1,988 research outputs found

    Elastic-DF: Scaling Performance of DNN Inference in FPGA Clouds through Automatic Partitioning

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    Customized compute acceleration in the datacenter is key to the wider roll-out of applications based on deep neural network (DNN) inference. In this article, we investigate how to maximize the performance and scalability of field-programmable gate array (FPGA)-based pipeline dataflow DNN inference accelerators (DFAs) automatically on computing infrastructures consisting of multi-die, network-connected FPGAs. We present Elastic-DF, a novel resource partitioning tool and associated FPGA runtime infrastructure that integrates with the DNN compiler FINN. Elastic-DF allocates FPGA resources to DNN layers and layers to individual FPGA dies to maximize the total performance of the multi-FPGA system. In the resulting Elastic-DF mapping, the accelerator may be instantiated multiple times, and each instance may be segmented across multiple FPGAs transparently, whereby the segments communicate peer-to-peer through 100 Gbps Ethernet FPGA infrastructure, without host involvement. When applied to ResNet-50, Elastic-DF provides a 44% latency decrease on Alveo U280. For MobileNetV1 on Alveo U200 and U280, Elastic-DF enables a 78% throughput increase, eliminating the performance difference between these cards and the larger Alveo U250. Elastic-DF also increases operating frequency in all our experiments, on average by over 20%. Elastic-DF therefore increases performance portability between different sizes of FPGA and increases the critical throughput per cost metric of datacenter inference. Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Computer Engineerin

    Anti-nociceptive and anti-inflammatory activities of crude root extract and solvent fractions of Cucumis ficifolius in mice model

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    Desalegn Getnet Demsie,1,2 Ebrahim M Yimer,1 Abera Hadgu Berhe,1 Birhanetensay Masresha Altaye,3 Derbew Fikadu Berhe11Department of Pharmacology and Toxicology, College of Health Sciences, Mekelle University, Mekelle, Ethiopia; 2Department of Pharmacy, College of Medicine and Health Sciences, Adigrat University, Adigrat, Ethiopia; 3Department of Pharmacy, College of Medicine, Debre Berhan University, Debre Berhan, EthiopiaBackground: Societies in developing countries use traditional medicine as alternatives for management of pain and inflammation. The plant Cucumis ficifolius has been used in Ethiopia to treat many ailments including inflammation and pain. The objective of this study was to evaluate the antinociceptive and anti-inflammatory activities of the crude root extract and solvent fractions of C. ficifolius.Methods: The analgesic activity of crude extract and solvent fractions of C. ficifolius was evaluated with acetic acid-induced writhing, hot plate, and formalin-induced paw licking tests. The anti-inflammatory effect of crude methanolic root extract and solvent fractions of C. ficifolius was evaluated using carrageenan-induced paw edema. The crude extract was given at 200, 400 and 800 mg/kg. Butanol and aqueous fractions were given at 100 and 200 mg/kg doses. The negative control groups were treated with distilled water (10 mL/kg). Standard drugs used wereacetylsalicylic acid(ASA) in acetic acid, formalin tests and carrageenan-induced paw edema and morphine (20 mg/kg) in hot plate test.Results: The crude extract, at its maximum dose, produced comparable analgesic activity (72.5%) to ASA in acetic acid writhing test. In the hot plate test, both the crude extract and solvent fractions exhibited a significant prolongation of nociception reaction time. Formalin test result indicated a significant reduction of mean lick time with maximal protection of 64% (early phase) and 83% (late phase). Aqueous and butanol fractions showed good analgesic activity in the three models. Inflammation was decreased by 69% with butanol (200 mg/kg); 71% (800 mg/kg) of crude extract and by 41% and 56% with the use of aqueous fraction at 100 and 200 mg/kg, respectively (p<0.001).Conclusion: The present study indicates that the crude methanolic root extract, as well as butanol and aqueous solvent fractions, showed anti-nociceptive and anti-inflammatory activities.Keywords: hot plate test, writhing test, paw edema, formalin test, carrageenan, 80% methano

    Hydrodynamical turbulence by fractal fourier decimation

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    We present a systematic numerical investigation of high-resolution 3D isotropic and homogeneous turbulence resolved on a decimated set of Fourier modes. Fractal decimation acts to decrease the effective dimensionality of the flow by allowing triadic interactions only in a set of Fourier modes N(k) proportional to k^DF for large k. While keeping the symmetries of the original 3D Navier-Stokes equations unchanged, a dramatic change in small-scale statistics is detected at decreasing the fractal dimension DF . Already at fractal dimension DF = 2.8, a global self-similar behaviour is observed in the inertial range of scales, the consequence of such transition are the restoration of the scaling symmetry and vorticity distribution that becomes close to Gaussian. We relate the results to the different roles of local vs non-local interactions in the energy transfer range

    'Response by the author, Daniel F. Vukovich.'

