660 research outputs found
Characterization of Colloidal Drug Carriers
No full textHydrophobic interaction chromatography (HIC) is presented as a suitable method to determine the surface hydrophobicity of colloidal drug carriers. The experimental design is described in great detail. Results obtained with surface-modified polystyrene particles as model carriers and parenteral fat emulsions are discussed as examples. HIC was able to distinguish between particles chemically modified by the introduction of functional groups. Polystyrene particles of various size were surface-modified by adsorption of the block-polymer Poloxamine 908. HIC distinguished between the hydrophobicities of these adsorption layers. The measured surface hydrophobicities of particles and fat emulsions were well in agreement with the in vivo organ distribution data obtained after i. v. injection of the carriers
Entwicklung einer schnellen Pulsformanalyse für asymmetrische AGATA-Germanium-Detektoren
No full textOnTEAM metadata: GDSID: DOC-2007-May-32; Attribute ID: LIBRARY-thesis_diss-2007-005; Title: [GSI Diss 2007-05] Entwicklung einer schnellen Pulsformanalyse für asymmetrische AGATA-Germanium-Detektoren; Author(s): Beck, Torsten; Corporate author(s): ; Publication date: 20070501; Creator: manton; Creation date: 15.05.2007 16:02:12; Change date: 29.10.2008 16:29:34; Access: nur berechtigte Gruppen; Attribute type: Text.Thesis.Diss; Directory path: ['GSI Publications', 'GSI as Publisher']; Attribute path: ['Infrastructure', 'Library and Documentation', 'thesis_diss', 'Added in 2007']; File name(s): ['DOC-2007-May-32-1.pdf']; File title(s): ['']; File access: ['nur berechtigte Gruppen'
Manifolds, sheaves, and cohomology
No full textThis book explains techniques that are essential in almost all branches of modern geometry such as algebraic geometry, complex geometry, or non-archimedian geometry. It uses the most accessible case, real and complex manifolds, as a model. The author especially emphasizes the difference between local and global questions. Cohomology theory of sheaves is introduced and its usage is illustrated by many examples. Content Topological Preliminaries - Algebraic Topological Preliminaries - Sheaves - Manifolds - Local Theory of Manifolds - Lie Groups - Torsors and Non-abelian Cech Cohomology - Bundles - Soft Sheaves - Cohomology of Complexes of Sheaves - Cohomology of Sheaves of Locally Constant Functions - Appendix: Basic Topology, The Language of Categories, Basic Algebra, Homological Algebra, Local Analysis Readership Graduate Students in Mathematics / Master of Science in Mathematics About the Author Prof. Dr. Torsten Wedhorn, Department of Mathematics, Technische Universität Darmstadt, Germany
James Watson, Maclyn McCarty, and Torsten Wiesel
No full textTorsten Wiesel (right) with Professor Emeritus Maclyn McCarty (center), co-author of the paper with Oswald Avery and Colin MacLeod, and James D. Watson, director of Cold Spring Harbor Laboratory, 1994
Photo by Leif Carlsson
To commemorate the fiftieth anniversary of the discovery at The Rockefeller University that genes are made of DNA - considered by many to be the single most important biological discovery of the twentieth century - the university has kicked off a year-long series of events that were running through May 1994. The celebration was formally inaugurated in November 1993 with a lecture by Nobel laureate James D. Watson, best known for discovering the double-helical structure of DNA.
