. <i>Minas Gerais:</i> Hipódromo Serra Verde, Santa Luzia (43°20.6’W. 21°47.3’S), 24 Aug 1974, D. A. Mello, A. Bredt. <i>Goiás:</i> Rio Preto, Formosa (47°20’W. 15°32’S), 19 Jun 1974, Jan–May, Jul–Oct, Dec 1975, 1976, D. A. Mello, A. Bredt.</p> <p> <b>Distribution (Fig. 41).</b> Neotropical: Argentina (Tucumán) and Brazil (Goiás, Distrito Federal, Espirito Santo, Minas Gerais, Paraíba, Paraná, São Paulo).</p> <p> <b>Etymology.</b> The species epithet, <i>giovana,</i> is a noun in apposition and is named after the delightful daughter of the first author and her husband, Sionei Ricardo Bonatto, whose support is also appreciated.</p> <p> <b>Remarks.</b> Externally, the species of <i>Sepedonea</i> are difficult to distinguish and reference to structures of the male terminalia is usually needed to determine species accurately.</p> <p> The distribution map includes a few localities that we extracted from Mello & Bredt (1978), as noted above. We did not include localities they listed that may apply to another species, such as <i>S. guianica,</i> as we did not have access to these specimens to verify determinations of species.</p>Published as part of <i>Marinoni, Luciane & Mathis, Wayne N., 2006, A cladistic analysis of the Neotropical genus Sepedonea Steyskal (Diptera: Sciomyzidae), pp. 37-52 in Zootaxa 1236</i> on pages 40-43, DOI: <a href="http://zenodo.org/record/172789">10.5281/zenodo.172789</a>
Camp Floyd in retrospect
No full textthesisDuring the period of United States History typified by the westward movement, military posts were established along the main routes of travel for the principal purpose of providing protection to those hardy souls who looked to the setting sun for a better way of life. There was at least one exception to this practice, however, and it is the topic of this thesis. The author has an abiding interest in military movements in the West and a desire to learn more of the contribution made to America by dusty cavalrymen and footsore infantry men. This study of Camp Floyd, Utah Territory, grew out of this interest, which bordered at times on obsession. Though Camp Floyd was typical of western outposts in many respects, it was still unique in the purpose of its establishment- to quell the reported rebellion of subjects of the United States. An attempt has been made in this work to capture the excitement and romance experienced by the frontier soldiers stationed at Camp Floyd, as well as to discuss their several contributions to the development of the West. Appreciation is expressed to the many people and institutions who aided the author in preparing this work; to Dr. Leland H. Creer, Head of the Department of History at the University of Utah, for his guidance and encouragement in supervising this thesis, to Dr. David E. Miller, Professor of History at the University, for his detailed reading of this work and for his helpful suggestions on style and phraseology, to the University of Utah Library, Utah State Historical Society, the Bancroft Library, and the L.D.S. Church Historian*s Office for making available the primary material used in this thesis, and to the author\u27s grandfather, Henry George Mathis, a pioneer of Utah, who was directly influenced by the topic of this paper. Especial appreciation is due the author*s wife, Sara-Beth, for her untiring efforts in typing this thesis and for the patience, understanding, and encouragement she has expressed to him in the preparation of this work
Uintah Chapter of FFA 1994
No full textMembers of the Future Farmers of America (FFA) Uintah Chapter are from left, back row, Melissa Dimick, Morgan McCoy, Fred Reynolds, Adam Harrison, Kimberly Kicenski, Chris Davidson, C. Kunz, Ryan Brisk, K. Johnson, Ryan Kunkle, Jeremy Kempton, Robbie McClure, Joshua Smuin, Justin Nash, Brock Kidd, Sean Latham, Elijah Jackson and Phillip Davis. Center row, R. Snow, Melissa Smith, Lindsey Reynolds, Raleen White, Cory Hawkins, Jeremy Harrison, Shawn Dansie, Nikki Hascall, Sabrina Chalk, Jessica Caldwell and Ginger Stringham. Officers at Desk, Dan Harris, advisor; Jared Davis, Bryan Bell, Jennifer Gilroy, Milton Buker, president; Heath Harris and Erika Bloom. Front, Brett Bell, Tony Batty, M. Mathis and Bridger Murray
ACADEMIC PRODUCTIVITY AFTER COLON AND RECTAL SURGERY FELLOWSHIP
No full textPurpose/Background: Early career publication productivity among academic surgeons after Colon and Rectal Surgery (CRS) Fellowship has not been studied. Hypothesis/Aim: We aimed to describe predictive factors of academic surgeons’ publication productivity using pre-CRS fellowship characteristics. Methods/Interventions: Candidates included those applying for CRS fellowship at Mayo Clinic between 2015 and 2018 and appointed in an academic position post-fellowship. Academic position was defined as Instructor, Assistant Professor, Associate Professor, or Professor. It was assessed through a cross-checking of information on public online sources (American College of Surgeons, American Society of Colon and Rectal Surgeons, university website, and social media). Academic position and publications were blindly assessed by three authors (G.C, S.A., S.B.) in July 2021, any incongruity was further resolved. The number of publications post-fellowship and authorship positions was retrieved from PubMed, with a median follow-up of 2.5 years [range: 1-4 years]. Academics top quartile (Q1) was defined according to a composite productivity outcome of publications/year ratio as first, last and any-position author. Data were compared between Q1 and the less productive quartiles (Q2-4). Pre-fellowship data were retrieved from the Electronic Residency Application Service (ERAS®) application. Results/Outcome(s): Among 130 defined academic surgeons, first author, last author, and any position publications were less than one publication/year ratio in 80%, 86%, and 47%, respectively. First author publications were one, two, or ≥three publications/year ratio in 16%, 4%, and 2% of the academics, while last author publications in 9%, 3%, and 3%. Overall, the number of publications as any author position was one in 21%, two in 13%, three to five in 11%, and >five publications/year ratio in 10% of the academics. Academics in the top quartile (Q1) more frequently attended a top-20 medical school, top-20 Surgery Residency Program, and completed a Research Fellowship. Prior to fellowship, Q1 academics had more publications as 1st author and had more presentations. Understandably, these individuals frequently received research awards and had earned advanced degrees (Master/PhD) (Table 1). Limitations: Its retrospective nature and follow-up duration limited our study. Conclusions/Discussion: Among early-career academics, half coauthored less than one article/year after CRS fellowship, and more than 80% authored less than one article/year as first or last author. Conversely, academics with the highest publication productivity during their early career demonstrated high pre-fellowship research and publication performances
