19 research outputs found
Influenza aerosols in UK hospitals during the influenza H1N1 (2009–10) pandemic: air sampling in the vicinity of patients undergoing WHO-defined aerosol generating procedures
Influenza aerosols in UK hospitals during the H1N1 (2009) pandemic - the risk of aerosol generation during medical procedures
With our small sample size we found that AGPs do not significantly increase the probability of sampling an H1N1 (2009) positive aerosol (OR (95% CI)?=?4.31 (0.83-22.5). Although the probability of detecting positive H1N1 (2009) positive aerosols when performing various AGPs on intensive care patients above the baseline rate (i.e. in the absence of AGPs) did not reach significance, there was a trend towards hierarchy of AGPs, placing bronchoscopy and respiratory and airway suctioning above baseline (background) values. Further, larger studies are required but these preliminary findings may be of benefit to infection control teams
Spread of a multiresistant strain of Pseudomonas aeruginosa in an adult cystic fibrosis clinic
We initiated a prospective surveillance study to investigate possible Pseudomonas aeruginosa cross-infection in our cystic fibrosis centre. We characterised isolates by pyocin typing and pulsed-field gel electrophoresis. 22 (14%) of 154 patients with chronic P aeruginosa had isolates with similar and new pyocin and pulsed-field gel electrophoresis types. The shared isolates showed unusual phenotypic features: they were non-pigmented, non-motile, and resistant to a number of antipseudomonal antibiotics. Cross-infection by a multiresistant P aeruginosa strain has therefore occurred in patients attending our cystic fibrosis centre. We recommend microbiological surveillance in other cystic fibrosis centres
Spread of a multiresistant strain of Pseudomonas aeruginosa in an adult cystic fibrosis clinic
We initiated a prospective surveillance study to investigate possible Pseudomonas aeruginosa cross-infection in our cystic fibrosis centre. We characterised isolates by pyocin typing and pulsed-field gel electrophoresis. 22 (14%) of 154 patients with chronic P aeruginosa had isolates with similar and new pyocin and pulsed-field gel electrophoresis types. The shared isolates showed unusual phenotypic features: they were non-pigmented, non-motile, and resistant to a number of antipseudomonal antibiotics. Cross-infection by a multiresistant P aeruginosa strain has therefore occurred in patients attending our cystic fibrosis centre. We recommend microbiological surveillance in other cystic fibrosis centres
Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium.
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Demographic and patient specific conditions of air samples.
a<p>Sample considered positive if aerosol <7.3 µm indicated the present of H1N1.</p>b<p>n unique patients refers to the number of patients these samples were taken from.</p><p>Column A: Results from univariable logistic regression models examining potential risk factors for production of H1N1 positive aerosol. Sample considered positive if aerosol <7.3 µm indicated the presence of H1N1. Estimates adjusted for repeated measurements.</p><p>Column B: Results from univariable negative binomial regression models examining potential risk factors for copy number per litre per minute given H1N1 positive aerosol.</p><p>A hyphen (-) indicates no positive samples in category. Referent refers to the category of an ordinal or nominal variable against which other categories are compared in the regression model and for which <i>no</i> dummy variable is included in the regression model.</p
Analysis of air samples using the WHO (2009) AGP definitions.
a<p>Sample considered positive if aerosol <7.3 µm indicated the present of H1N1.</p>b<p>n unique patients refers to the number of patients these samples were taken from.</p><p>Column A: Results from univariable logistic regression models examining potential risk factors for production of H1N1 positive aerosol. Sample considered positive if aerosol <7.3 µm indicated the presence of H1N1. Estimates adjusted for repeated measurements.</p><p>Column B: Results from univariable negative binomial regression models examining potential risk factors for copy number per litre per minute given H1N1 positive aerosol.</p><p>A hyphen (-) indicates no positive samples in category. Referent refers to the category of an ordinal or nominal variable against which other categories are compared in the regression model and for which <i>no</i> dummy variable is included in the regression model.</p
The percentage of total RNA collected in each stage (size range) of the May impinger compared based on the WHO 2009 AGP definitions.
<p>The percentage of total RNA collected in each stage (size range) of the May impinger compared based on the WHO 2009 AGP definitions.</p
The recruitment and data analysis flowchart.
<p>The recruitment and data analysis flowchart.</p
Analysis of air samples using the WHO (2007) AGP definitions.
a<p>Sample considered positive if aerosol <7.3 µm indicated the present of H1N1.</p>b<p>n unique patients refers to the number of patients these samples were taken from.</p><p>Column A: Results from univariable logistic regression models examining potential risk factors for production of H1N1 positive aerosol. Sample considered positive if aerosol <7.3 µm indicated the presence of H1N1. Estimates adjusted for repeated measurements.</p><p>Column B: Results from univariable negative binomial regression models examining potential risk factors for copy number per litre per minute given H1N1 positive aerosol.</p><p>A hyphen (-) indicates no positive samples in category. Referent refers to the category of an ordinal or nominal variable against which other categories are compared in the regression model and for which <i>no</i> dummy variable is included in the regression model.</p
