105,425 research outputs found
Microscleroderma lamina Perez, Vacelet, Bitar & Zibrowius 2004
No full text<i>Microscleroderma lamina</i> Perez, Vacelet, Bitar & Zibrowius, 2004 <p>MNHN D JV 76-77-78, Levant basin, N-Lebanon, Chak El Hatab, lithistid dark cave, 34°17’63N 35°40’27E, 2 m of depth, 21.ix.2002, G. Bitar and H. Zibrowius leg., SCUBA diving, dry/formalin/alcohol (Perez et al. 2004)</p> <p>Distribution: Only known from the type locality an E-Mediterranean cave.</p>Published as part of <i>Manconi, Renata & Serusi, Annalisa, 2008, Rare sponges from marine caves: discovery of Neophrissospongia nana nov. sp. (Demospongiae, Corallistidae) from Sardinia with an annotated checklist of Mediterranean lithistids, pp. 71-87 in ZooKeys 4 (4)</i> on page 84, DOI: 10.3897/zookeys.4.39, <a href="http://zenodo.org/record/576426">http://zenodo.org/record/576426</a>
Gastrophanella phoeniciensis Perez, Vacelet, Bitar & Zibrowius 2004
No full text<i>Gastrophanella phoeniciensis</i> Perez, Vacelet, Bitar & Zibrowius, 2004 <p>MNHN D JV 73-74-75, Levant basin, N-Lebanon, Chak El Hatab, Lithistid cave, 34°17’63N 35°40’27E, 21.IX.2002, G. Bitar and H. Zibrowius leg., 2 m of depth, SCUBA diving, formalin/alcohol (Perez et al. 2004)</p> <p>Distribution: Only known from the type locality an E-Mediterranean cave.</p>Published as part of <i>Manconi, Renata & Serusi, Annalisa, 2008, Rare sponges from marine caves: discovery of Neophrissospongia nana nov. sp. (Demospongiae, Corallistidae) from Sardinia with an annotated checklist of Mediterranean lithistids, pp. 71-87 in ZooKeys 4 (4)</i> on page 86, DOI: 10.3897/zookeys.4.39, <a href="http://zenodo.org/record/576426">http://zenodo.org/record/576426</a>
Biogeographical homogeneity in the eastern Mediterranean Sea. II. temporal variation in lebanese bivalve biota
No full textLebanon (eastern Mediterranean Sea) is an area of particular biogeographic signifi-cance for studying the structure of eastern Mediterranean marine biodiversity and its recent changes. Based on literature records and original samples, we review here the knowledge of the Lebanese marine bivalve biota, tracing its changes during the last 170 yr. The updated checklist of bivalves of Lebanon yielded a total of 114 species (96 native and 18 alien taxa), accounting for ca. 26.5% of the known Mediterranean Bivalvia and thus representing a particularly poor fauna. Analysis of the 21 taxa historically described on Lebanese material only yielded 2 available names. Records of 24 species are new for the Lebanese fauna, and Lioberus ligneus is also a new record for the Mediterranean Sea. Comparisons between molluscan records by past (before 1950) and modern (after 1950) authors revealed temporal variations and qualitative modifications of the Lebanese bivalve fauna, mostly affected by the introduction of Erythraean species. The rate of recording of new alien species (evaluated in decades) revealed later first local arrivals (after 1900) than those observed for other eastern Mediterranean shores, while the peak in records in conjunc-tion with our samplings (1991 to 2010) emphasizes the need for increased field work to monitor their arrival and establishment. Finally, the scarce presence (or total absence) in the most recent samples of some once common habitat-forming species, as well as of some other native taxa, con-firmed their recent rarefaction (or local extinction), possibly related to their replacement by the aliens Brachidontes pharaonis, Spondylus spinosus and Chama pacifica. © Inter-Research 2013
