1,721,195 research outputs found
Leptin inhibits the anti-CD3-driven proliferation of peripheral blood T cells but enhances the production of proinflammatory cytokines.
Intramural distribution of neuron specific enolase (NSE) in the human gastrointestinal tract.
NSE concentrations were measured by radioimmunoassay in the main separated layers
of the human gastrointestinal tract. At all levels, a similar pattern of
distribution of this protein was found, primarily parallel to that of nerve
elements. Lower amounts of NSE were detected in the separated mucosal epithelium,
containing the endocrine cells
Development of neuroendocrine tumors in the gastro-intestinal tract of transgenic mice: heterogeneity of hormone expression.
AM J PATHO
Ileal enteroglucagon cells after ileal-duodenal transposition in the rat.
The changes occurring in the ileal wall and in enteroglucagon cells were studied
in a rat model of intestinal adaptation, obtained by the transposition of a
segment of distal ileum into the mid-duodenum (6 rats, compared with 6 transected
controls). After 40 days, the transposed ileal segment, compared to the
equivalent segment in the controls, showed striking increase in weight,
especially of the epithelium (1,585 +/- 127 vs. 305 +/- 42 mg, mean +/- SEM, p
less than 0.0005). The calculated weight of enteroglucagon cells in the segment
showed a smaller, but significant increase (1.7 +/- 0.3 vs. 0.8 +/- 0.2
micrograms, p less than 0.05). Plasma enteroglucagon was markedly raised (239 +/-
28 vs. 61 +/- 7.1 pmol/l, p less than 0.0005) and showed a greatly increased
meal-stimulated response (1,521 +/- 284 vs. 83 +/- 43 pmol, p less than 0.0005),
thus suggesting hyperactivity of enteroglucagon cells
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression.
Neuropeptides and 5-HT immunoreactivity in the gastric nerves of the dogfish (Scyliorhinus stellaris). Peptides. 1985;6 Suppl 3:373-7
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