14 research outputs found
Game-like interactive exercise versus visual feedback in patients with chemotherapy induced peripheral neuropathy post mastectomy: A randomized comparative study
No full textBackground Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most frequent side effects of antineoplastic agents, with a prevalence of 19 to 85%. In terms of clinical manifestations, CIPN is primarily a sensory neuropathy with motor and autonomic alterations of varying intensity and duration. CIPN consider as major problem for both cancer patients and survivors, as well as for their healthcare providers, possibly increasing the risk of falling. Objective: To evaluate the efficacy of game-like interactive exercise versus visual feedback training on the risk of falling and sensory integration in patients with chemotherapy-induced peripheral neuropathy after mastectomy. Methods: In this randomized comparative study, 30 female patients diagnosed with chemotherapy-induced peripheral neuropathy after mastectomy were randomly allocated into two equal groups; group (A) underwent game-like interactive exercise using the Biodex Balance System (BBS), while group (B) underwent a visual feedback training program using BBS. The treatment was applied for three sessions per week for four consecutive weeks. All subjects in both groups were assessed using the fall risk index and sensory integration test (sway index) in four sensory conditions at baseline and at the end of the study for both groups
The role of Plasmodium falciparum var genes in malaria in pregnancy
No full textSequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected erythrocytes binding to host receptors in the placenta such as chondroitin sulphate A (CSA). Identification of the parasite ligand(s) responsible for placental adhesion could lead to the development of a vaccine to induce antibodies to prevent placental sequestration. Such a vaccine would reduce the maternal anaemia and infant deaths that are associated with malaria in pregnancy. Current research indicates that the parasite ligands mediating placental adhesion may be members of the P. falciparum variant surface antigen family PfEMP1, encoded by var genes. Two relatively well-conserved subfamilies of var genes have been implicated in placental adhesion, however, their role remains controversial. This review examines the evidence for and against the involvement of var genes in placental adhesion, and considers whether the most appropriate vaccine candidates have yet been identified
Virtual reality-based exercises to improve balance and hand grip strength in patients with hemiparesis caused by an electrical burn: A randomized controlled study
No full textThere are many complications after an electrical burn injury, including neuromuscular defects, paresis or paralysis, Gillian barre syndrome, transverse myelitis, or amyotrophic lateral sclerosis. The aim of this study was to investigate the effect of virtual reality-based exercises on balance and hand grip strength in post electrical burn-induced hemiparetic patients. A randomized control trial pre- and post-experimental design with intra-rater reliability and inter-rater agreement was undertaken. Thirty post-electrical burn-induced hemiparetic patients (19 males and 11 females, aged 15 to 25 years) were randomly allocated into two equal groups (group A and B). Group A (n = 15) received virtual reality-based exercise in addition to the conventional physical therapy program. Group B (n = 15) received conventional physical therapy program only. The treatment was applied 3 sessions per week for 12 consecutive weeks. Posture stability and hand grip strength were measured by the Biodex balance system and handheld dynamometer, respectively. Data was collected prior to the first treatment and at the end of the 12-week trial and all statistical calculations were done using the computer program IBM SPSS. A statistically significant increase in the overall stability index and the power of hand grip strength was observed in both groups after treatment (p < 0.05), especially in group A, which received VR - based exercise training. Thus, group A showed a greater improvement in postural stability and hand grip strength than group B (p < 0.05). Virtual reality-based exercises as well as conventional physical therapy program were effective in improving posture stability and hand grip strength in post electrical burn-induced hemiparetic patients
Virtual reality-based exercises to improve balance and hand grip strength in patients with hemiparesis caused by an electrical burn: A randomized controlled study
