196,606 research outputs found
Personal Papers (MS 80-0002)
No full textLetter from D. M. Stahl of the Henri Bendel company to Jeane Kempner refunding her $90
Personal Papers (MS 80-0002)
No full textLetter from Henri Bendel to Henrietta Leonora Blum Kempner discussing a refund to her charge account in the amount of $49.95
Lernen von den Kleinen: Neues und Altes zu Mobile Learning
No full textSeit über zehn Jahren ist Mobile Learning ein Thema. Heute gibt es etliche Anwendungen für Smartphones und Tablets. Und Handys und Smartphones sind zur Schnittstelle geworden, die Realität und Virtualität verbindet. M-Learning setzt sich in Hochschulen und Unternehmen durch und bietet Möglichkeiten für Privatpersonen. Mobile Learning gehört, so Oliver Bendel in seinem Artikel, der Gedanken aus einem zehn Jahre alten Beitrag zum Thema aufnimmt, die Zukunft. Es werde uns aber gut tun, immer wieder das Gadget aus der Hand zu legen und die Gedanken schweifen zu lassen. Auch und vor allem, wenn wir unterwegs sind
NMDA receptors in neurodegeneration : studies on NMDA receptor subunit expression preceding ischemia-induced delayed nerve cell death
No full textNMDA receptors are glutamate-gated ion channels that are permeable to Ca2+. NMDA receptors are tetramers formed by a combination of subunits. In the present thesis, we describe the novel NR3B subunit that we cloned in mouse and human. NR3B was found to be expressed in the adult rat and human central nervous system (CNS). Also, human NR3A was cloned and it's expression in the adult human CNS was investigated. In addition, we identified, cloned, and characterized tissue expression of a previously unknown gene, which we named membralin because it contains several transmembrane regions. Notably, the genes that encode membralin and NR3B were found to be oriented in an anti-parallel fashion, both in the mouse and the human genomes.Excessive Ca2+ influx through NMDA receptors is a major mechanism for neurodegeneration following stroke and brain trauma. To better understand the mechanisms behind NMDA-dependent neurodegeneration, we used, developed, and characterized three injury models in the rat: crush injury in entorhinal hippocampal slices, global ischemia, and subarachnoid hemorrhage. Temporal and regional patterns of cell death were evaluated in these models with focus on delayed cell death.Crush-injury in slices induced two phases of cell death, including an early phase that peaked within a day after injury and a delayed phase that appeared at 4 DAI. Treatment with the NMDA receptor antagonist MK-801 (30 ìM) for 2 h at the time of the injury prevented the delayed but not the early phase of cell death. Also, we analyzed the inflammatory response at various time-points after crush-injury. Two complement components: C1q and C5b-9 and the complement inhibitor clusterin were dramatically up-regulated after injury. These studies indicate that delayed cell death in this model is dependent on NMDA receptor activation and that the complement cascade can be activated in vitro, without the influence of exogenous blood products and cells.A new reproducible global ischemia model was developed. Eleven min of global ischemia induced delayed cell death of CA1 neurons in the hippocampus, as shown by Fluoro-Jade, cresyl-violet and NeuN staining. The death of CA1 neurons was correlated to deficiencies in learning and memory, as analyzed using the Morris water maze and a novel water T-maze. At 90 days after ischemia, new CA1 neurons had formed, associated with a marked recovery in learning and memory. At 250 days after ischemia, the ischemia-induced new neurons were found to degenerate in association with the appearance of Ca2+ deposits, but without significant attenuation of learning and memory performance.In a model of subarachoidal hemorrhage, we demonstrated delayed nerve cell death in CA1 and CA3, and found the extent of cell death to relate to the severity of the transient ischemia. We found that the delayed nerve cell death in both the global ischemia model and in the subarachnoid hemorrhage model was preceded by down regulation of specific NMDA receptor subunits, with somewhat different profiles in the two models. Also the total number of NMDA receptors was found to be decreased using [3H]MK-801 autoradiography.These studies may give a better understanding of the role of NMDA receptors in delayed