Effect of chronic hypoxia on leptin, insulin, adiponectin, and ghrelin
No full textThe endocrine system plays an important role in the adaptation to hypoxia. The aim of this study was to assess the effect of chronic hypoxia on insulin, adiponectin, leptin, and ghrelin levels in a neonatal animal model. Sprague-Dawley rats were placed in a normobaric hypoxic environment at birth. Controls remained in room air. Rats were killed at 2 and 8 weeks of life. Insulin, adiponectin, leptin, and ghrelin were measured. At 2 weeks of life, there was no significant difference in insulin, adiponectin, and leptin levels between the hypoxic and control rats. The only statistically significant difference was found in ghrelin levels, which were lower in the hypoxic group (3.19 ± 3.35 vs 24.52 ± 5.09 pg-mL; P .05). At 8 weeks of life, insulin was significantly higher in the hypoxic group (0.72 ± 0.14 vs 0.44 ± 0.26 ng-mL; P .05) and adiponectin was significantly lower (1257.5 ± 789.5 vs 7817.3 ± 8453.7 ng-mL; P .05). Leptin and ghrelin did not show significant difference in this age group, but leptin level per body weight was higher in the hypoxic group. Finally, we conclude that 2 weeks of continuous neonatal hypoxic exposure leads to a decrease in plasma ghrelin only with no significant change in insulin, adiponectin, and leptin and that 8 weeks of hypoxia leads to a decrease in adiponectin with an increase in insulin despite a significant decrease in weight. © 2008 Elsevier Inc. All rights reserved.Ambrosini G, 2002, J BIOL CHEM, V277, P34601, DOI 10.1074-jbc.M205172200; BAUM D, 1969, J CLIN ENDOCR METAB, V29, P991; BAUM D, 1976, ENDOCRINOLOGY, V98, P359; Bennett BD, 1996, CURR BIOL, V6, P1170, DOI 10.1016-S0960-9822(02)70684-2; Bitar FF, 2002, PEDIATR RES, V51, P144, DOI 10.1203-00006450-200202000-00005; BITAR FF, 1994, J SURG RES, V57, P264, DOI 10.1006-jsre.1994.1142; Bornstein SR, 1998, J CLIN ENDOCR METAB, V83, P280, DOI 10.1210-jc.83.1.280; Braun B, 2001, J APPL PHYSIOL, V91, P623; Considine RV, 1996, NEW ENGL J MED, V334, P292, DOI 10.1056-NEJM199602013340503; Dagogo-Jack S, 1998, KIDNEY INT, V54, P997, DOI 10.1046-j.1523-1755.1998.00077.x; GALLON V, 1972, ENDOCRINOLOGY, V91, P1393; GARVEY D, 1979, J ENDOCRINOL, V80, P333, DOI 10.1677-joe.0.0800333; GOSNEY J, 1991, INT J BIOMETEOROL, V35, P1, DOI 10.1007-BF01040955; GOSNEY JR, 1986, J ENDOCRINOL, V109, P119, DOI 10.1677-joe.0.1090119; Grosfeld A, 2002, DIABETOLOGIA, V45, P527, DOI 10.1007-s00125-002-0804-y; HEALTH D, 1981, ENDOCRINES MAN HIGH, P250; HERMANS RHM, 1994, PHYSIOL BEHAV, V55, P469, DOI 10.1016-0031-9384(94)90102-3; JACOBS R, 1988, J DEV PHYSIOL, V10, P97; Kershaw EE, 2004, J CLIN ENDOCR METAB, V89, P2548, DOI 10.1210-jc.2004-0395; Larsen JJ, 1997, J PHYSIOL-LONDON, V504, P241, DOI 10.1111-j.1469-7793.1997.241bf.x; Meissner U, 2003, BIOCHEM BIOPH RES CO, V303, P707, DOI 10.1016-S0006-291X(03)00401-7; Mise H, 1998, J CLIN ENDOCR METAB, V83, P3225, DOI 10.1210-jc.83.9.3225; MORDES JP, 1983, NEW ENGL J MED, V308, P1135, DOI 10.1056-NEJM198305123081906; Raff H, 2001, HORM METAB RES, V33, P151, DOI 10.1055-s-2001-14929; Raff H, 2003, ENDOCRINE, V21, P159, DOI 10.1385-ENDO:21:2:159; Sagawa N, 2002, PLACENTA, V23, pS80, DOI 10.1053-plac.2002.0814; Tillmar L, 2002, MOL MED, V8, P263; Tschop M, 2001, ADV EXP MED BIOL, V502, P237; Tschop M, 1998, LANCET, V352, P1119, DOI 10.1016-S0140-6736(05)79760-9; Westerterp KR, 2001, NEWS PHYSIOL SCI, V16, P134; Wolk R, 2005, OBES RES, V13, P186, DOI 10.1038-oby.2005.24; Yasumasu T, 2002, OBES RES, V10, P128, DOI 10.1038-oby.2002.20; Yasumasu T, 2002, OBES RES, V10, P857, DOI 10.1038-oby.2002.117; ZAYOUR D, 2003, ENDOCR RES, V29, P9116111
