480 research outputs found
Cloud hosted business-data driven BI platforms
No full textBusiness Intelligence in Platform as a Service (PaaS) for information analysis is increasingly being considered for its applications in the enterprises because of its advantages. It is widely used for Data Analysis, Customer Churn Prediction, etc. However, the challenges that the traditional BI platform faces includes the tremendous volume of data, high time and space complexity of algorithms and the incompatibility in the Integration to the BI tools. Thus instead of having traditional Data Warehouses for storage which require high maintenance and storages, companies are moving towards more efficient cloud based storages
Assessment and Prevention Of Falls In Elderly: Nurses’ Role
No full textFalls in elderlies has been a major concern in geriatric care. One out of three elderlies have
been falling every year and the many more elderlies are constantly at risk of falls. These falls
lead to serious injuries like hip fractures and build sense of fear in elderlies, which limit their
activities and degrade their quality of life.
There has been seen a huge need to enhance the skill and knowledge of the present and future
nurses to ensure that they are professionally and personally capable to identify the risk factors
and plan prevention strategies accordingly.
Literature review has been used in this thesis to find out the possible assessment methods to
assess the risk factors of falls in elderly, the vulnerable groups of elderlies who have higher
chances of falling. In addition, the possible falls prevention strategies have been studied and
laid out in this thesis.
A total of 11 relevant articles were obtained from a reliable database search.
The contents of the thesis have been categorized into distinct assessment and prevention
headings for ease of reading and finding required information. In the conclusion end, the author has presented his own ideas and discussed the additional need for safety of elderlies
Publisher Correction:Dysregulation of ghrelin in diabetes impairs the vascular reparative response to hindlimb ischemia in a mouse model; clinical relevance to peripheral artery disease (Scientific Reports, (2020), 10, 1, (13651), 10.1038/s41598-020-70391-6)
No full textIn the original version of this Article, Rajesh Katare and Daryl O. Schwenke were omitted as equally contributing authors. In addition, Rajesh Katare was omitted as a corresponding author. Correspondence and requests for materials should also be addressed to [email protected]. These errors have now been corrected in the HTML and PDF versions of the Article.</p
Substitution Kinetics of [Fe(PDT/PPDT)n(phen)m]2+ (n ≠ m; n,m = 1,2) with 2,2′-Bipyridine, 1,10-Phenanthroline, and 2,2′,6,2″-Terpyridine
No full textThe triazines 3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine (PDT), 3-(4-phenyl-2-pyridyl)-5,6-diphenyl-1,2,4-triazine (PPDT), and 1,10-phenanthroline (phen) were coordinated to the Fe2+ ion to form urn:x-wiley:05388066:media:kin21066:kin21066-math-0001 (1), urn:x-wiley:05388066:media:kin21066:kin21066-math-0002 (2), urn:x-wiley:05388066:media:kin21066:kin21066-math-0003, (3) and urn:x-wiley:05388066:media:kin21066:kin21066-math-0004 (4). The complexes were synthesized and characterized by mass spectroscopy and elemental analysis. The rate of substitution of these complexes by 2,2′-bipyridine (bpy), 1,10-phenanthroline (phen), and 2,2′,6,2″-terpyridine (terpy) was studied in a sodium acetate–acetic acid buffers over the range 3.6–5.6 at 25, 35, and 45°C under pseudo–first-order conditions. The reactions are first order with respect to the concentration of the complexes. The reaction rates increase with increasing [bpy/phen/terpy] and pH, whereas ionic strength has no influence on the rate of reaction. Plots of kobs versus [bpy/phen/terpy] and 1/[H+] are linear with positive slopes and significant y-intercepts. This indicates that the reactions proceed by both dissociative as well as associative pathways for which the associative pathway predominates the substitution kinetics. Observed temperature-depended rate constants at the three temperatures at which substitution reactions were studied together with the protonation constants of the substituting ligands (phen, bpy, terpy) were used to evaluate the specific rate constants (k1 and k2) and thermodynamic parameters (Ea, ΔH#, ΔS#, and ΔG#). The reactivity order of the four complexes depends on the phenyl groups present on the triazine (PDT/PPDT) molecule. The π-electrons on phenyl rings stabilizes the charge on the metal center by inductive donation of electrons toward the metal center resulting in a decrease in reactivity of the complex, and the order is 1 terpy > bpy. Higher rate constants, low Ea values, and more negative entropy of activation (−ΔS#) values were observed for the associative path, revealing that substitution reactions at the octahedral iron(II) complexes by bpy, phen, and terpy occur predominantly by the associative mechanism. Density functional theory calculations support the interpretations
Heterogeneous networking testbeds integration and wireless network virtualization
No full textNetworking research has grown immensely over the past few years. This has urged the need for a heterogeneous networking research infrastructure, to experiment with the interaction and integration of different types of networks. This requirement led to the Global Environment for Network Innovations (GENI) effort, supported by NSF, which aims at creating a global infrastructure for conducting networking experiments across diverse substrates such as
wired, wireless, sensor and cellular networks. In this work, we discuss challenges involved in federating two diverse testbeds - PlanetLab and ORBIT and present a model for building a united
infrastructure for the models. PlanetLab is a global research wired network that supports the development of new network services. ORBIT
is a laboratory-based wireless network emulator for 802.11 testing.
An integrated wired-wireless testbed will increase the scalability of experimentation. Proof-of-concept experiments are also presented reinforcing the usefulness of the model in terms of facilitating experiments over the integrated infrastructure.
