296 research outputs found
Will Marieke Hardy’s twitter case change Australian law for ever?
No full text.
Twitter is being sued for defamation by a Melbourne man who was wrongly identified as the author of a “hate blog” directed at writer and TV personality, Marieke Hardy.
Hardy posted a tweet last year to “name and shame” Joshua Meggitt, the Melbourne man she incorrectly identified as the blog’s author, leading Meggitt to sue Twitter for defamation.
While Meggitt and Hardy have already apparently reached a (confidential) legal settlement, the broader issue of Twitter’s moral culpability and legal responsibility for allegedly defamatory tweets has now been brought sharply into focus.
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Photo: Flickr / Christophe Verdie
AUTHOR CORRECTION - ERS International Congress 2019:highlights from Best Abstract awardees
No full textLorna E. Latimer, Marieke Duiverman, Mahmoud I. Abdel-Aziz, Gulser Caliskan, Sara M. Mensink-Bout, Alberto Mendoza-Valderrey, Aurelien Justet, Junichi Omura, Karthi Srikanthan, Jana De Brandt. Breathe 2019; 15: e143–e149. This article from the December 2019 issue of Breathe was published with an error in the name of one of the authors. The corrected author list is shown above. The article has been corrected and republished online.</p
Style and context of old Greek Job /
No full textIn 'Style and Context of Old Greek Job', Marieke Dhont offers a new understanding of the linguistic and stylistic diversity in the Septuagint corpus. To this end, the author innovatively uses Polysystem Theory, which has been developed in the field of modern literary studies. After discussing the appropriateness of a systemic approach to understanding Jewish-Greek literature, the author reflects on the Jewishness of Greek-language texts. Dhont then presents a thorough literary analysis of the Old Greek version of the book of Job. On this basis, she explains the literary dynamics that produced the translation of Old Greek Job and its position within the development of a Jewish-Greek literary tradition.Includes bibliographical references and index.In 'Style and Context of Old Greek Job', Marieke Dhont offers a new understanding of the linguistic and stylistic diversity in the Septuagint corpus. To this end, the author innovatively uses Polysystem Theory, which has been developed in the field of modern literary studies. After discussing the appropriateness of a systemic approach to understanding Jewish-Greek literature, the author reflects on the Jewishness of Greek-language texts. Dhont then presents a thorough literary analysis of the Old Greek version of the book of Job. On this basis, she explains the literary dynamics that produced the translation of Old Greek Job and its position within the development of a Jewish-Greek literary tradition
Consumer Behavior and Culture: Consequences for Global Marketing and Advertising, 2/E.
No full textThe Second Edition of this popular text brings up-to-date Marieke de Mooij’s important analysis of the impact of culture on consumer behavior worldwide. The author shows how it is increasingly vital for marketing students-tomorrow’s marketing professionals-to understand the limits of consistent brand identities and universal advertising campaigns. Consumer behavior is not converging across countries, and therefore it is of even greater importance to understand, and be able to respond to, differences in behavior. This edition offers a new chapter, Chapter 7, on culture, communication, and media behavior that extends the prior edition’s discussion on communication theories and advertising styles to cover differences in media usage worldwide, particularly the use of the Internet
Generalizing Non-punctuality for Timed Temporal Logic with Freeze Quantifiers
No full textMetric Temporal Logic (MTL) and Timed Propositional Temporal Logic (TPTL) are prominent real-time extensions of Linear Temporal Logic (LTL). In general, the satisfiability checking problem for these extensions is undecidable when both the future U and the past S modalities are used. In a classical result, the satisfiability checking for MITL[U,S], a non-punctual fragment of MTL[U,S], is shown to be decidable with EXPSPACE complete complexity. Given that this notion of non-punctuality does not recover decidability in the case of TPTL[U,S], we propose a generalization of non-punctuality called non-adjacency for TPTL[U,S], and focus on its 1-variable fragment, 1-TPTL[U,S]. While non-adjacent 1-TPTL[U,S] appears to be a very small fragment, it is strictly more expressive than MITL. As our main result, we show that the satisfiability checking problem for non-adjacent 1-TPTL[U,S] is decidable with EXPSPACE complete complexity.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Team Manuel Mazo J
Addressing the barriers for delivery of liposomal nanoparticles to tumors
No full textThis study concerns the enhanced delivery of three types of fluorescently labelled liposomal nanoparticles to prostate cancer xenographs. Passive delivery of the liposomes was achieved by utilizing the enhanced permeability and retention effect within tumors, while active delivery was achieved by introducing microbubbles along with the liposomal nanoparticles and applying ultrasound locally to the tumor tissue. Cavitation of the microbubbles will induce stress on the blood vessel walls, which increases their permeability. Ultrasound can also cause local streaming of interstitial liquid and thereby increase penetration of nanoparticles into tumor tissue. In this study, four barriers to drug delivery was addressed by studying the aggregation behaviour of the NPs, their extravasation and distribution in tumor tissue with and without exposure to ultrasound and microbubbles, and their cellular uptake in vitro. Poly(ethylene glycol) is attached to all three types of liposomal nanoparticles to increase their stealth.
