951 research outputs found
The blind spots of secularization
No full textAccording to several international surveys Spain is among the western countries with the most negative views of Jews. While quantitative data on the topic accumulates, there is a significant lack of interpretative approaches that might explain the particular Spanish case. This paper presents the background, methodology and major results of a discussion group-based study on antisemitism, which was conducted in Spain in the autumn of 2009. The study identifies and locates in different socio-economic and ideological milieus the range of stereotypical discourses on Jews, Judaism and the Arab–Israeli conflict in Spain. Analysis of the group meetings shows that, despite growing secularization in Spanish society, the central explanatory variable for persisting and resurging antisemitism in this country is still religion in a broad cultural sense.N
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Rectifying the Misconceptions about Current Best Management of Asymptomatic Carotid Stenosis is Not about Revising History
No full textMétricas de autor Alejandro Gómez Jaramillo
No full textInforme de las métricas de autor del Dr. Alejandro Gómez Jaramillo de las publicaciones indexadas en Google Académico cuyo objetivo es entregar un insumo para el fortalecimiento de las capacidades y potencialidades de los autores de la Universidad Santo Tomás en el posicionamiento y visibilidad de sus publicacionesReport of the author metrics Alejandro Gómez Jaramillo of the publications indexed in Google Scholar whose objective is to provide an input for the strengthening of the capacities and potentialities of the authors of the Santo Tomás University in the positioning and visibility of their publications.http://unidadinvestigacion.usta.edu.c
. 650 Año 13 (2014) noviembre. El Tlacuache
No full text- Celebrando 15 años de ser Patrimonio de la Humanidad por Arqlgo. José Cuauhtli A. Medina Romero y LDG. Joanna Morayta Konieczna. - Humboldt y Xochicalco, apuntes sobre su relación por Eduardo Corona-M. - Monumento de Xochicalco por Alejandro de Humboldt. - Reconocimiento al Mérito Estatal de Investigación 2014 por Equipo Editorial del Suplemento Cultural “El Tlacuache”
El Tlacuache Núm. 379 (2009). 379 Año 9 (2009) agosto. El Tlacuache
No full textEl Jardín Etnobotánico: revalorando tradiciones por Leonardo Alejandro Beltrán Rodríguez, L. Gabriela Avalos Becerril, Feliciano García Lara. -Cultura para niños en verano. - Mario Romero: un héroe municipal encarcelado por Víctor M. Toledo
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Additional Opportunity to Rectify Misconceptions Regarding Current Best Management of Asymptomatic Carotid Stenosis
No full textOptimizing the Definitions of Stroke, Transient Ischemic Attack, and Infarction for Research and Application in Clinical Practice
No full textBackground and purposeUntil now, stroke and transient ischemic attack (TIA) have been clinically based terms which describe the presence and duration of characteristic neurological deficits attributable to intrinsic disorders of particular arteries supplying the brain, retina, or (sometimes) the spinal cord. Further, infarction has been pathologically defined as death of neural tissue due to reduced blood supply. Recently, it has been proposed we shift to definitions of stroke and TIA determined by neuroimaging results alone and that neuroimaging findings be equated with infarction.MethodsWe examined the scientific validity and clinical implications of these proposals using the existing published literature and our own experience in research and clinical practice.ResultsWe found that the proposals to change to imaging-dominant definitions, as published, are ambiguous and inconsistent. Therefore, they cannot provide the standardization required in research or its application in clinical practice. Further, we found that the proposals are scientifically incorrect because neuroimaging findings do not always correlate with the clinical status or the presence of infarction. In addition, we found that attempts to use the proposals are disrupting research, are otherwise clinically unhelpful and do not solve the problems they were proposed to solve.ConclusionWe advise that the proposals must not be accepted. In particular, we explain why the clinical focus of the definitions of stroke and TIA should be retained with continued sub-classification of these syndromes depending neuroimaging results (with or without other information) and that infarction should remain a pathological term. We outline ways the established clinically based definitions of stroke and TIA, and use of them, may be improved to encourage better patient outcomes in the modern era
CRIMEN Y CASTIGO. A PROPÓSITO DE PENA CAPITAL DE ALEJANDRO TOMASINI
No full textThis paper deals with the topic of death penalty and the right to life. In the first section a revision of the historical paradigmatic positions about this topic is made. In the second section, Alejandro Tomasini Bassols´argumentation in favour of maximun penalty is analized in detail. This essay tends to refute the philosophical defence of death penalty done by the author from his own suppositions.Este trabajo versa principalmente sobre el tema de la pena de muerte y del derecho a la vida. En la primera sección se pasa revista a las posiciones históricamente paradigmáticas respecto de la cuestión. En la segunda, se analiza puntualmente la argumentación que Alejandro Tomasini Bassols brinda a favor de la pena máxima. La presente nota crítica aspira a refutar la defensa filosófica que el autor hace de la pena capital desde sus propios supuestos
