101,921 research outputs found
Racing, ornamental and city pigeons carry Shiga toxin producing Escherichia coli (STEC) with different Shiga toxin subtypes, urging further analysis of their epidemiological role in the spread of STEC
Pigeons are known to shed zoonotic pathogens. Therefore, in this study a total of 366 droppings from pigeons were analysed using PCR and DNA-DNA-hybridization for Shiga toxin producing E coli (STEC). Specimens were collected from three different groups of pigeons: 247 collective and 3 individual droppings from racing pigeons, 26 collective and 40 individual from ornamental pigeons as well as 50 collective droppings from city pigeons. Initial screening experiments revealed a total 245 (66.9%) droppings to be Shiga toxin gene positive. Of these 36% were positive for stx1,9% for stx2 and 37% for stx2f. Prevalence significantly (p < 0.001) differed in regard to the pigeon groups examined. Droppings from racing pigeons showed prevalence of 45.6% for stx1,3.2% for stx2, and 33.2% for stx2f, while the distribution of stx-positive specimens was more even in ornamental pigeons (15% stx1, 27% stx2, and 26% stx2). In specimens from city pigeons, stx2f was found to be most prevalent with 76% (2% stx1, 16% stx2). In 161 samples, stx genes were detected by PCR as well as DNA-DNA-hybridization. From these 161 samples, 20 were randomly chosen for isolation of STEC. A total of 27 STEC strains were isolated from 13 of these 20 samples. Six of the STEC were positive for stx1, 21 harbored stx2f. Further typing for virulence factor genes revealed the existence of eae in 4 of the 6 stx1-positive strains, as well as in 19 of the 21 stx2f-positive strains. eae is known to be crucially involved in the ability of E coli strains to cause the "attaching and effacing" lesion in the gut, while stx2f-STEC are assumed to be host specific for pigeons. Here we report the first description of stx1- and eae-positive STEC strains in pigeons from Germany, especially in racing and ornamental pigeons. Taking into account the close contact between fanciers and pigeons, these findings warrant a more critical appraisal of these zoonotic pathogens in pigeons
Racing, ornamental and city pigeons carry Shiga toxin producing Escherichia coli (STEC) with different Shiga toxin subtypes, urging further analysis of their epidemiological role in the spread of STEC
Pigeons are known to shed zoonotic pathogens. Therefore, in this study a total of 366 droppings from pigeons were analysed using PCR and DNA-DNA-hybridization for Shiga toxin producing E coli (STEC). Specimens were collected from three different groups of pigeons: 247 collective and 3 individual droppings from racing pigeons, 26 collective and 40 individual from ornamental pigeons as well as 50 collective droppings from city pigeons. Initial screening experiments revealed a total 245 (66.9%) droppings to be Shiga toxin gene positive. Of these 36% were positive for stx1,9% for stx2 and 37% for stx2f. Prevalence significantly (p < 0.001) differed in regard to the pigeon groups examined. Droppings from racing pigeons showed prevalence of 45.6% for stx1,3.2% for stx2, and 33.2% for stx2f, while the distribution of stx-positive specimens was more even in ornamental pigeons (15% stx1, 27% stx2, and 26% stx2). In specimens from city pigeons, stx2f was found to be most prevalent with 76% (2% stx1, 16% stx2). In 161 samples, stx genes were detected by PCR as well as DNA-DNA-hybridization. From these 161 samples, 20 were randomly chosen for isolation of STEC. A total of 27 STEC strains were isolated from 13 of these 20 samples. Six of the STEC were positive for stx1, 21 harbored stx2f. Further typing for virulence factor genes revealed the existence of eae in 4 of the 6 stx1-positive strains, as well as in 19 of the 21 stx2f-positive strains. eae is known to be crucially involved in the ability of E coli strains to cause the "attaching and effacing" lesion in the gut, while stx2f-STEC are assumed to be host specific for pigeons. Here we report the first description of stx1- and eae-positive STEC strains in pigeons from Germany, especially in racing and ornamental pigeons. Taking into account the close contact between fanciers and pigeons, these findings warrant a more critical appraisal of these zoonotic pathogens in pigeons
Bibliographie Hilarion G. Petzold 1958 – 2009 mit Anhang als Einführung
Dieses Archiv enthält die Gesamtbibliographie der Werke des Autors nebst einiger Texte „Über H. G. Petzold“ im Schlussteil der Bibliographie sowie einen Anhang mit einer Einführung in die Architektur des Werkes in seinem wissenslogischen Aufbau als Ausarbeitung seines „Tree of Science Modells“ (2007).This archive contains the complete bibliography of the author and some texts about H. G. Petzold, moreover an epilogue with an introduction to the architecture of the works in its epistemological structure and composition and as an elaborations of Petzold’s „Tree of Science Modell (2007).https://www.fpi-publikation.de/polyloge/01-2009-petzold-h-g-gesamtbibliographie-h-g-petzold-1958-2009-updating-november2009/peerReviewedpublishedVersio