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    Response by the author (Vukovich) to a review of Illiberal China (my 2019 monograph

    DF AND HF LASER SPECTRA

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    1^{1}W. B. Roh and K. Narahari Rao, J. Mol. Spectrosc. 49, 317 (1974).""Author Institution: Department of Physics, The Ohio State University; Department of Electrical Engineering, The Ohio State UniversityA pulsed laser was used as a source to study DF and HF infrared laser spectra with a grating spectrometer. The rotational structure observed for the 1-0, 2-1, and 3-2 bands of DF, and the 1-0 and 2-1 bands of HF has been measured by following a procedure similar to that used for the CO laser spectra.1spectra.^{1} Molecular constants derived by combining these laser measurements with other available data will be presented

    OPTOACOUSTIC MEASUREMENT OF DF LASER ABSORPTION BY METHANE

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    Author Institution:An optoacoustic system has been constructed for measurement of absorption of DF laser radiation. Absorption by methane in Argon and Nitrogen has been measured at 15 DF laser lines in the 3.6 – 4.0 μm\mu m region. Construction and calibration of the spectrophone will be discussed

    Comparison of system architecture and converter topology for a solar powered electric vehicle charging station

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    Accepted Author ManuscriptOld - EWI-ESE-DC&S DC systems & StoragePhotovoltaic Materials and Device

    Simulation of a surface-transverse wave (STW) biosensor for DF-1 cells

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    A 250 MHz Surface-Transverse Wave (STW) resonator is employed as a sensor element for the detection of DF-1 cells. STW belongs to the shear-horizontal acoustic plate modes (SH-APM) waves’ family where it has attracted plenty considerable interest. STWs are horizontally polarized shear waves which are generated and detected by the interdigital transducers (IDTs) similar to surface-acoustic wave (SAW) resonators [1]. Detection of chemical and biological agents in aqueous solutions is a difficult problem, especially when the detection technique has to be sensitive, power-efficient and very handy. Acoustic plate mode is a mode of vibration where particle motion is parallel to the surface. This makes it possible to produce a sensitive sensor capable of operating in fluids [2]. This paper presents the biosensor prototype utilizing STW resonator

    Period changes of two contact binaries: DF Hya and WZ And

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    33rd International Physics Congress of the Turkish-Physical-Society (TPS) -- SEP 06-10, 2017 -- Bodrum, TURKEYOrbital period variations of two contact binaries DF Hya and WZ And are analyzed with the least-squares method by using all available minima times. It is shown that the period variations of these systems are due mainly to the LightTime Effect (LITE) due originates from gravitational influence of a third body. New LITE elements such as, orbital periods and minimum masses of possibility third bodies are given.Turkish Phys So

    Delivery of bioactive molecules to the mitochondrial genome using a membrane-fusing, liposome-based carrier, DF-MITO-Porter.

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    Mitochondrial dysfunction has been implicated in a variety of human diseases. It is now well accepted that mutations and defects in the mitochondrial genome form the basis of these diseases. Therefore, mitochondrial gene therapy and diagnosis would be expected to have great medical benefits. To achieve such a strategy, it will be necessary to deliver therapeutic agents into mitochondria in living cells. We report here on an approach to accomplish this via the use of a Dual Function (DF)-MITO-Porter, aimed at the mitochondrial genome, so-called mitochondrial DNA (mtDNA). The DF-MITO-Porter, a nano carrier for mitochondrial delivery, has the ability to penetrate the endosomal and mitochondrial membranes via step-wise membrane fusion. We first constructed a DF-MITO-Porter encapsulating DNase I protein as a bioactive cargo. It was expected that mtDNA would be digested, when the DNase I was delivered to the mitochondria. We observed the intracellular trafficking of the carriers, and then measured mitochondrial activity and mtDNA-levels after the delivery of DNase I by the DF-MITO-Porter. The findings confirm that the DF-MITO-Porter effectively delivered the DNase I into the mitochondria, and provides a demonstration of its potential use in therapies that are selective for the mitochondrial genome
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