799 research outputs found

    Health and Academic Performance With Happy Children: A Controlled Longitudinal Study Based on the HOPP Project

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    BACKGROUND: Overweight/obesity in children and adolescents, largely arising due to increased food intake and reduced physical activity, is a major health concern. Physical activity (PA) integrated into learning has been shown to not only lead to improved health outcomes and wellbeing but also positively affect academic performance. The Health and Academic Performance with Happy Children (HAPHC) project aims at enhancing health and academic performance in elementary school children via implementation of a daily unit of Physical Activity Across the Curriculum (PAAC), which is carried out within the school setting. In this project, PA as an integrated part of learning will be evaluated and the learning material adapted for a large scale implementation across several European countries. METHODS: In three European countries (Austria, Slovenia, and Belgium), 12 primary schools in total will be recruited to act as either intervention or control school in a large intervention study, which applies the PAAC pedagogy during lectures. It is estimated that, at least 3,000+ children across the three countries will be recruited in this study. All teachers of intervention schools will receive training and materials/teaching equipment that will allow them to integrate a daily PA unit of 45 min over 3 years across the curriculum. In response to the daily PA intervention, the following primary outcomes will be assessed: changes in health related physiological factors, academic achievement, psycho-social aspects and wellbeing. IMPACT OF PROJECT: The HAPHC project aims at promoting public health by increasing PA at an early age within the school setting and therewith preventing the increasing risk of non-communicable diseases across Europe. HAPHC project aims to develop knowledge and materials, which will ensure that the PAAC can be scalable to other European countries. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov, identifier: NCT04956003

    A különböző alanyfajták hatása a Cserszegi fűszeres és Bianca borszőlők termésmennyiségére és minőségére

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    A különböző alanyfajták hatása a Cserszegi fűszeres és Bianca borszőlők termésmennyiségére és minőségére. A dolgozatban mérésre kerültek a pH és Brix értékek is. Alany milyen mértékben van hatással a termésre, az adott termesztési célnak megfelelően, figyelembe véve az évjáratot. Ismereteink a génanyagok szűkkörére hivatkozik, ennek bővítésére szolgálnak a mérések. Ezek a mérések egy hosszabbtávú kísérlet alapjai.KertészmérnökBSc/B

    Bianca Garavelli studiosa e scrittrice

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    Bianca Garavelli (Vigevano, 1958-2021) was a highly regarded figure in the literary world, both on the critical and creative side. Author of important critical studies on Dante and of a successful commentary on the Commediam (begun under the supervision of Maria Corti but then continued independently), as well as critic and reviewer for newspapers and periodicals, Garavelli also wrote and published poems, novels and short stories. This article offers an exhaustive bio-bibliographical profile of Bianca Garavelli, whose literary work in various fields is reconstructed and critically examined

    Let´s (watch me) play : which factors relate to Let´s Play addiction?

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    Author Bianca Haun, BScZusammenfassungen in englischer SpracheMasterarbeit Universität Linz 201

    Thyroid functions of mouse cathepsins B, K, and L.

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    Thyroid function depends on processing of the prohormone thyroglobulin by sequential proteolytic events. From in vitro analysis it is known that cysteine proteinases mediate proteolytic processing of thyroglobulin. Here, we have analyzed mice with deficiencies in cathepsins B, K, L, B and K, or K and L in order to investigate which of the cysteine proteinases is most important for proteolytic processing of thyroglobulin in vivo. Immunolabeling demonstrated a rearrangement of the endocytic system and a redistribution of extracellularly located enzymes in thyroids of cathepsin-deficient mice. Cathepsin L was upregulated in thyroids of cathepsin K(-/-) or B(-/-)/K(-/-) mice, suggesting a compensation of cathepsin L for cathepsin K deficiency. Impaired proteolysis resulted in the persistence of thyroglobulin in the thyroids of mice with deficiencies in cathepsin B or L. The typical multilayered appearance of extracellularly stored thyroglobulin was retained in cathepsin K(-/-) mice only. These results suggest that cathepsins B and L are involved in the solubilization of thyroglobulin from its covalently cross-linked storage form. Cathepsin K(-/-)/L(-/-) mice had significantly reduced levels of free thyroxine, indicating that utilization of luminal thyroglobulin for thyroxine liberation is mediated by a combinatory action of cathepsins K and L

    A combined intervention for executive deficits and anxiety in Parkinson's patients: a case study

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    Parkinson’s disease (PD) is a neurodegenerative disorder most commonly associated with motor symptomatology, yet often presenting with deficits in attention, executive functioning (EF; e.g., planning, mental flexibility, complex attention), anxiety, and depression, with debilitating effects on patients’ quality of life. Current interventions, including pharmacological and surgical methods show efficacy in motor symptom management, yet produce equivocal results in addressing non-motor dysfunction. The goal of this paper was to describe and investigate the efficacy and patient acceptance of a nonpharmacological intervention for treatment of executive dysfunction (ED) and anxiety in PD, in the context of a case study (the case of Mr. K). Brain and Mind Fitness Program (BMFP) is a short-term intervention, consisting of a combination of cognitive remediation and cognitive behavioral therapy (CBT). BMFP was demonstrated to be fully acceptable to Mr. K, based on ratings of 4 feasibility dimensions (fatigue, effort, progress, and enjoyment). The program also proved to be efficacious in alleviating Mr. K’s anxiety and depression symptoms, with benefits extending over the treatment period. BMFP, elsewhere shown to be an effective cognitive re-training of EF in PD patients, exhibited limited gains in the case of Mr. K., possibly due to his relatively intact cognitive abilities at baseline. Despite its limitations, the case of Mr. K presents a novel approach to treatment of PD non-motor symptoms and a learning opportunity for researchers and clinicians interested in expanding their knowledge across disciplines.Psy. D.Includes bibliographical referencesby Bianca R. Georgesc

