1,721,330 research outputs found

    Boon, M. C.

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    The efficacy of using the tissue fragments present in cervical scrapes for the histologic diagnosis of cervical neoplasia

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    Cervical scrapes to diagnose cervical neoplasia, collected by the clinician with brushes, are sent to the Leiden Cytology and Pathology Laboratory (LCPL) in vials containing BoonFix, a noncross-linking coagulant fixative. Because the residual material left in the vials contains tissue fragments with important diagnostic information, we stored the residual material in our archives. The tissue fragments can be mummified and archived in commercially available histology cassettes. We can produce paraffin sections thereof. Immunostaining is beautiful on serial paraffin sections cut from these blocks. We experienced that it is important to leave the brush in the vial such that all tissue fragments can be used for histologic diagnosis. In order to optimize the system, tissue fragments left in the endocervical part of the brush are removed in a paint shaker. We illustrate this principle of recovering mummified tissue fragments in a false negative case with cytology containing many undiagnosable collapsed tissue fragments. This case shows clearly the efficacy of using the tissue fragments present in cervical scrapes for the histologic diagnosis of cervical neoplasia. © 2013 Lifescience Global

    Experimenteel onderzoek naar het effect van Ground Consolidators op golven (Anome)

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    Onderzoek uitgevoerd in het Laboratorium voor Vloeistofmechanica van de TU Delft van 9 november tot 18 december 2009. Dit rapport bevat de meetresultaten en conclusies van proeven met GC’s (Ground Consolidators) die zijn uitgevoerd in november en december 2009 in het Laboratorium voor Vloeistofmechanica van de TU Delft. Het doel van de proeven is het verkrijgen van inzicht in de hydraulische eigenschappen van GC’s en de optimale vorm van een GC-kunstrif onder golfbelasting. De proeven zijn uitgevoerd ter voorbereiding op de bouw van een kunstrif bestaande uit GC’s in de Waterproeftuin. Dit is een proefgebied in het Markermeer waar initiatiefnemers de gelegenheid wordt geboden om ervaring op te doen met innovatieve materialen en technieken. De Waterproeftuin is een onderdeel van het Ontwikkelingsplan Markermeer-IJmeer, ter ontwikkeling van een gezond ecologisch systeem en een klimaatbestendig watersysteem in het Markermeer en IJmeer. Er is gekozen voor een aanpak met ‘bouwblokken’, waarbij een rif opgebouwd wordt uit elementen gevuld met GC’s. Op die manier wordt een dataset verkregen voor een aantal elementaire vormen. Een opdrachtgever hoeft dan slechts zijn eisen op te geven en in korte tijd kan een GC constructie ‘ in elkaar gezet’ worden, zonder dat daar nog veel ontwerp tijd in gaat zitten. In dit rapport staan de resultaten van de uitgevoerde proeven en de conclusies die daaruit voortgekomen zijn. In hoofdstuk 2 wordt ingegaan op de proeven die gericht waren op golfreductie. Voor verschillende constructies, waterstanden en golfhoogtes is de golfhoogte voor en na de constructie gemeten. In hoofdstuk 3 zijn de verdichtingsproeven uitgewerkt. De gebruikte constructies bestaan uit frames van betongaas die gevuld zijn met GC’s. Door het tellen van de hoeveelheid GC’s die erin paste, kon de verdichting bepaald worden. De resultaten van de snelheidsmetingen worden behandeld in hoofdstuk 4. In hoofdstuk 5 worden de valproeven toegelicht. Boven een grote glazen bak gevuld met water zijn GC’s losgelaten. Met behulp van video-opnames is de valsnelheid van GC’s in water bepaald.Hydraulic EngineeringCivil Engineering and Geoscience

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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