Biogeographical homogeneity in the eastern Mediterranean Sea - I: The opisthobranchs (Mollusca: Gastropoda) from Lebanon
No full textA review of opisthobranch species from Lebanon (eastern Mediterranean Sea), based on literature records (scattered throughout various papers published over a period of more than 150 years) and recently collected material (1999-2002 within the CEDRE framework and other samples), is presented, yielding a total number of 35 taxa identified to species level. Special emphasis has been placed on alien species, for which scattered notes are also given. The known opisthobranch biota is composed of 22 native (~ 63%), 12 alien (~ 34%) and one cryptogenic (~ 3%) taxa. Eleven of these (Berthella aurantiaca, Berthella ocellata, Aplysia fasciata, Felimare picta, Felimida britoi, Felimida luteorosea, Felimida purpurea, Phyllidia flava, Dendrodoris grandiflora, Dendrodoris limbata and Aeolidiella alderi) constitute new records for the Lebanese fauna, whilst the examined material of a further seven species (Elysia grandifolia, Pleurobranchus forskalii, Aplysia dactylomela, Bursatella leachii, Syphonota geographica, Goniobranchus annulatus, Flabellina rubrolineata), anecdotally cited from Lebanon on the basis of the samples studied here, is explained for the first time. One additional taxon belonging to the genus Haminoea has been identified to genus level only
Increase in knowledge of the marine gastropod fauna of Lebanon since the 19th century
No full textWe hereby review and update the current state of knowledge on the Lebanese gastropod biota based on published literature and the study of new samples. Review of 1543 published records yielded 237 gastropod taxa. New samples from the Lebanese coast yielded 2414 living specimens and 4003 empty shells, belonging to 188 taxa. Forty-six of the taxa are new records for the Lebanese fauna, bringing the gastropods known from Lebanon to 283 species. Literature records also included 71 nominal gastropod taxa based on type material from Lebanon, including 3 genera, 8 species, and 60 subspecific units. Of these, only 13 are retained as available. Of the 283 gastropod taxa known from Lebanon, 41 are aliens and 7 are cryptogenic. The majority of nonnative taxa were recorded only during the last decades, particularly from 1980 to 2019. Results from the present study question the common assumption that this region has extremely low native diversity. The flora and fauna of the Lebanese coast remain relatively unexplored and our data support the perception that several formerly abundant species have recently collapsed. Despite these advances, the lack of scientific data on biodiversity and community structure of Lebanese habitats and geographic zones is likely to hamper conservation actions and legal protection of critical species. We therefore recommend additional field and laboratory research to increase knowledge of both taxonomic composition and species’ distributions in Lebanon and elsewhere in the easternmost Mediterranean Sea
Regulation of the sphingolipid signaling pathways in the growing and hypoxic rat heart