    BIANCA (Brain Intensity AbNormality Classification Algorithm): a new tool for automated segmentation of white matter hyperintensities

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    Reliable quantification of white matter hyperintensities of presumed vascular origin (WMHs) is increasingly needed, given the presence of these MRI findings in patients with several neurological and vascular disorders, as well as in elderly healthy subjects. We present BIANCA (Brain Intensity AbNormality Classification Algorithm), a fully automated, supervised method for WMH detection, based on the k-nearest neighbour (k-NN) algorithm. Relative to previous k-NN based segmentation methods, BIANCA offers different options for weighting the spatial information, local spatial intensity averaging, and different options for the choice of the number and location of the training points. BIANCA is multimodal and highly flexible so that the user can adapt the tool to their protocol and specific needs. We optimised and validated BIANCA on two datasets with different MRI protocols and patient populations (a “predominantly neurodegenerative” and a “predominantly vascular” cohort). BIANCA was first optimised on a subset of images for each dataset in terms of overlap and volumetric agreement with a manually segmented WMH mask. The correlation between the volumes extracted with BIANCA (using the optimised set of options), the volumes extracted from the manual masks and visual ratings showed that BIANCA is a valid alternative to manual segmentation. The optimised set of options was then applied to the whole cohorts and the resulting WMH volume estimates showed good correlations with visual ratings and with age. Finally, we performed a reproducibility test, to evaluate the robustness of BIANCA, and compared BIANCA performance against existing methods. Our findings suggest that BIANCA, which will be freely available as part of the FSL package, is a reliable method for automated WMH segmentation in large cross-sectional cohort studies. © 2016 The Author

    Dataset: Culturally Responsive Supervision

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    Thesis title: A Study Exploring the Supervisory Relationship in the Context of Culturally Responsive Supervision: A Supervisee&rsquo;s Perspective Quantitative and qualitative survey data on supervisee perspectives of culturally responsive supervision and their supervisory relationship. The data was collected by the primary author and can be viewed in SPSS. </span

    Production Performance of ‘Malvaisa Bianca’ grape (Vitis vinifera L.) grown in Subtropical Regions / <br>Comportamento da uva ‘Malvasia Bianca’ (Vitis vinifera L.) cultivada em zona subtropical

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    The objective of this study was to assess the phenotypic/phenology and production performance of ‘Malvasiva Bianca’ grape used to make white wine at North of Parana State. The experiment was done in one vineyard located in Maringa, PR, conducted pergola system accounting with an space of 4.0 X 1.5 m enxert about IAC 766 Campinas. Twenty plants were used previously identified and market during two consecutive harvest seasons (2004/2005 and 2005/2006). The phenotipic performance of grape vives was assessed considering duration of time in days of their principal phases. The chemical characteristics of the berries were assessed performing weekly analysis of pH measurements, Total Solutable Solid (TSS), titratable Acidity (AT) and relationship TSS/TA, starting at the biggining of the maturing process until seven days after harvesting. The production characteristics were assessed considering the average diameter and average mass weight of the berry, number on average of clusters per plant, average mass weight of the cluster and estimates of production and productivity on each plant. The duration of production’s cicle (cutting to harvest) in this region was on average 127 days. Due the harvest period, the pH’s average, SST, AT levels and the relationship SST/AT of the berries ranged were 3.6 ; 21.2 °Brix; 0.6% of Tartaric Acid and 36.0 respectively. The berry presented on average 15.5 mm and 2.2g. It was observed on average 62 clusters per plant, with mass weight of 0.3 Kg; production of 20.0 Kg per plant and productivity of 33.3 t/ha. The results showed that the ‘Malvasia Bianca’ grape presents a great potential to be cultivated for further make aromatic white wine at North of Parana State.O presente trabalho teve como objetivo avaliar o comportamento fenológico e produtivo da uva ‘Malvasia Bianca’ destinada à elaboração de vinhos brancos aromáticos no norte do Paraná. O experimento foi realizado em um vinhedo localizado em Maringá, PR, conduzido em latada em espaçamento de 4,0 x 1,5 m enxertada sobre o IAC 766 Campinas. Foram utilizadas 20 plantas previamente marcadas durante 2 safras consecutivas (2004/2005 e 2005/2006). A fenologia das videiras foi avaliada quanto à duração em dias de suas principais fases. As características químicas do mosto das bagas foram avaliadas por meio de análise semanal do pH, teor de sólidos solúveis totais (SST), acidez titulável (AT) e relação SST/AT, a partir do início da maturação até 7 dias após a colheita. As características da produção foram avaliadas quanto ao diâmetro médio e massa média das bagas, número médio de cachos por planta, massa média dos cachos e estimativas da produção por planta e produtividade. A duração do ciclo (poda à colheita) na região foi em média 127 dias. Por ocasião da colheita, as médias do pH, teor de SST, AT e relação SST/ AT do mosto das bagas foram de 3,6; 21,2 °Brix; 0,6% de ácido tartárico e 36,0, respectivamente. As bagas apresentaram em média 15,5 mm e 2,2g. Observou-se em média 62 cachos por planta, com massa de 0,3 kg; produção de 20,0 kg/planta e produtividade de 33,3 t/ha. Pelos resultados obtidos, verifica-se que a uva ‘Malvasia Bianca’ apresenta um promissor potencial de cultivo para a elaboração de vinhos brancos aromáticos no norte do Paraná
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