1,720,960 research outputs found

    Biaxial Testing of EPDM Rubbers for Automotive Applications Using a Uniaxial Testing Machine

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    The FE-based structural design of components made of rubber materials requires an experimental characterization to calibrate a proper hyperelastic material model. A strain energy density (SED) parameter is typically adopted to describe the hyperelastic behavior of isotropic rubbers. This can be written as a function of the strain tensors, the strain invariants or the stretch ratios and proper material parameters. The latter must be calibrated on experimental data generated by testing rubber materials under different loading conditions, typically two among uniaxial tension, pure shear and biaxial tension. In this context, the mechanical behavior of Ethylene-Propylene-Diene Monomer (EPDM) rubbers, both in the dense and expanded configurations, which are typically employed to manufacture automotive seals, has been investigated. First, uniaxial tension tests have been performed. Afterwards, a new fixture has been developed to perform equi-biaxial tension tests using a uniaxial testing machine. The fixture has been adopted to test EPDM cruciform specimens under equi-biaxial tension loading. Finally, both uniaxial and equi-biaxial data have been employed to fit a Mooney-Rivlin material model for each tested EPDM rubber, which has been validated by comparing the results of FE simulations with the experimental ones

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Experimental tests and fatigue strength assessment of a scotch yoke valve actuator

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    Aim of this work is the fatigue assessment of a main component of a valve actuator used for oil & gas, power and chemical industries, in order to comply with its heavy-duty applications. To do this, full-scale valve actuator assemblies made of S355J2 steel have been fatigue tested under nominal axial loading. All specimens have been tested under stress-relieved conditions by adopting a nominal load ratio R=-1. After experimental tests, the fatigue crack paths have been analysed by means of liquid penetrant inspections. The fatigue strength class of the considered yoke has been determined by statistically re-analysing the experimental results, expressed in terms of range of the nominal applied load, and it has been compared with the design condition required by the relevant European Standard, EN 15714-3/4. Finally, two methodologies for fatigue strength assessment of the considered scotch yokes have been proposed, which are based on experimental fatigue data derived from smooth or sharp V-notched specimens, respectively, made of the same yoke material. The assessment capability of the proposed methodologies has been evaluated and discussed by comparing theoretical estimations with the experimental fatigue results of the scotch yokes

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Selection of suitable reference genes for gene expression studies in HMC3 cell line by quantitative real-time RT-PCR

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    Abstract Microglia represent the primary immune defense system within the central nervous system and play a role in the inflammatory processes occurring in numerous disorders, such as Parkinson’s disease (PD). PD onset and progression are associated with factors considered possible causes of neuroinflammation, i.e. genetic mutations. In vitro models of microglial cells were established to identify specific molecular targets in PD through the analysis of gene expression data. Recently, the Human Microglial Clone 3 cell line (HMC3) has been characterized and a new human microglia model has emerged. Here we perform RT-qPCR analyses to evaluate the expression of ten reference genes in HMC3, untreated or stimulated to a pro-inflammatory status. The comparative ∆CT method, BestKeeper, Normfinder, geNorm and RefFinder algorithms were used to assess the stability of the candidate genes. The results showed that the most suitable internal controls are HPRT1, RPS18 and B2M genes. In addition, the most stable and unstable reference genes were used to normalize the expression of a gene of interest in HMC3, resulting in a difference in the statistical significance in cells treated with Rotenone. This is the first reference gene validation study in HMC3 cell line in pro-inflammatory status and can contribute to more reliable gene expression analysis in the field of neurodegenerative and neuroinflammatory research

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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