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Vaccination of Cows with a Combined Rotavirus/Enterotoxigenic "E. Coli" K99 Vaccine to Protect Newborn Calves Against Diarrhoea
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3346: Samuel G. Freedman, author, 2013
Photograph of author Samuel G. Freedman, at NT Daily Slash meeting in the Mayborn School of Journalism at UNT
Use of the Keystone perforator Island flap in the treatment of chronic lower extremity wounds complicated by osteomyelitis
Introduction: Reconstruction of chronic lower extremity wounds can be especially challenging when these wounds are complicated by osteomyelitis. They require the joint expertise of plastic and orthopaedic surgeons. Methods: We report our experience using the Keystone Perforator Island Flap following wound and bone debridement as a valuable surgical tool for coverage of complex wounds with bone infection. Results: Twelve patients underwent similar procedures with overall good outcomes, although two patients experienced a complication, specifically partial flap necrosis and wound dehiscence subsequent to recurrent osteomyelitis. We also reviewed the underlying physiological mechanisms of employing the Keystone flap in order to demonstrate its advantages and efficacy. Conclusion: Our results confirm that the Keystone flap can be a safe, reliable and effective method for coverage of soft tissue defects and the preservation of bone integrity in the management of patients with chronic osteomyelitis
The Right to Strike under the United States Constitution: Theory, Practice, and Possible Implications for Canada
Answering critics of the Canadian Supreme Court's judgment in B.C. Health, the author argues that the Court laid the foundation for a principled and durable doctrine protecting constitutional labour rights, one that goes directly to the heart of the matter — the inequality of workers’ power in the employment relation. In the author’s view, two paths could lead from B.C. Health to the recognition of Charter protec- tion for a right to strike: one that treats the right as an accessory to col- lective bargaining, and one that upholds the right directly on the basis of the Charter values of equality and participation. The author supports the latter approach, contending that constitutional rights should be defined in relation to fundamental values, in a way that is not contingent on time-bound or fact-sensitive assessments about the role of strikes within a particular collective bargaining regime. Although a Charter right to strike may involve the courts in difficult choices about when to defer to legislative policy decisions, and courts may lack the institutional capac- ity to deal effectively with labour law issues, the author points out that judges can look to ILO standards for expert guidance. Noting that the U.S. experience in this area might be of considerable use to Canadians, the author concludes by providing an overview of American case law concerning a constitutional right to strike.Peer reviewe
G-Rank: Unsupervised Continuous Learn-to-Rank for Edge Devices in a P2P Network
Ranking algorithms in traditional search engines are powered by enormous training data sets that are meticulously engineered and curated by a centralized entity. Decentralized peer-to-peer (p2p) networks such as torrenting applications and Web3 protocols deliberately eschew centralized databases and computational architectures when designing services and features. As such, robust search-and-rank algorithms designed for such domains must be engineered specifically for decentralized networks, and must be lightweight enough to operate on consumer-grade personal devices such as a smartphone or laptop computer. We introduce G-Rank, an unsupervised ranking algorithm designed exclusively for decentralized networks. We demonstrate that accurate, relevant ranking results can be achieved in fully decentralized networks without any centralized data aggregation, feature engineering, or model training. Furthermore, we show that such results are obtainable with minimal data preprocessing and computational overhead, and can still return highly relevant results even when a user’s device is disconnected from the network. G-Rank is highly modular in design, is not limited to categorical data, and can be implemented in a variety of domains with minimal modification. The results herein show that unsupervised ranking models designed for decentralized p2p networks are not only viable, but worthy of further research.https://github.com/awrgold/G-RankComputer Scienc
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