No full textThere are many complications after an electrical burn injury, including neuromuscular defects, paresis or paralysis, Gillian barre syndrome, transverse myelitis, or amyotrophic lateral sclerosis. The aim of this study was to investigate the effect of virtual reality-based exercises on balance and hand grip strength in post electrical burn-induced hemiparetic patients. A randomized control trial pre- and post-experimental design with intra-rater reliability and inter-rater agreement was undertaken. Thirty post-electrical burn-induced hemiparetic patients (19 males and 11 females, aged 15 to 25 years) were randomly allocated into two equal groups (group A and B). Group A (n = 15) received virtual reality-based exercise in addition to the conventional physical therapy program. Group B (n = 15) received conventional physical therapy program only. The treatment was applied 3 sessions per week for 12 consecutive weeks. Posture stability and hand grip strength were measured by the Biodex balance system and handheld dynamometer, respectively. Data was collected prior to the first treatment and at the end of the 12-week trial and all statistical calculations were done using the computer program IBM SPSS. A statistically significant increase in the overall stability index and the power of hand grip strength was observed in both groups after treatment (p < 0.05), especially in group A, which received VR - based exercise training. Thus, group A showed a greater improvement in postural stability and hand grip strength than group B (p < 0.05). Virtual reality-based exercises as well as conventional physical therapy program were effective in improving posture stability and hand grip strength in post electrical burn-induced hemiparetic patients
Moringa Oleifera Extract as Green Corrosion Inhibitor for Zinc in Polluted Sodium Chloride Solutions *Corresponding Author
No full textIn this work, moringa extract was examined as a green corrosion inhibitor for zinc in 3.5 % NaCl and 16 ppm solution by using weight loss, potentiodynamic polarization, electrochemical impedance spectroscopy (EIS) and electrochemical frequency modulation (EFM) techniques. Results obtained showed that this extract of moringa offered good protection against corrosion of zinc metal and exhibited high inhibition efficiencies. The inhibition efficiency was found to increase with increase in the extract concentration. The adsorption of the inhibitor molecules on the zinc metal surface follows Temkin adsorption isotherm and behaves as mixed type inhibitor
Game-like Interactive Exercise Versus Visual Feedback in Patients with Chemotherapy Induced Peripheral Neuropathy Post Mastectomy: A Randomized Comparative Study
No full textBackground Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most frequent side effects of antineoplastic agents, with a prevalence of 19 to 85%. In terms of clinical manifestations, CIPN is primarily a sensory neuropathy with motor and autonomic alterations of varying intensity and duration. CIPN consider as major problem for both cancer patients and survivors, as well as for their healthcare providers, possibly increasing the risk of falling. Objective: To evaluate the efficacy of game-like interactive exercise versus visual feedback training on the risk of falling and sensory integration in patients with chemotherapy-induced peripheral neuropathy after mastectomy. Methods: In this randomized comparative study, 30 female patients diagnosed with chemotherapy-induced peripheral neuropathy after mastectomy were randomly allocated into two equal groups; group (A) underwent game-like interactive exercise using the Biodex Balance System (BBS), while group (B) underwent a visual feedback training program using BBS. The treatment was applied for three sessions per week for four consecutive weeks. All subjects in both groups were assessed using the fall risk index and sensory integration test (sway index) in four sensory conditions at baseline and at the end of the study for both groups
Transtheoretical Model-based Interventions are Effective in Promoting Healthy Behaviors Related to Modifiable Risk Factors of Noncommunicable Diseases: A Systematic Review
No full textIntroduction: Noncommunicable diseases (NCDs) such as heart diseases, type II diabetes mellitus, cancers, and stroke represent significant public health challenges globally. Modifiable risk factors, including insufficient physical activity (PA), overweight or obesity, and smoking, contribute significantly to the prevalence of these diseases. The transtheoretical model (TTM) offers a structured approach to behavior change, identifying stages of readiness and change processes. This systematic review (SR) aims to evaluate the effectiveness of TTM-based interventions in promoting healthy behaviors to mitigate these risk factors.
Methods: This systematic review addresses the PICO question: In adults aged 18 years and older with modifiable risk behaviors related to NCDs, how effective are TTM-based interventions compared to standard care in increasing physical activity levels (PAL), reducing weight or body mass index, improving dietary habits, and promoting smoking cessation (SC)? A comprehensive search of predetermined databases was conducted using nine research strings, adhering to strict inclusion and exclusion criteria. A six-stage process was employed to select studies for inclusion, followed by data extraction and narrative synthesis to identify relevant patterns, trends, and associations.
Results: Of the 259 articles retrieved, eight met the inclusion criteria. Baseline assessments determined participants’ readiness for change. TTM-based interventions included feedback or counseling sessions, feedback materials, and reports delivered in-person, online, and by telephone. Follow-up durations varied from 2 weeks to 2 years. Five out of six studies supported the effectiveness of TTM-based interventions in enhancing PAL. Four out of five studies demonstrated their efficacy in weight management and improving dietary habits. However, only two out of five studies confirmed their effectiveness in SC.
