115,289 research outputs found
Ceramide Glycanase Activities in Human Cancer Cells
No full textCeramide glycanase (CGase) activities have been detected in different human tumor cells (colon, carcinoma Colo-205; neuroblastoma, IMR-32; breast cancer lines, SKBr3 and MCF7). However, the level of enzymatic activity is lower in these cells compared to that present in other mammalian tissues reported before (Basu, M., Kelly, P., Girzadas, M. A., Li, Z., and Basu, S. Methods Enzymol. (in press)). The majority of CGase activity was found in the 100,000g soluble supernatant fraction isolated from all these cell lines and tissues. Using the soluble enzyme, the requirement for optimum CGase activity was found to be consistent with previous observations found for rat and rabbit tissues (Basu, M., Dastgheib, S., Girzadas, M. A., O'Donnell, P. H., Westervelt, C. W., Li, Z., Inokuchi, J. I., and Basu, S. (1998) Acta Pol. Biochim. 42:327). The CGase activities from both Colo-205 and IMR-32 cells are optimum at a protein to detergent ratio of one. All the mammalian CGases, including human cancer cells, show an optimum pH between 5.5 and 5.8 in sodium acetate buffer. The CGase activities from cancer cells are found to be cation-independent; however, mercury, zinc, and copper ions seem to inhibit the enzyme activity substantially in both tumor cells lines. The mercury ion inhibition of CGase activities from ail different sources indicates a possible structural homology in the CGase proteins. Radiolabeled substrates, labeled at the sphingosine double bond or at the 3-position of sphingosine without modifying double bond of sphingosine were used in this investigation. Both were active substrates with all enzyme preparations isolated from different cancer cells (apparent Km, 500 mu M for nLcOse5[H-3-DT]Cer and 350 mu M for GgOse4[sph-3-H-3]Cer with Colo-205 enzyme). Structural analogues of ceramide and sphingosine (L-PPMP, L-PDMP, alkylamines, and Tamoxifen) inhibited cancer cell CGase activities in vitro
Synthesis, characterization of some diorganotin(IV) complexes of Schiff bases derived from a non-protein amino acid. Crystal structures of {HO2CC6H4[N=C(H){C(CH3)CH(CH3)-3-OH]-p} and its di-n-butyltin(IV) complex (nBu2Sn{O2CC6H4[N=C(H){C(CH3)CH(CH3)-3-OH]-p}2)
No full textDiorganotin(IV) complexes R2Sn(LH)2 (R = Me, nBu) and {[nBu2Sn(LH)]2O}2 (LH = 4-[(2Z)-(3-hydroxy-1-methyl-2-
butenylidene)amino]benzoate and 4-[{(E)-1-(2-hydroxyphenyl)methylidene}mino]benzoate) have been reported. The complexes
were characterized by elemental analysis, IR, NMR (1H, 13C, 119Sn) and 119mSn M ̈ ossbauer spectroscopy.
Crystal structures of a ligand {HO2CC6H4[N C(H)}{C(CH3)CH(CH3)-3-OH]-p} and one of its di-n-butyltin(IV) complexes
(nBu2Sn{O2CC6H4[N C(H)}{C(CH3)CH(CH3)-3-OH]-p}2) were determined. The spectroscopic data suggest that R2Sn(LH)2
complexes have skew-trapezoidal bipyramidal structure while {[nBu2Sn(LH)]2O}2 complexes adopt a dimeric tetraorganodistannoxane
structure in the solid state and undergo complex exchange processes in deuterochloroform solution, as
revealed by 119Sn NMR spectroscopy
Consistent estimation of conditional conservatism
No full textIn this paper, we propose an econometric model that presents three advantages in relation to the Basu model: (1) it is robust to the aggregation problem; that is, we prove that the Basu model produces inconsistent estimations of conditional conservatism and that this problem is solved with our proposal; (2) it can produce firm-specific measures of conservatism by using time-series; and (3) it completes the understanding of the intercept in the Basu model by breaking it down between unconditional conservatism and the reversion of the differences between market and book values of equity. In other words, we can provide firm-specific measures of both conditional and unconditional conservatism with the same model. We demonstrate all these theoretical assertions using simulated dataAccounting conservatism, Conditional conservatism, Unconditional conservatism, The Basu model, Aggregation effect
Struktur dramatik lakon budhug basu sajian Ki Anom Rusmanto H. Toma Putra dalam acara nadran di desa mundu kabupaten cirebon
No full textPenelitian ini mengkaji struktur dramatik lakon Budhug Basu sajian Ki Anom Rusmanto H. Toma Putra dalam acara nadran di pesisir Cirebon. Penelitian ini merupakan penelitian kualitatif dengan pendekatan tekstual, dan metode deskriptif-analitis, yang bertujuan untuk mengungkap struktur dramatik Lakon Budhug Basu sajian Ki Anom Rusmanto H. Toma Putra yang disajikan selama dua jam. Data didapatkan melalui tayangan YouTube. Penelitian ini menggunakan teori Sambung-Rapet menurut Aris Wahyudi. Sambung-Rapet adalah kaidah yang berkenaan dengan upaya membangun jalinan antar peristiwa dalam lakon berdasarkan unsur-unsur tema, alur, penokohan, dan setting yang terintegrasi membentuk kesatuan cerita. Pola-pola hubungan antar elemen ini menjadikan lakon Budhug Basu tidak hanya utuh secara struktural, tetapi juga tetap relevan dalam konteks pertunjukan tradisional. Penggunaan teori Sambung-Rapet berhasil mengungkap pola kesinambungan antar bagian cerita dan memperlihatkan bagaimana dalang membangun yang kesatuan dramatik kohesif dalam waktu pementasan yang terbatas (dua jam