Transcriptional And Post-Transcriptional Regulation Of NRF2 In The Heart By The Deubiquitinase CYLD
No full textThe cylindromatosis (CYLD) is a K63-linked deubiquitinase (DUB) that has been linked to the regulation of multiple physiological or pathological processes, such as neural development, inflammation and fibrosis. However, a novel paradigm for CYLD has been recently postulated; namely that of CYLD as a mediator of cardiac disease. Nuclear factor, erythroid-2 related factor 2 (Nrf2), a master antioxidant transcription factor, has been shown to suppress cardiac pathological remodeling and dysfunction via downregulation of reactive oxygen species formation (ROS). It is normally regulated by Kelch-like ECH associated protein 1 (Keap1). However, the regulatory link between CYLD and Nrf2 in the diseased heart has heretofore been unclear. In this study, a potential role of CYLD in the control of Nrf2 signaling in the heart is proposed. I found that, in a mouse model of pressure overload-induced cardiac remodeling and dysfunction via transverse aortic constriction (TAC), knockout of CYLD attenuates cardiac oxidative stress, pathological remodeling and dysfunction associated with upregulation of Nrf2- mediated antioxidant signaling. At the molecular level, CYLD inactivates MAPK/AP-1 and c-Myc pathways which are required to activate Nrf2-operated antioxidant defense in cardiomyocytes. Moreover, CYLD is capable of suppressing autophagy-dependent posttranscriptional upregulation of Nrf2 expression via activation of mammalian target of rapamycin complex 1 (mTORC1), contributing to cardiomyocyte necrosis.
Taken together, these results reveal that CYLD functions as a mediator of cardiac pathological remodeling and dysfunction via facilitating cardiomyocyte death by suppressing Nrf2-driven antioxidant defense. CYLD may serve as an important target for future therapies
Detailed optical and near-infrared polarimetry, spectroscopy and broad-band photometry of the afterglow of GRB 091018 : polarization evolution
No full textFollow-up observations of large numbers of gamma-ray burst (GRB) afterglows, facilitated by the Swift satellite, have produced a large sample of spectral energy distributions and light curves, from which their basic micro- and macro-physical parameters can in principle be derived. However, a number of phenomena have been observed that defy explanation by simple versions of the standard fireball model, leading to a variety of new models. Polarimetry can be a major independent diagnostic of afterglow physics, probing the magnetic field properties and internal structure of the GRB jets. In this paper we present the first high-quality multi-night polarimetric light curve of a Swift GRB afterglow, aimed at providing a well-calibrated data set of a typical afterglow to serve as a benchmark system for modelling afterglow polarization behaviour. In particular, our data set of the afterglow of GRB 091018 (at redshift z = 0.971) comprises optical linear polarimetry (R band, 0.13-2.3d after burst); circular polarimetry (R band) and near-infrared linear polarimetry (Ks band). We add to that high-quality optical and near-infrared broad-band light curves and spectral energy distributions as well as afterglow spectroscopy. The linear polarization varies between 0 and 3per cent, with both long and short time-scale variability visible. We find an achromatic break in the afterglow light curve, which corresponds to features in the polarimetric curve. We find that the data can be reproduced by jet break models only if an additional polarized component of unknown nature is present in the polarimetric curve. We probe the ordered magnetic field component in the afterglow through our deep circular polarimetry, finding P circ < 0.15per cent (2σ), the deepest limit yet for a GRB afterglow, suggesting ordered fields are weak, if at all present. Our simultaneous R- and Ks-band polarimetry shows that dust-induced polarization in the host galaxy is likely negligible
Models of diffuse Hα in the interstellar medium : the relative contributions from in situ ionization and dust scattering
No full textJB acknowledges the support of an STFC studentship. LMH acknowledges support from the US National Science Foundation through award AST-1108911.Using three-dimensional Monte Carlo radiation transfer models of photoionization and dust scattering, we explore different components of the widespread diffuse Hα emission observed in the interstellar medium of the Milky Way and other galaxies. We investigate the relative contributions of Hα from recombination emission in ionized gas and Hα that originates in HII regions near the Galactic mid-plane and scatters off high-altitude dust in the diffuse interstellar medium. For the radiation transfer simulations, we consider two geometries for the interstellar medium: a three-dimensional fractal geometry that reproduces the average density structure inferred for hydrogen in the Milky Way, and a density structure from a magnetohydrodynamic simulation of a supernova-driven turbulent interstellar medium. Although some sight lines that are close to HII regions can be dominated by scattered light, overall we find that less than ~20 per cent of the total Hα intensity in our simulations can be attributed to dust scattering. Our findings on the relative contribution of scattered Hα are consistent with previous observational and theoretical analyses. We also investigate the relative contributions of dust scattering and in situ ionization of high-density dust clouds in the diffuse gas. Dust scattering in these partially ionized clouds contribute ~40 per cent to the total intensity of Hα.Peer reviewe
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