For all three formulations the fluorescence emission spectra were captured and assessed. Aggregation behaviour of the NPs when mixed with whole blood and serum was investigated by confocal microscopy. The research was concerned with animal experiments on mice (all animal experiments were performed by Ph.D. candidate Marieke Olsman). Tumor tissue samples from the animal experiments were imaged by confocal and multiphoton microscopy by the author, and image analysis was performed to evaluate the effect of ultrasound on the extravasation of nanoparticles and distance travelled from the blood vessel wall. In addition, in vitro cellular uptake of the three nanoparticles was investigated using flow cytometry, supported by confocal microscopy. The behaviour of the three liposomal nanoparticles when mixed with whole blood and serum was investigated by confocal microscopy.
Applying ultrasound was found to minimally increase extravasation of all three nanoparticles for both mechanical indices, with the exception of one low ultrasound intensity group. A large mean distance travelled from blood vessels was obtained when the extravasation was relatively high. A large degree of heterogeneity was seen between and within animals, making it challenging to evaluate whether the observed effects were truly due to ultrasound exposure. There was no clear aggregation behaviour of the nanoparticles observed when added to blood and serum, but more aggregates were observed in the stock solution of the standard nanoparticles, compared to the other two nanoparticles. The standard formulation of nanoparticles were taken up in cells much more frequently than the cleavable and non-cleavable formulations of nanoparticles. Removing of the poly(ethylene glycol) did not affect the cellular uptake in vitro
Addressing the barriers for delivery of liposomal nanoparticles to tumors
No full textThis study concerns the enhanced delivery of three types of fluorescently labelled liposomal nanoparticles to prostate cancer xenographs. Passive delivery of the liposomes was achieved by utilizing the enhanced permeability and retention effect within tumors, while active delivery was achieved by introducing microbubbles along with the liposomal nanoparticles and applying ultrasound locally to the tumor tissue. Cavitation of the microbubbles will induce stress on the blood vessel walls, which increases their permeability. Ultrasound can also cause local streaming of interstitial liquid and thereby increase penetration of nanoparticles into tumor tissue. In this study, four barriers to drug delivery was addressed by studying the aggregation behaviour of the NPs, their extravasation and distribution in tumor tissue with and without exposure to ultrasound and microbubbles, and their cellular uptake in vitro. Poly(ethylene glycol) is attached to all three types of liposomal nanoparticles to increase their stealth.
For all three formulations the fluorescence emission spectra were captured and assessed. Aggregation behaviour of the NPs when mixed with whole blood and serum was investigated by confocal microscopy. The research was concerned with animal experiments on mice (all animal experiments were performed by Ph.D. candidate Marieke Olsman). Tumor tissue samples from the animal experiments were imaged by confocal and multiphoton microscopy by the author, and image analysis was performed to evaluate the effect of ultrasound on the extravasation of nanoparticles and distance travelled from the blood vessel wall. In addition, in vitro cellular uptake of the three nanoparticles was investigated using flow cytometry, supported by confocal microscopy. The behaviour of the three liposomal nanoparticles when mixed with whole blood and serum was investigated by confocal microscopy.
