1,721,057 research outputs found

    Stiff left atrial syndrome after low-dose radiotherapy for right breast cancer: The need for invasive hemodynamics at exercise

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    Stiff left atrial (LA) syndrome is a distinct phenotype of heart failure with preserved ejection fraction, characterized by predominant high LA pressure. We describe the case of a middle-aged woman who developed exertional breathlessness during low-dose radiotherapy for right breast cancer and who was eventually found to be affected by stiff LA syndrome. Invasive hemodynamics allowed the recognition of pathognomonic tall V waves in the wedge position during exercise, in spite of inconclusive noninvasive investigations

    New trends in optical resonant bio-chemical sensing

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    The development of innovative bio-chemical sensors is of great importance to make new devices available to the market. In the current paper, we review recent trends on optical resonant sensors that may involve plasmonic or geometrical resonances. In all cases, resonance is activated by excitation with electromagnetic light of proper wavelength. Plasmonic hot electrons, obtained by shining light on metal nanoparticle decorated metal oxides, can bring new effects in physicochemical processes, affecting electrical and optical properties (absorption/transmission, Surface Enhanced Raman Spectroscopy SERS). Geometrical resonances are involved in Mie and Whispering Gallery Modes (WGM) based sensing, including metasurfaces for optical detection of molecules and nonlinear effects in metamaterials

    Study of the degradation of biobased plastic after stress tests in water

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    Research on compostable bioplastics has recently obtained performances comparable to traditional plastics, like water vapor permeability, sealability, and UV transmission. Therefore, it is crucial to create new tools that help the developers of new polymeric composites study them quickly and cost-effectively. In this work, Raman spectroscopy (RS) was proposed as a versatile tool to investigate the degradation of biobased plastics after a stress test in water: this approach is a novelty for food packaging. Treatments at room temperature (RT) and 80◦ C were selected, considering that these biopolymers can be used to packaging ready meals. The investigation was carried out on single-layer sheets of poly-lactic acid (PLA), cellulose ester (CE), poly-butylene succinate (PBS), polybutylene adipate-co-terephthalate (PBAT), and a new composite material obtained by coupling CE and PBS (BB951) and PLA and CE (BB961). The vibrational modes of the water-treated materials at RT and 80◦ C were compared to the Raman spectra of the pristine bioplastic, and the morphologies of the polymers were analyzed by scanning electron microscopy (SEM) and optical microscopy. Composite sheets were the plastics which were mostly affected by the 80◦ C treatment in water, through changes in morphology (wrinkling with alternate white and transparent zones), as was especially the case for BB951. The Raman spectra acquired in different zones showed that the vibrations of BB951 were generally maintained in transparent zones but reduced or lacking in white zones. At the same time, the single-layer materials were almost unchanged. For BB961, the Raman vibrations were only slightly modified, in agreement with the visual inspection. The results suggest that RS detects the specific chemical bond that was modified, helping us understand the degradation process of biobased plastics after water treatment

    Early Detection of Esca Disease in Asymptomatic Vines by Raman Spectroscopy

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    Early detection of esca disease in grapevines is fundamental to calibrating proper pesticide use in sustainable vineyard management systems. This article is a proof of concepts showing that the Raman spectroscopy (RS) combined with a chemometric analysis can be used as a nondestructive sensor to implement precision agriculture for early detection of the disease through a new biochemical marker. Symptomatic and symptomless branches from an esca-developing vine and from healthy esca-free vines from a vineyard were investigated by RS and chemometrics, using the final outcome of the specific disease syndrome as the final benchmark. As a result, the model is always able to correctly classify all the test samples, showing auspicious results to perform precision agriculture-based future therapeutic approaches

    Corrigendum: The atrial secondary tricuspid regurgitation is associated to more favorable outcome than the ventricular phenotype

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    In the published article, there was an error in affiliation (2) for the following 3 authors: Mara Gavazzoni, Michele Tomaselli, Claudia Baratto. The affiliation (2) “Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy” does not apply to these three authors. The only affiliation for these authors should be (1): “Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy”, as displayed in the new version of the paper. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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