neurodegeneration, and provide a basis for the development of new neuroprotective treatments.List of scientific papersI. Andersson O, Stenqvist A, Attersand A, von Euler G (2001). "Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B." Genomics 78(3): 178-84 https://pubmed.ncbi.nlm.nih.gov/11735224II. Bendel O, Meijer B, Hurd Y, von Euler G (2005). "Cloning and expression of the human NMDA receptor subunit NR3B in the adult human hippocampus." Neurosci Lett 377(1): 31-6. Epub 2004 Dec 15 https://pubmed.ncbi.nlm.nih.gov/15722182III. Andersson O, von Euler G (2002). "Characterization and expression of the gene encoding membralin, an evolutionary conserved protein expressed in the central nervous system." Brain Res Gene Expr Patterns 1(3-4): 205-12 https://pubmed.ncbi.nlm.nih.gov/12638133IV. Bendel O, Langmoen IA, von Euler G (2004). "Crush injury induces NMDA-receptor-dependent delayed nerve cell death in rat entorhinal-hippocampal slice cultures." Brain Res 1025(1-2): 35-42 https://pubmed.ncbi.nlm.nih.gov/15464742V. Bellander BM, Bendel O, Von Euler G, Ohlsson M, Svensson M (2004). "Activation of microglial cells and complement following traumatic injury in rat entorhinal-hippocampal slice cultures." J Neurotrauma 21(5): 605-15 https://pubmed.ncbi.nlm.nih.gov/15165368VI. Bendel O, Alkass K, Bueters T, von Euler M, von Euler G (2005). "Reproducible loss of CA1 neurons following carotid artery occlusion combined with halothane-induced hypotension." Brain Res 1033(2): 135-42 https://pubmed.ncbi.nlm.nih.gov/15694917VII. Bendel O, Bueters T, von Euler M, Ove Ogren S, Sandin J, von Euler G (2005). "Reappearance of hippocampal CA1 neurons after ischemia is associated with recovery of learning and memory." J Cereb Blood Flow Metab 25(12): 1586-95 https://pubmed.ncbi.nlm.nih.gov/15917746VIII. von Euler M, Bendel O, Bueters T, Sandin J, von Euler G (2006). "Profound but transient deficits in learning and memory after global ischemia using a novel water maze test." Behav Brain Res 166(2): 204-10. Epub 2005 Sep 12 https://pubmed.ncbi.nlm.nih.gov/16159675IX. Bueters T, von Euler M, Bendel O, von Euler G (2007). "Degeneration of newly formed CA1 neurons following global ischemia in the rat." Exp Neurol Sep 15: Epub ahead of print https://pubmed.ncbi.nlm.nih.gov/17950278X. Bueters, T (2007). "Changes in NMDA receptor subunit expression precedes degeneration of CA1 neuron following transient global ischemia in the rat." (Manuscript)XI. Bendel O, Prunell G, Stenqvist A, Mathiesen T, Holmin S, Svendgaard NA, Euler G (2005). "Experimental subarachnoid hemorrhage induces changes in the levels of hippocampal NMDA receptor subunit mRNA." Brain Res Mol Brain Res 137(1-2): 119-25. Epub 2005 Apr 7 https://pubmed.ncbi.nlm.nih.gov/15950769</p
Recommended from our members
Dallas Museum of Fashion Collection
No full textHat of red straw. The low, flat-top crown slopes to base, swelling out to form a very narrow brim. The body of the hat is of a loose woven red straw overlaid with strips of woven red straw radiating from the top center of the crown. At the front of the hat is a dark red velvet bow. The interior of the hat is unlined, but the strips of straw continue under the brim, forming a self-lining. Around inside of crown at base is an inner hatband of dark red grosgrain ribbon. Attached to the inner hatband is a black elasticized cord to secure hat to wearer's head. Beneath brim towards back extend small red velvet covered metal(?) loops to help secure hat to wearer's head.
Designer's label sewn inside crown: "Gilbert Orcel / Paris / Made in France.
Retailer's label sewn to inner hatband: "Henri Bendel / New York
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
Jugendliche zum Erzählen existenzieller Ereignisse anregen: Narrativ orientierte Gesprächseinstiege in psychotherapeutisch geführten Erzählinterviews
No full textKnerich H, Haagen M, Kohl J. Jugendliche zum Erzählen existenzieller Ereignisse anregen: Narrativ orientierte Gesprächseinstiege in psychotherapeutisch geführten Erzählinterviews. In: Bendel Larcher S, Pick I, eds. Good practice in der institutionellen Kommunikation. Von der Deskription zur Bewertung in der Angewandten Gesprächsforschung. De Gruyter; 2023: 175-198
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Dr. Glendon Swarthout
No full textHosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness
- …