Struktur Dramatik Lakon Budhug Basu Sajian Ki Anom Rusmanto H. Toma Putra Dalam Acara Nadran Di Desa Mundu Kabupaten Cirebon
No full textPenelitian ini mengkaji struktur dramatik lakon Budhug Basu sajian Ki Anom Rusmanto H. Toma Putra dalam acara nadran di pesisir Cirebon. Penelitian ini merupakan penelitian kualitatif dengan pendekatan tekstual, dan metode deskriptif-analitis, yang bertujuan untuk mengungkap struktur dramatik Lakon Budhug Basu sajian Ki Anom Rusmanto H. Toma Putra yang disajikan selama dua jam. Data didapatkan melalui tayangan YouTube. Penelitian ini menggunakan teori Sambung-Rapet menurut Aris Wahyudi. Sambung-Rapet adalah kaidah yang berkenaan dengan upaya membangun jalinan antar peristiwa dalam lakon berdasarkan unsur-unsur tema, alur, penokohan, dan setting yang terintegrasi membentuk kesatuan cerita. Pola-pola hubungan antar elemen ini menjadikan lakon Budhug Basu tidak hanya utuh secara struktural, tetapi juga tetap relevan dalam konteks pertunjukan tradisional. Penggunaan teori Sambung-Rapet berhasil mengungkap pola kesinambungan antar bagian cerita dan memperlihatkan bagaimana dalang membangun yang kesatuan dramatik kohesif dalam waktu pementasan yang terbatas (dua jam)
Benchmarking the Effective Literacy Rate
No full textBy now the importance of literacy in the process of development is widely accepted. However, unlike measuring welfare or inequality, the problem of literacy measurement remains largely unexamined. Alternatives to the standard literacy rate, R, equal to the number of literate adults as a percentage of the adult population, are not well known, but this measure has its deficiencies. In particular, several authors have identified the externality accruing to proximate illiterates, that is, illiterate people with access to a literate person. The standard literacy rate ignores this externality; measures of effective literacy are sensitive to it. The present note offers two effective literacy rates (measures) and a set of axioms characterizing each. Nearly all measures of effective literacy appearing in the literature are greater than or equal to R. In fact, the best known of these, the Basu-Foster measure L*, is strictly greater in virtually every case (see Basu and Foster [1]). Although the inequality L* >= R is an unintended consequence of their construction, it amounts to setting a benchmark for the effective literacy rate. This notes examines Basu and Foster's framework and offers an alternative benchmark.
Helene Basu, Von Barden und Königen. Ethnologische Studien zur Göttin und zum Gedächtnis in Kacch (Indien)
No full textPar sa dimension théorique, l’intérêt de cette étude dépasse de loin celle d’un groupe social particulier de la région du Kacch (dans l’État du Gujerat, proche du Pakistan), où Helene Basu a, à plusieurs reprises, séjourné et enquêté et dont elle a une excellente connaissance. Ce travail, indique H. Basu dans l’introduction, se situe dans le champ de tension entre remémoration, qui est actualisation du passé et conscience d’un présent que le rappel conscient de ce passé éclaire et contri..
Oncidium stenoglossum Dressler & N. H. Williams, Orquidea
No full textOncidium stenoglossum (Schltr.) Dressler & N.H.Williams, Orquídea (Mexico City), n.s., 4(11): 339. 1975. Voucher: H. Vega 167 (TEFH).Published as part of Vega, Hermes, Cetzal-Ix, William, Mó, Edgar, Romero-Soler, Katya J. & Basu, Saikat K., 2022, An Updated Checklist of the Orchidaceae of Honduras, pp. 1-80 in Phytotaxa 562 (1) on page 64, DOI: 10.11646/phytotaxa.562.1.1, http://zenodo.org/record/707369
Helene Basu, Von Barden und Königen. Ethnologische Studien zur Göttin und zum Gedächtnis in Kacch (Indien)
No full textPar sa dimension théorique, l’intérêt de cette étude dépasse de loin celle d’un groupe social particulier de la région du Kacch (dans l’État du Gujerat, proche du Pakistan), où Helene Basu a, à plusieurs reprises, séjourné et enquêté et dont elle a une excellente connaissance. Ce travail, indique H. Basu dans l’introduction, se situe dans le champ de tension entre remémoration, qui est actualisation du passé et conscience d’un présent que le rappel conscient de ce passé éclaire et contri..
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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