Genomic characterization of schizophrenia candidate gene regions
No full textSchizophrenia (SZ) is a severe mental disorder with a complex genetic etiology and a lifetime prevalence of ~0.55-1%. In this study, we extracted and analyzed data from 47 independent genomewide scans for linkage to SZ. The genome was partitioned into 22 schizophrenia candidate gene regions (SCRs) by applying three methods: single significant approach, disjoint approach, and smoothing method. For the single significant hit approach, an SCR was defined by the presence of a significant hit by extending 10 cM upstream and downstream of that hit. For the disjoint approach, we identified criteria-events based on clustering of hits within small regions by using a sliding window approach. For the smoothing method, we imputed a randomized range of p-values (0.001697≤p<1) for the genome scans without a suggestive or significant result at each 0.1 cM interval. We combined these p-values with the genome scan results using three methods: geometric mean method, Fisher’s method, and Stouffer’s method. We characterized each SCR by identifying the genes and genomic elements such as structural variations, regulatory elements, and functional noncoding RNAs. We also categorized the genes within SCRs. The total coverage of SCRs is 880 cM (739 Mb) with SCR sizes ranging from 18 cM to 87 cM. SCRs with multiple peaks were divided into smaller subregions. We developed a ranking system to identify and prioritize SZ candidate genes by assigning weights to each of the following criteria: (a) relative significance of a peak within an SCR, (b) annotated in SZ association studies and microarray analyses, and meta-analyses, (c) associated with phenotypes or diseases, and (d) located within or near other genetic elements. We identified functions/diseases and pathways that were most significantly associated with genes that had at least the same score or better than the top 10% of candidate genes after prioritization by utilizing the Ingenuity® Pathways Analysis (IPA). We generated an interactome for SZ based on the SZ candidate genes. We created a website (http://compgen.rutgers.edu/schiz) to disseminate information about our SCRs. Our procedure, which provides a novel approach to identify and prioritize candidate gene regions and genomic elements, is applicable to other complex diseases.Ph. D.Includes bibliographical referencesby Alejandro Q. Nato, Jr
Misconceptions regarding the adequacy of best medical intervention alone for asymptomatic carotid stenosis
No full textBACKGROUND: Medical intervention (risk factor identification, lifestyle coaching, and medication) for stroke prevention has improved significantly. It is likely that no more than 5.5% of persons with advanced asymptomatic carotid stenosis (ACS) will now benefit from a carotid procedure during their lifetime. However, some question the adequacy of medical intervention alone for such persons and propose using markers of high stroke risk to intervene with carotid endarterectomy (CEA) and/or carotid angioplasty/stenting (CAS). Our aim was to examine the scientific validity and implications of this proposal. METHODS: We reviewed the evidence for using medical intervention alone or with additional CEA or CAS in persons with ACS. We also reviewed the evidence regarding the validity of using commonly cited makers of high stroke risk to select such persons for CEA or CAS, including markers proposed by the European Society for Vascular Surgery in 2017. RESULTS: Randomized trials of medical intervention alone versus additional CEA showed a definite statistically significant CEA stroke prevention benefit only for selected average surgical risk men aged less than 75 to 80 years with 60% or greater stenosis using the North American Symptomatic Carotid Endarterectomy Trial criteria. However, the most recent measurements of stroke rate with medical intervention alone are overall lower than for those who had CEA in these randomized trials. Randomized trials of CEA versus CAS in persons with ACS were underpowered. However, the trend was for higher stroke and death rates with CAS. There are no randomized trial results related to comparing current optimal medical intervention with CEA or CAS. Commonly cited markers of high stroke risk in relation to ACS lack specificity, have not been assessed in conjunction with current optimal medical intervention, and have not been shown in randomized trials to identify those who benefit from a carotid procedure in addition to current optimal medical intervention. CONCLUSIONS: Medical intervention has an established role in the current routine management of persons with ACS. Stroke risk stratification studies using current optimal medical intervention alone are the highest research priority for identifying persons likely to benefit from adding a carotid procedure
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