70 research outputs found
The End of the Risk-Free Rate: Investing When Structural Forces Change Government Debt
No full textBen Emons explains why government debt is no longer "risk free"--and how you can seek alternatives in order to invest your money accordingly
A timely alert to the fundamental changes taking place in today\u27s global economic and financial systems. The book discusses why there is no longer a true risk free rate, how this will impact risk premiums, financial and real asset valuations, what could be the future alternatives to the risk free rate and what to look for when investing
The Financial Domino Effect: How to Profit Now in the Volatile Global Economy
No full textPredict and profit from the chain reactions of market turmoil “If you care about the inner dynamics and investors’ reactions to the emerging new financial world that will increasingly consist of ‘path-dependent, multimodal, fat-tailed outcomes,’ Ben Emons’s new book is a must-read. In a coherent and clear framework, Ben shows how falling dominoes in a world of fast markets and uniquely new possibili¬ties creates a market landscape we might never have prepared for.” —Vineer Bhansali, Managing Director, Portfolio Manager, PIMCO“At some point after getting your financial life in order, you may well have money to invest
Caspase inhibitors affect the kinetics and dimensions of tracheary elements in xylogenic Zinnia (<it>Zinnia elegans</it>) cell cultures
No full textAbstract Background The xylem vascular system is composed of fused dead, hollow cells called tracheary elements (TEs) that originate through trans-differentiation of root and shoot cambium cells. TEs undergo autolysis as they differentiate and mature. The final stage of the formation of TEs in plants is the death of the involved cells, a process showing some similarities to programmed cell death (PCD) in animal systems. Plant proteases with functional similarity to proteases involved in mammalian apoptotic cell death (caspases) are suggested as an integral part of the core mechanism of most PCD responses in plants, but participation of plant caspase-like proteases in TE PCD has not yet been documented. Results Confocal microscopic images revealed the consecutive stages of TE formation in Zinnia cells during trans-differentiation. Application of the caspase inhibitors Z-Asp-CH2-DCB, Ac-YVAD-CMK and Ac-DEVD-CHO affected the kinetics of formation and the dimensions of the TEs resulting in a significant delay of TE formation, production of larger TEs and in elimination of the 'two-wave' pattern of TE production. DNA breakdown and appearance of TUNEL-positive nuclei was observed in xylogenic cultures and this was suppressed in the presence of caspase inhibitors. Conclusions To the best of our knowledge this is the first report showing that caspase inhibitors can modulate the process of trans-differentiation in Zinnia xylogenic cell cultures. As caspase inhibitors are closely associated with cell death inhibition in a variety of plant systems, this suggests that the altered TE formation results from suppression of PCD. The findings presented here are a first step towards the use of appropriate PCD signalling modulators or related molecular genetic strategies to improve the hydraulic properties of xylem vessels in favour of the quality and shelf life of plants or plant parts.</p
Accuracy Versus Falsification Costs: The Optimal Amount of Evidence under Different Procedures
No full textAn arbiter can decide a case on the basis of his priors or he can ask for further evidence from the two parties to the conflict. The parties may misrepresent evidence in their favor at a cost. The arbiter is concerned about accuracy and low procedural costs. When both parties testify, each of them distorts the evidence less than when they testify alone. When the fixed cost of testifying is low, the arbiter hears both, for intermediate values one, and for high values no party at all. The arbiter's ability to remain uninformed as well as sequential testifying makes it more likely that the arbiter requires evidence. (JEL D82, K41, K42) The Author 2007. Published by Oxford University Press on behalf of Yale University. All rights reserved. For permissions, please email: [email protected], Oxford University Press.
The end of the risk free rate: investing when structural forces change government debt
No full textx, 242 p. ; 24cm
The financial domino effect : how to profit now in the volatile global economy
No full textix, 244 p. ; 24 cm
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