Discussion: The findings indicate that TTM-based interventions are promising for improving PAL and, to a lesser extent, for managing weight and promoting healthy dietary behaviors. The limited effectiveness observed in SC interventions suggest a need for further research and possibly tailored strategies within this context.
Conclusion: TTM-based interventions effectively promote PA and weight management, with moderate success in improving dietary habits. However, their effectiveness in SC remains inconclusive, highlighting the necessity for further investigation and potential refinement of intervention strategies
Comparison Between Botulinum Toxin A Injection and Lacrimal Punctal Plugs for the Control of Post-LASIK Dry Eye Manifestations: A Prospective Study
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Life cycle and early development of the thecosomatous pteropod Limacina retroversa in the Gulf of Maine, including the effect of elevated CO2 levels
No full textAuthor Posting. © The Author(s), 2015. This is the author's version of the work. It is posted here by permission of Springer for personal use, not for redistribution. The definitive version was published in Marine Biology 162 (2015): 2235-2249, doi:10.1007/s00227-015-2754-1.Thecosome pteropods are pelagic molluscs with aragonitic shells. They are considered to be especially vulnerable among plankton to ocean acidification (OA), but to recognize changes due to anthropogenic forcing a baseline understanding of their life history is needed. In the present study, adult Limacina retroversa were collected on five cruises from multiple sites in the Gulf of Maine (between 42° 22.1’–42° 0.0’ N and 69° 42.6’–70° 15.4’ W; water depths of ca. 45–260 m) from October 2013−November 2014. They were maintained in the laboratory under continuous light at 8° C. There was evidence of year-round reproduction and an individual life span in the laboratory of 6 months. Eggs laid in captivity were observed throughout development. Hatching occurred after 3 days, the veliger stage was reached after 6−7 days, and metamorphosis to the juvenile stage was after ~ 1 month. Reproductive individuals were first observed after 3 months. Calcein staining of embryos revealed calcium storage beginning in the late gastrula stage. Staining was observed in the shell gland, shell field, mantle, and shell margin in later stages. Exposure of two batches of larvae at the gastrula stage to elevated CO2 levels (800 and 1200 ppm) resulted in significantly increased mortality in comparison with individuals raised under ambient (~400 ppm) conditions and a developmental delay in the 1200 ppm treatment compared with the ambient and 800 ppm treatments.A. Thabet is grateful for a fellowship from the Egyptian Culture and Education Bureau and for mentoring from Drs. S.A. Saber, M.M. Sarhan and M.M. Fouda. Funding for this research was provided by a National Science Foundation grant to Lawson, Maas, and Tarrant (OCE-1316040). Additional support for field sampling was provided by the WHOI Coastal Ocean Institute and Pickman Foundation to Wang, Maas, and Lawson.2016-10-2
Assembly of a reference transcriptome for the gymnosome pteropod Clione limacina and profiling responses to short-term CO2 exposure
No full text© The Author(s), 2017. This is the author's version of the work. It is posted here under a nonexclusive, irrevocable, paid-up, worldwide license granted to WHOI. It is made available for personal use, not for redistribution. The definitive version was published in Marine Genomics 34 (2017): 39-45, doi:10.1016/j.margen.2017.03.003.The gymnosome (unshelled) pteropod Clione limacina is a pelagic predatory mollusc found in
polar and sub-polar regions. It has been studied for its distinctive swimming behavior and as an
obligate predator on the closely related thecosome (shelled) pteropods. As concern about ocean
acidification increases, it becomes useful to compare the physiological responses of closely-related calcifying and non-calcifying species to acidification. The goals of this study were thus to
generate a reference transcriptome for Clione limacina, to expose individuals to CO2 for a period
of 3 days, and to explore differential patterns of gene expression. Our Trinity assembly contained
300,994 transcripts of which ~26% could be annotated. In total, only 41 transcripts were
differentially expressed following the CO2 treatment, consistent with a limited physiological
response of this species to short-term CO2 exposure. The differentially expressed genes
identified in our study were largely distinct from those identified in previous studies of
thecosome pteropods, although some similar transcripts were identified, suggesting that
comparison of these transcriptomes and responses may provide insight into differences in OA
responses among phylogenetically and functionally distinct molluscan lineages.A. Thabet is grateful for a fellowship from the Egyptian Culture and Education Bureau and for
mentoring from Drs. M.M. Sarhan and M.M. Fouda. Funding for this research was provided by a
National Science Foundation grant to Lawson, Maas, and Tarrant (OCE-1316040)