Applying ultrasound was found to minimally increase extravasation of all three nanoparticles for both mechanical indices, with the exception of one low ultrasound intensity group. A large mean distance travelled from blood vessels was obtained when the extravasation was relatively high. A large degree of heterogeneity was seen between and within animals, making it challenging to evaluate whether the observed effects were truly due to ultrasound exposure. There was no clear aggregation behaviour of the nanoparticles observed when added to blood and serum, but more aggregates were observed in the stock solution of the standard nanoparticles, compared to the other two nanoparticles. The standard formulation of nanoparticles were taken up in cells much more frequently than the cleavable and non-cleavable formulations of nanoparticles. Removing of the poly(ethylene glycol) did not affect the cellular uptake in vitro
Design against loneliness: service design toollkit for social connectivity among the elderly
No full textLoneliness, as a social problem, has drawn wide attention of the academic and public. Moreover, loneliness among the elderly is significant. Up to 32% of adults older than age 55 report feeling lonely at any given time. Millions of euro have spent to identify the lonely elderly. With a great interest in social design, the author is intrigued by this issue and thus, initiated the project with an attempt to make a contribution to it with design methods.In the research phase, extensive literature constructed a holistic view of the loneliness and yielded a new perspective of understanding it. Loneliness is like the destination of the vicious circle between negative social interaction and negative social cognition. Moreover, it may spread through negative interaction. Thereby, the project focuses on social interaction as the entry point for intervention. Through partnering with Vierstroom, one elderly home care company who is also interested in connecting their elderly members, the project finds a context for designer’s intervention. It is activities organized by the Vierstroom and Palet welfare such as bingo game, or care lecture. Investigation of the context revealed dozens of problems and opportunities. There are five pain points highlighted in the elderly activity: the reliance of facilitator, the passive social attitude, the negative social norm, the negative complaining and the one-way communication.A new relationship between elderly and organization: sports fan and coachAnalysis and ideation provoke a vision that elderly and organization could be like sports fan and coach. With service design methods, the author paves the road to vision by seeing the activity as multiple-layers and sequential interaction. After that, a service strategy is synthesized with four steps for four sub-visions. Moreover, the strategy is translated into 15 design guidelines. Thereby, organizations could adopt the guidelines to enhance their service or generative service ideas in various cases. <br/
Développement économique et relations interethniques dans deux villages du nord du bassin de Vang Vieng au Laos. Ban Phatang (village lao) et Ban Somsavath (village yao)
No full textWhile, in the past, the population of the Yao village of Ban Somsavath used to live in mountain villages and the Lao population of Ban Phatang in the valley, both villages are now part of the economic development dynamics that characterizes the Vang Vieng basin in the Lao PDR. As a result, the long lasting economic and social relationship between the populations of the two villages has evolved, striking a new balance between friendship, complementarity and competition. In this paper, after discussing the political reasons for the establishment of Ban Phatang in the valley, the author defines the respective economic development strategies of the two villages and studies the present evolution of their enduring inter-ethnic relations.Autrefois village de vallée et village de montagne, l’un lao et l’autre yao, Ban Phatang et Ban Somsavath se retrouvent pris dans une même dynamique de développement propre au bassin de Vang Vieng au Laos. Leurs relations, à la fois économiques et sociales, établies de longue date, se sont transformées et consolidées entre amitié, complémentarité et concurrence. Cet article montre d’abord comment les conditions politiques ont amené les deux villages à se côtoyer dans la vallée. Dans un second temps il analyse les différentes stratégies de développement économique qu’ils ont élaborées. Enfin dans une troisième partie, il étudie l’évolution actuelle des liens interethniques anciens tissés entre ces deux villages.Charlet-Phommachanh Marieke. Développement économique et relations interethniques dans deux villages du nord du bassin de Vang Vieng au Laos. Ban Phatang (village lao) et Ban Somsavath (village yao). In: Aséanie 21, 2008. pp. 89-114
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