1,720,957 research outputs found
Eksperimentinės inkstų transplantacijos Lietuvoje apžvalga
Get PDFBalys Dainys, Tatjana Rainienė
Vilniaus universiteto Nefrologijos ir urologijos centras
VšĮ Vilniaus universiteto ligoninė Santariškių klinikos,
Santariškių g. 2, LT-08661 Vilnius
El paštas: [email protected]
Pirmasis eksperimentinę inksto transplantaciją Lietuvoje atliko V. Kuzma. 1925 m. nuvykęs tobulintis į Vieną, į A. Eiselsbergo kliniką, transplantacijos eksperimentus darė kartu su dr. E. Goldu. Grįžęs į Kauną, 1927–1929 metais tęsė eksperimentines inkstų autotransplantacijas, alotransplantacijas ir ksenotransplantacijas. Jis sukūrė originalų inkstų alotransplantacijos ir ksenotransplantacijos modelį parabiozės sąlygomis, kai sudaroma donoro ir recipiento kryžminė kraujotaka.
Inkstų transplantacijos eksperimentai Lietuvoje buvo vėl pradėti 1964 metais Vilniaus universiteto Širdies ir kraujagyslių chirurgijos laboratorijoje. Šie eksperimentiniai tyrimai turėjo svarbią reikšmę pradedant Vilniuje klinikinę inkstų transplantaciją 1970 metais.
Reikšminiai žodžiai: eksperimentinė inksto transplantacija, autotransplantacija, alotransplantacija, ksenotransplantacija, transplantologijos istorija
A retrospect of experimental renal transplantations in Lithuania
Balys Dainys, Tatjana Rainienė
Vilnius University, Center of Nephrology and Urology,
Santariškių g. 2, LT-08661 Vilnius, Lithuania
E-mail: [email protected]
V. Kuzma was a suergeon who performed the first experimental renal transplantation in Lithuania. He gained his first experience in experimental organ and tissue transplantation in Vienna, where he cooperated with Dr. Gold, member of A. Eiselsberg’s team. In Kaunas, V. Kuzma proceeded his experiments on kidney autotransplantations, allotransplantations and xenotransplantations. He performed renal allotransplations and xenotransplantations in parabiosis conditions when cross blood circulation between the donor and the recipient was created. V. Kuzma carried out the above-mentioned experiments in Kaunas University in 1927–1929. Experiments on renal transplantations were started again in 1964 at Laboratory of Cardiovascular Surgery of Vilnius University. This experience was valuable for clinical renal transplantation started in Vilnius in 1970.
Keywords: experimental renal transplantation, autotransplantation, allotransplantation, xenotransplantation, history of transplantolog
Transuretrinės mikrobangų termoterapijos ankstyvieji ir vėlyvieji rezultatai gydant nepiktybinę prostatos hiperplaziją
Get PDFAudrius Rimas, Balys Dainys
Vilniaus universiteto ligoninės Santariškių klinikos
Nefrologijos ir urologijos centras,
Santariškių g. 2, LT-08661 Vilnius
El paštas: [email protected], [email protected]
Tikslas
Apibendrinti ir įvertinti nepiktybinės prostatos hiperplazijos gydymo rezultatus, naudojant transuretrinę mikrobangų termoterapiją.
Ligoniai ir metodai
Retrospektyviai išanalizuoti 99 pacientų termoterapijos rezultatai. Gydytų vyrų amžiaus vidurkis – 71,9 metų. Ligoniai šiam gydymui atrinkti atsižvelgus į skundus, maksimalų šlapimo srovės greitį, transrektalinę prostatos echoskopiją ir liekamąjį šlapimą. Viršgaktiniu šlapimo pūslės drenažu gydytas 31 vyras. Šlapimo takų infekcija nustatyta 22 ligoniams prieš gydymą. Termoterapijai naudotas firmos "Dornier" aparatas "UroWave".
Rezultatai
Pagal Tarptautinę prostatos simptomų skalę skundai sumažėjo nuo 11,2 iki 7 balų (62,5%), prostatos tūris – nuo 70 ml iki 60 ml (15,7%), maksimalus srovės greitis padidėjo nuo 8 ml/s iki 15 ml/s (53,3%), liekamojo šlapimo kiekis liko nereikšmingas, pašalintos cistostomos 22 ligoniams iš 31 (70,1%), po 24 mėn. 7 ligoniai operuoti, 10 ligonių atlikta pakartotinė termoterapija, medikamentinis gydymas skirtas 20 ligonių. Pasiteikė šios komplikacijos: hematurija – 23 (23,3%) ligoniams; kraujavimas – vienam (1,01%); ūminis šlapimo susilaikymas – aštuoniems (8,08%); šlapimo takų infekcijos paūmėjimas – vienam (1,01%).
Išvados
Mikrobangų termoterapija yra veiksmingas ir saugus nepiktybinės prostatos hiperplazijos gydymo būdas. Simptominis ir urodinaminis pagerėjimas po termoterapijos išliko iki 24 mėnesių. Geriausias poveikis gautas 3–18 mėnesiais. Pavojingų sveikatai ir gyvybei komplikacijų po mikrobangų termoterapijos nepasitaikė. Šlapimo takų infekcija blogina termoterapijos rezultatą ankstyvuoju laikotarpiu, vėliau ligos baigčiai ji reikšmės neturi.
Reikšminiai žodžiai: nepiktybinė prostatos hiperplazija, transuretrinė mikrobangų termoterapija, hipertermija
Early and follow-up clinical results of transurethral microwave thermotherapy for benign prostatic hyperplasia
Audrius Rimas, Balys Dainys
Vilnius University Hospital "Santariškių klinikos",
Center of Nephrology and Urology,
Santariškių str. 2,
LT-08661 Vilnius, Lithuania
E-mail: [email protected], [email protected]
Objective
To evaluate the results of transurethral microwave thermotherapy for benign prostatic hyperplasia.
Patients and methods
The results of thermotherapy were analysed retrospectively for 99 cases of prostatic hyperplasia. The mean age of patients was 71.9 years. Initial evaluation consisted of a history, peak urinary flow rate, transrectal prostate ultrasonography and post-voiding urinary volume. Suprapubic urinary drainage was done in 31 cases. Urinary tract pre-infection was found in 22 patients. We used a UroWave (Dornier) device for thermotherapy.
Results
The complaints according to IPSS decreased from 11.2 to 7 (62.5%), the prostate volume from 70 to 60 ml (15.7%), the peak flow rate increased from 8 to 15 ml/s (53.3%), residual urinary volume was insignificant after treatment, cistostoms were removed in 22 cases from 31 (70.1%), after 24 months 7 patients were operated on, 10 patients underwent retreatment with thermotherapy, medication was administered in 20 cases. We noticed the following complications: hematuria in 23 (23.3%) patients, bleeding 1 (1.01%), acute retention of urination 8 (8.08%), exacerbation of urinary tract infection 1 (1.01%).
Conclusions
Microwave thermotherapy is an efficacious and safe method of treatment of benign prostatic hyperplasia. Symptomatic and urodynamic improvement after thermotherapy persisted for 24 months. The best results were obtained 3–18 months after treatment. We found no high-risk complications after thermotherapy. Urinary tract infection worsened the results of microwave thermotherapy only in the early post-treatment period.
Keywords: benign prostatic hyperplasia, transurethral microwave thermotherapy, hyperthermia, minimally invasive therap
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
- …
