1,721,195 research outputs found

    Bloom, SR

    No full text

    Intramural distribution of neuron specific enolase (NSE) in the human gastrointestinal tract.

    No full text
    NSE concentrations were measured by radioimmunoassay in the main separated layers of the human gastrointestinal tract. At all levels, a similar pattern of distribution of this protein was found, primarily parallel to that of nerve elements. Lower amounts of NSE were detected in the separated mucosal epithelium, containing the endocrine cells

    Ileal enteroglucagon cells after ileal-duodenal transposition in the rat.

    No full text
    The changes occurring in the ileal wall and in enteroglucagon cells were studied in a rat model of intestinal adaptation, obtained by the transposition of a segment of distal ileum into the mid-duodenum (6 rats, compared with 6 transected controls). After 40 days, the transposed ileal segment, compared to the equivalent segment in the controls, showed striking increase in weight, especially of the epithelium (1,585 +/- 127 vs. 305 +/- 42 mg, mean +/- SEM, p less than 0.0005). The calculated weight of enteroglucagon cells in the segment showed a smaller, but significant increase (1.7 +/- 0.3 vs. 0.8 +/- 0.2 micrograms, p less than 0.05). Plasma enteroglucagon was markedly raised (239 +/- 28 vs. 61 +/- 7.1 pmol/l, p less than 0.0005) and showed a greatly increased meal-stimulated response (1,521 +/- 284 vs. 83 +/- 43 pmol, p less than 0.0005), thus suggesting hyperactivity of enteroglucagon cells
    corecore