Such an integrated infrastructure poses a requirement of support for wireless network virtualization - supporting multiple concurrent
wireless experiments. Unlike wired networks, wireless networks present unique challenges making the task of wireless virtualization
a difficult problem. The critical problem of simultaneous experimentation in networks involving the wireless medium are identified and approaches towards it are discussed. We evaluate and compare two approaches towards wireless virtualization - SDMA (Space Division Channel Multiplexing) and VAP (Virtual AP Channel Multiplexing) suitable for supporting long running experiments. In this study conducted on ORBIT we quantify the difference in
performance and interference when using wireless virtualization and suggest measures to mitigate the same. The feasibilty study will serve as the first step towards ORBIT virtualization.M.S.Includes bibliographical references (p. 63-65)
A Systematic Review on Author Identification Methods
No full textAuthor Identification is a technique for identifying author of anonymous text. It has near about 130 year's long history, started with the work by Mendenhall 1987. Applications of Author identification include plagiarism detection, detecting anonymous author, in forensics and so on. In this paper the authors outline features used for Author identification like vocabulary, syntactic and others. Researchers worked on various methods for Author identification they also outline this paper on types of Author Identification methods that include 1. Profile-based Approaches which includes Probabilistic Models, Compression Models, Common n-Grams (CNG) approach, 2. Instance-based Approaches which includes Vector Space Models, Similarity-based Models, Meta-learning Models and 3. Hybrid Approaches. At the end the authors conclude this paper with observations and future scope.</p
Rajesh Research data
No full textFirst author are the data procurer from his Ph.D. research.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV
Evidence for a role of nitric oxide in iron homeostasis in plants
No full textNitric oxide (NO), once regarded as a poisonous air pollutant, is now understood as a regulatory molecule essential for several biological functions in plants. In this review, we summarize NO generation in different plant organs and cellular compartments, and also discuss the role of NO in iron (Fe) homeostasis, particularly in Fe-deficient plants. Fe is one of the most limiting essential nutrient elements for plants. Plants often exhibit Fe deficiency symptoms despite sufficient tissue Fe concentrations. NO appears to not only up-regulate Fe uptake mechanisms but also makes Fe more bioavailable for metabolic functions. NO forms complexes with Fe, which can then be delivered into target cells/tissues. NO generated in plants can alleviate oxidative stress by regulating antioxidant defense processes, probably by improving functional Fe status and by inducing post-translational modifications in the enzymes/proteins involved in antioxidant defense responses. It is hypothesized that NO acts in cooperation with transcription factors such as bHLHs, FIT, and IRO to regulate the expression of enzymes and proteins essential for Fe homeostasis. However, further investigations are needed to disentangle the interaction of NO with intracellular target molecules that leads to enhanced internal Fe availability in plants.RKT is grateful to Department of Science and Technology-Science and Engineering Research Board (DST-SERB) New Delhi, for a Teachers Associateship for Research Excellence (TAR/2019/000064).Tewari, RK (corresponding author), Univ Lucknow, Dept Bot, Lucknow 226007, Uttar Pradesh, India.
[email protected]
Heterodinuclear Ru–Pt Complexes Bridged with 2,3-Bis(pyridyl)pyrazinyl Ligands: Studies on Kinetics, Deoxyribonucleic Acid/Bovine Serum Albumin Binding and Cleavage, In Vitro Cytotoxicity, and In Vivo Toxicity on Zebrafish Embryo Activities
No full textDi- and poly-homo/heteronuclear complexes have great potential as anticancer drugs. Here, we report their reactivity, deoxyribonucleic acid (DNA)/bovine serum albumin (BSA) binding and cleavage interactions, in vitro cytotoxicity, and in vivo zebrafish embryo toxicity of [(phen)2Ru(μ-L)PtCl2]2+ (phen = 1,10-phenanthroline and L = 2,3-bis(2-pyridyl)pyrazine, bpp, C1; 2,3-bis(2-pyridyl)quinoxaline, bpq, C2ial; 2,3-bis(2-pyridyl)benzo[g]quinoxaline, bbq, C3) anticancer prodrugs. The substitution reactivity increases from C1 to C3 owing to an increase in the π-conjugation on the bridging chelate which facilitates π-back bonding. As a result, the electrophilicity index on the C3 complex increases than that on the complex C2 followed by C1 which leads to higher rates of substitution and thus the reactivity order follows C1 9 μM); furthermore, the selectivity index and SI values were higher (>3). Complex C3 showed the highest cytotoxicity with IC50 = 3.1 μM and SI value (5.55) against MCF7 cell lines and these values were comparable to those of the cisplatin (IC50 and SI values are 5.0 μM and 4.02, respectively). In vivo toxicological assessments on zebrafish embryos revealed that all the Ru–Pt complexes (CI/2/3) have poor embryo acute toxic effects over 96 h postfertilization, hpf with LC50 > 65.2 μM. The complex C3 has shown the lowest embryo toxicity (LC50 = 148.8 μM), which is comparable to that of commercial cisplatin (LC50 = 181.1 μM). Based on the cytotoxicity results, complexes C2 and C3 could be considered for further development as chemotherapeutic agents against MCF breast cancer cells
Base hydrolysis of tris(3-(2-pyridyl)-5,6-bis(4-phenyl sulphonic acid)-1,2,4-triazine)iron(II) in aqueous, SDS and CTAB media: kinetic and mechanistic study
No full text- …