No full textSphingolipids (SLs) have a biomodulatory role in physiological as well as pathological cardiovascular conditions. This study aims to assess the variation of SL mediators and metabolizing enzymes in the growing and hypoxic rat heart. Sprague-Dawley rats were placed in a hypoxic environment at birth. Control animals remained in room air. In control animals, activities of acidic-sphingomyelinase (A-SMase), sphingomyelin synthase (SMS), glucosylceramide synthase (GCS), and ceramidase decreased with age in both ventricles whereas activity of neutral-sphingomyelinase (N-SMase) increased with age. Hypoxic RV mass was 171 and 229percent that of controls, at 4 and 8 weeks, respectively. This was accompanied by an increase in RV myocardial ceramide synthesis, consumption and breakdown, with a net effect of suppression of ceramide accumulation and increase in diacylglycerol (DAG) concentration. In addition, significant increase in activities of: A-SMase by 26 and 29percent, SMS by 108 and 40percent, and ceramidase by 66 and 35percent, in the hypoxic RV rats as compared to controls, was noted at 4 and 8 weeks of age, respectively. Sphingolipids and their regulating enzymes appear to play a role in adaptive responses to chronic hypoxia in the neonatal rat heart. © 2005 Elsevier Inc. All rights reserved.AMES BN, 1960, J BIOL CHEM, V235, P769; Bielawska A, 1996, J BIOL CHEM, V271, P12646; Bitar FF, 2002, PEDIATR RES, V51, P144, DOI 10.1203-00006450-200202000-00005; BITAR FF, 1994, J SURG RES, V57, P264, DOI 10.1006-jsre.1994.1142; BLIGH EG, 1959, CAN J BIOCHEM PHYS, V37, P911; Dbaibo GS, 1998, APOPTOSIS, V3, P317, DOI 10.1023-A:1009668802718; De Maria R., 1997, SCIENCE, V277, P1652; EXTON JH, 1994, BBA-LIPID LIPID MET, V1212, P26, DOI 10.1016-0005-2760(94)90186-4; FOLCH J, 1957, J BIOL CHEM, V226, P497; Hannun YA, 1996, SCIENCE, V274, P1855, DOI 10.1126-science.274.5294.1855; Hernandez OM, 2000, CIRC RES, V86, P198; KAJSTURA J, 1995, EXP CELL RES, V219, P110, DOI 10.1006-excr.1995.1211; Liliom K, 2001, BIOCHEM J, V355, P189, DOI 10.1042-0264-6021:3550189; Luberto C, 1998, J BIOL CHEM, V273, P14550, DOI 10.1074-jbc.273.23.14550; Moravec M, 2002, BASIC RES CARDIOL, V97, P153, DOI 10.1007-s003950200006; O'Brien NW, 2003, CIRC RES, V92, P589, DOI 10.1161-01.RES.0000066290.29715.67; Olivera A, 2000, METHOD ENZYMOL, V311, P215; PREISS J, 1986, J BIOL CHEM, V261, P8597; Rudolph AM, 1999, PEDIATR RES, V46, P141, DOI 10.1203-00006450-199908000-00002; SIAKOTOS AN, 1969, LIPIDS, V4, P239, DOI 10.1007-BF02532639; Spiegel S, 2002, J BIOL CHEM, V277, P25851, DOI 10.1074-jbc.R200007200; VANVELDHOVEN PP, 1989, ANAL BIOCHEM, V183, P177, DOI 10.1016-0003-2697(89)90186-3; YAVIN E, 1969, BIOCHEMISTRY-US, V8, P1692, DOI 10.1021-bi00832a052; Zayour D, 2003, ENDOCR RES, V29, P191, DOI 10.1081-ERC-120022301; Zhang DX, 2001, BASIC RES CARDIOL, V96, P267, DOI 10.1007-s00395017005797
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Revise and remember : managing hip resurfacing implant recall [Elektronisk resurs]
No full textBackground Total hip arthroplasty (THA) with metal-on-polyethylene articulation provides excellent clinical outcomes but remains associated with complications such as polyethylene wear and joint dislocations. For younger and more active patients, metal-on-metal (MoM) implants were initially introduced as a promising alternative. However, MoM bearings have subsequently demonstrated higher complication rates, including severe adverse events such as periprosthetic fractures and soft tissue reactions in the joint. One such implant with particularly high complication rates was the Articular Surface Replacement (ASR) by DePuy/Johnson&Johnson. As a result, the use of MoM implants declined in Sweden by 2015, and the Swedish Hip and Knee Society officially ceased recommending hip resurfacing