7 research outputs found
Reaching the elderly: understanding of health and preventive experiences for a tailored approach - results of a qualitative study
No full textBACKGROUND Often preventive measures are not accessed by the people who were intended to be reached. Programs for older adults may target men and women, older adults, advanced old age groups and/or chronically ill patients with specific indications. The defined target groups rarely participate in the conception of programs or in the design of information materials, although this would increase accessibility and participation. In the German "Reaching the Elderly" study (2008-2011), an approach to motivating older adults to participate in a preventive home visit (PHV) program was modified with the participatory involvement of the target groups. The study examines how older men and women would prefer to be addressed for health and prevention programs.
METHODS Four focus groups (N = 42 participants) and 12 personal interviews were conducted (women and men in 2 age groups: 65-75 years and ≥ 76 years). Participants from two districts of a major German city were selected from a stratified random sample (N = 200) based on routine data from a local health insurance fund. The study focused on the participants' knowledge about health and disease prevention and how they preferred to be approached and addressed. Videos of the focus groups were recorded and analysed using mind mapping techniques. Interviews were digitally recorded, transcribed verbatim and subjected to qualitative content analysis.
RESULTS A gender-specific approach profile was observed. Men were more likely to favor competitive and exercise-oriented activities, and they associated healthy aging with mobility and physical activity. Women, on the other hand, displayed a broader understanding of healthy aging, which included physical activity as only one aspect as well as a healthy diet, relaxation/wellness, memory training and independent living; they preferred holistic and socially oriented services that were not performance-oriented. The "older seniors" (76+) were ambivalent towards certain wordings referring to aging.
CONCLUSIONS Our results suggest that gender-specific needs must be considered in order to motivate older adults to participate in preventive services. Age-specific characteristics seem to be less relevant. It is more important to pay attention to factors that vary according to the individual state of health and life situation of the potential participants
Schwerpunktbericht: Gesundheit von Frauen und Männern im mittleren Lebensalter
No full textZahlreiche Geschlechtsunterschiede sind für die Planung geschlechtergerechter Versorgungsangebote im mittleren Lebensalter relevant. Im Alter zwischen 30 und 65 Jahren ist die Sterblichkeit bei Männern doppelt so hoch wie bei Frauen, was vor allem auf Herzkreislauferkrankungen sowie Unfälle und Suizide zurückzuführen ist. Frauen geben dagegen eine schlechtere körperliche und psychische Befindlichkeit an
Residential proximity to oil and gas production sites and hematologic malignancies: A case‐control study
No full textBackground We investigated the association between residential proximity to oil and gas production sites and hematologic malignancies, due to a cancer cluster in the German state of Lower Saxony. Methods A registry-based case-control study was conducted including 3978 cases of hematologic malignancies diagnosed within 2013-2016 and 15,912 frequency-matched controls randomly drawn by population registries. Residential proximity to 5333 oil and gas production sites at the time of diagnosis was calculated. Unconditional logistic regression models were used to estimate the association between living within 1 km of any exposure site and developing a hematologic malignancy. Models were adjusted for matching variables sex, age group, district, and year of diagnosis as well as for proximity to main streets and to agricultural land. Results We found no association between the development of hematologic malignancies and the proximity to all oil and gas production sites (odds ratio: 0.97;95% confidence interval: 0.85, 1.11). Focusing on gas production sites increased the odds of developing hematologic cancer (odds ratio: 1.19;95% confidence interval: 0.97, 1.45). In stratified analyses, associations were stronger in women and for acute myeloblastic leukemia. We also found an association in the district where the initial cluster occurred. Conclusions Our results suggest that residential proximity to oil and gas production is not a risk factor for all hematologic malignancies in general. Sporadic and past exposures are the most likely scenarios for mechanisms involving oil and gas production, leading to increased risk for certain subtypes of cancer in certain populations
Erfolgreiche Prävention braucht eine geschlechtergerechte Ansprache
No full textEinleitung
Um die Bevölkerung zur Teilnahme an Präventionsmaßnahmen zu gewinnen, kommt es nicht nur auf einen geeignete Zugangsweg an, über den die Zielgruppe erreicht werden kann, sondern auch auf eine zielgruppengerechte Ansprache. Obwohl die ältere Bevölkerung als Zielgruppe erkannt wird und sich mittlerweile vielfältige Ansätze auf Bundes- und Landesebene sowie im kommunalen Bereich etabliert haben, sind die Ausrichtung der Präventionsprogramme und die Ansprache häufig nicht zielgruppenspezifisch. Innerhalb der älteren Bevölkerungsgruppe wird selten nach Lebens- und Problemlagen differenziert und die Kategorie Geschlecht wird dabei kaum berücksichtigt.</jats:p
Quantitative analysis of chloroplast protein targeting
No full textThis thesis presents the first use of the Partition of Unity Method in quantifying
the spatio-temporal dynamics of a fluorescent protein targeted to
the chloroplast twin-arginine translocation pathway.
The fluorescence loss in photobleaching technique is applied in a modified
fashion to the measurement of substrate mobilities in the chloroplast
stroma. Our in vivo results address the two suggested protein targeting
mechanisms of membrane-binding before lateral movement to the translocon
and direct binding to the translocon.
A high performance computing C/C++ implementation of the Partition
of Unity Method is used to perform simulations of fluoresence loss
in photobleaching and allow a compelling comparison to photobleaching
data series. The implementation is both mesh-free and particle-less