See also Search Winter 1994, vol. 4, no. 1https://digitalcommons.rockefeller.edu/group-portraits/1013/thumbnail.jp
Shaping Synthetic Multicellular and Complex Multimaterial Tissues via Embedded Extrusion‐Volumetric Printing of Microgels
No full textIn living tissues, cells express their functions following complex signals from their surrounding microenvironment. Capturing both hierarchical architectures at the micro- and macroscale, and anisotropic cell patterning remains a major challenge in bioprinting, and a bottleneck towards creating physiologically-relevant models. Addressing this limitation, we introduced a novel technique, termed Embedded Extrusion-Volumetric Printing (EmVP), converging extrusion-bioprinting and layer-less, ultra-fast volumetric bioprinting, allowing to spatially pattern multiple inks/cell types. Light-responsive microgels were developed for the first time as bioresins (μResins) for light-based volumetric bioprinting, providing a microporous environment permissive for cell homing and self-organization. Tuning the mechanical and optical properties of gelatin-based microparticles enables their use as support bath for suspended extrusion printing, in which features containing high cell densities can be easily introduced. μResins can be sculpted within seconds with tomographic light projections into centimetre-scale, granular hydrogel-based, convoluted constructs. Interstitial microvoids enhanced differentiation of multiple stem/progenitor cells (vascular, mesenchymal, neural), otherwise not possible with conventional bulk hydrogels. As proof-of-concept, EmVP was applied to create complex synthetic biology-inspired intercellular communication models, where adipocyte differentiation is regulated by optogenetic-engineered pancreatic cells. Overall, EmVP offers new avenues for producing regenerative grafts with biological functionality, and for developing engineered living systems and (metabolic) disease models
Seltsame Schauspiele. Torsten Fogelqvists Deutschlandreise 1934
No full textIn 1934 Torsten Fogelqvist, a prominent member of the Swedish Academy and a well-known journalist and intellectual, visits Nazi Germany. He writes about his visit to the Third Reich in 17 articles published in the Stockholm daily newspaper Dagens Nyheter. The author, highly critical of the Hitler regime, scrutinizes several aspects of the nazified German society such as the attempts to re-educate the German citizen in accordance with the ideology of the new regime, the hero cult in the Nazi movement, and the relationship between the German state and the churches. In order to further an understanding of political and social developments in Germany Fogelqvist uses a specific strategy. He “translates” them into an imaginary Swedish context. This paper compares his views with those of other Swedish visitors
PISM glacial cycle sensitivity experiments of the Antarctic Ice Sheet
No full textThis dataset contains PISM simulation results (http://www.pism-docs.org) of the Antarctic Ice Sheet based on code release v1.0-paleo-ensemble (https://doi.org/10.5281/zenodo.3574033). PISM is the open-source Parallel Ice Sheet Model developed mainly at UAF, USA and PIK, Germany.
With the help of added python scripts, all figures can be reproduced as in the journal publication:
- Albrecht et al., 2020, doi:10.5194/tc-14-599-2020.
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Data:
Find PISM results as netCDF data. See 'README.md' for a list of all performed experiment.
All forcing input data for the experiments and plots can be downloaded and remapped via https://github.com/pism/pism-ais. Some of the original input data files are freely available, for others please contact the author or the corresponding data publisher.
Figure plotting scripts (jupyter notebook based on python, see https://jupyter.org) in 'plot_scripts' access the uploaded PISM results in 'model_data' and save the plots to 'final_figures'. Jupyter notebook can be run in the browser and shared, see https://nbviewer.jupyter.org/url/www.pik-potsdam.de/~albrecht/notebooks/paleo_paper/paleo_paper_final.ipynb.
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Contact:
Albrecht, Torsten ([email protected]) ; Potsdam-Institute for Climate Impact Research (PIK), Potsdam, German
Die Erfolgsfaktoren für unternehmerisches E-Mail-Marketing nach Dr. Torsten Schwarz am Praxisbeispiel ERGOTOPIA GmbH
No full textThis scientific document reveals the results of an empirical examination within the realm of entrepreneurial e-mail-marketing which is based on a literature review by technical author Dr. Torsten Schwarz. Using the start-up company ERGOTOPIA as a practical example, the author of the master thesis investigates whether the explanations of Dr. Schwarz match with the practical implementation of ERGOTOPIA.
Precisely, the scientific paper focuses on the examination of the four aspects lead generation, newsletter-design, software-requirements and performance measurement through monitoring with regard to successful realization of e-mail-marketing campaigns. The empirical part of this examination is made of the introduction as well as the analysis of two conducted so called split-tests that compare specific aspects of the newsletter-design and measure data-driven results to show which kind of aspect produced the more successful campaign.
This way the author proves whether the recommendations by Dr. Schwarz are practically relevant for the company ERGOTOPIA
Plasmaproteinadsorption auf kolloidalen Arzneistoffträgern. Analytik, Korrelation mit Oberflächeneigenschaften, Implikationen für das Drug Targeting
No full textInvitation to Dialogue - A Progress Report
No full textFragmentation of knowledge and life milieux, so often associated with specialization in science and planning, provided the broad challenge in science and planning, provided the broad challenge for a DIALOGUE PROJECT initiated by Torsten Hägerstrand and Anne Buttimer in Sweden during the Academic Years 1977-1979. The initial incentive for confronting such a wide-ranging set of issues arose from a paper on Values in Geography (Buttimer, 1974), after which the author was invited as a Fulbright lecturer to offer a series of seminars in Lund on problems of knowledge and experience. More than forty participants from ten widely different disciplines took part in this seminar, and foundations were laid for an experientially-grounded approach to the problems of communication across disciplines. The present project was initiated when Anne Buttimer was invited to accept a full time position in Sweden by the Humanistisk-Samhällsvetenskapliga Forskningsrådet (Council for Humanities and Social Science) in 1977. Financial support for this pilot phase of the Dialogue Project was granted by the Swedish Committee for Future Oriented Research and the Bank of Sweden Tercentenary Foundation. The geography department at the University of Lund continues to provide material and administrative help, with Torsten Hägerstrand as Co-Director
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