arthroplasty in 2018. This decision started a debate in the media between pro and con groups for HRA. Adding further complexity, certain European countries have continued to perform the procedure, with follow-up challenges affecting the Swedish healthcare system. Investigating the implications of MoM implants on patients' outcomes and healthcare systems is essential for future clinical guidelines and policy decisions. Methods Paper I and III studied patients' experiences with the ASR hip resurfacing arthroplasty (HRA). Paper I focused on those living with the recalled implant, while Paper III examined the narratives of patients undergoing revision surgery due to complications. Paper Il compared long-term revision rates, clinical outcomes, and changes in blood metal ion levels between patients with ASR THA and those with ASR HRA. Paper IV investigated potential socioeconomic differences in patients receiving MoM HRA versus uncemented THA in a 1:1 matched ratio from 1999 to 2014. Results Patients living with asymptomatic ASR HRA implants without pain reported that they rarely thought about the implant. Many had actively sought referrals to centers performing HRA procedures. Annual hospital check-ups after surgery were highly valued by these patients, and if the patients were taken care of and informed, they continued to express their trust in the healthcare system. Among patients who underwent revision surgery, some were satisfied with their new implants, while others continued to experience pain and further complications. Despite the recall, since the patients were well taken care of, trust in the healthcare system remained intact. In a cohort of 38 patients, 11-year outcomes revealed no revisions among ASR HRA recipients, but 32% of ASR XL THA recipients required revision surgery. The ASR XL THA group also exhibited significantly elevated cobalt ion levels, even in well-functioning implants. Patients with lower education and income levels were more likely to receive uncemented THA than MoM HRA. Conclusion When an implant is recalled due to high complication rates, robust support systems, including annual follow-ups, are crucial. Patients emphasized the importance of transparent communication regarding implant risks. ASR XL THA demonstrated poorer outcomes compared to ASR HRA, with rising cobalt ion levels in asymptomatic patients, necessitating regular monitoring. Socioeconomic differences in implant selection challenge the principle of equitable healthcare, warranting further attention. List of scientific papers I. Living with a recalled implant: a qualitative study of patients' experiences with ASR hip resurfacing arthroplasty. Bitar C, Krupic F, Felländer-Tsai L, Crnalic S, Wretenberg P. Patient Saf Surg. 2021;15(1):2. https://doi.org/10.1186/s13037-020-00278-y II. 11-Year outcomes in patients with metal-on-metal ASR hip arthroplasty. Bitar C, Moberg I, Krupic F, Wretenberg P, Otten V, Crnalic S. J Orthop. 2022;32:98-103. https://doi.org/10.1016/j.jor.2022.05.015 III. Beyond the procedure of a recalled implant: Patients' experiences of ASR hip implant revision. Bitar C, Wretenberg P, Felländer-Tsai L, Crnalic S, Krupic F. [Submitted] IV. Socioeconomic disparities in the utilization of metal-on-metal hip resurfacing compared to uncemented total hip arthroplasty: A population-based case-control study in Sweden. Oxblom A, Bitar C, Rolfson O, Hedlund H, Qureshi AR, Brismar H, Wretenberg P, Palme M, Adami J, and Felländer-Tsai L. [Submitted
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