1,720,956 research outputs found
Extraction of fractions enriched in bioactive compounds from aqueous extracts of Sargassum muticum
No full textLas algas pardas son una fuente biorrenovable de compuestos bioactivos de interés en las industrias alimentaria, cosmética y farmacéutica. En este trabajo se emplearán tecnologías de bajo impacto ambiental y disolventes verdes para la obtención de fracciones activas. Se llevará a cabo el fraccionamiento y posterior identificación de los compuestos más activos en ensayos de actividad antioxidante y antitumoral.As algas pardas son unha fonte biorrenovable de compostos bioactivos de interese nas industrias alimentaria, cosmética e farmacéutica. Neste traballo empregaranse tecnoloxías de baixo impacto ambiental e disolventes verdes para a obtención de fraccións activas. Levarase a cabo o fraccionamento dos compostos que resulten mais activos en ensaios de actividade antioxidante e antitumoral.Brown algae are a bio-renewable source of bioactive compounds of interest in food, cosmetic and pharmaceutical industries. In this work, low environmental impact technologies and green solvents to obtain active fractions were used. Fractionation of the most active compounds in test of antioxidant and antitumor activity will be studied
Valorización do alga invasora "Sargassum muticum" Yendo (Fensholt) mediante a obtención de fraccións activas para uso cosmético e farmacéutico
Full text linkThe present PhD thesis shows a proposal of valorization of the invasive alga "S. muticum" including several processes to obtain and purify bioactive compounds and some of their applications.
Extraction and fractionation steps have been tested and optimized, the obtained fractions and compounds were characterized and their potential as cosmetic and pharmaceutical ingredients were determined. Utilized processes and obtained streams were integrated and connected under the biorefinery concept, due to minimize the waste production, maximize subproducts advantage and increase the yield of high-added value products. In addition, the colaboration with other research centers by short-term researchs or work colaboration, a compound was isolated and its structure was elucidated. Obtained compound, extracts and fractions were tested in vitro for photodamage attenuation capacity in UVA irradiated dermal cells, for anti-tumoral capacity in cancer cells, and as antioxidant agents in cosmetics formulations stability assays.
There are some works describing the use of different components of the algal biomass and, probably, there are still new applications to discover in cosmetics and pharmaceutics. Several studies are needed to complete and make progresses on this proposal of S. muticum valorization.Se pretende desarrollar un proceso de fraccionamiento del algas invasoras, en particular de una de las más peligrosas desde el punto de vista ecológico y económico, "Sargassum muticum", para aprovechar componentes útiles como ingredientes cosméticos con actividad antioxidante. El aprovechamiento integral supone una aproximación práctica a la producción sostenible y la gestión racional de recursos naturales, reduciendo el impacto ecológico y económico negativo de estas algas y minimizando la generación de residuos.
Se realizará la optimización de los procesos de extracción, concentración y purificación de antioxidantes y su evaluación para empleo cosmético. Se plantea la extracción sucesiva de componentes del citoplasma y de la pared celular (alginatos, fucoidanos, florotaninos) con diversas tecnologías y su purificación posterior. Se abordará la caracterización físico-química y evaluación de propiedades toxicológicas, biológicas y tecnológicas de diversas fracciones para la formulación de cosméticos modelo, cuya estabilidad oxidativa se evaluará durante el almacenamiento.
Se incluye el análisis comparativo de diferentes alternativas, una estimación preliminar de mercado de los productos obtenidos y el análisis económico del proceso propuesto. Se pretende que la tecnología desarrollada sea además aplicable al procesamiento de otras algas invasoras y/o a fracciones de desecho de algas alimentarias.Preténdese desenvolver un proceso de fraccionamento de algas invasoras, en particular das más perigosas dende o punto de vista ecolóxico e económico, "Sargassum muticum", para aproveitar os compoñentes útiles como ingredientes cosméticos con actividade antioxidante. O aproveitamento integral supón unha aproximación práctica á producción sostible e a xestión racional dos recursos naturais, coa reducción do impacto ecolóxico e económico negativo destas algas e a minimización da xeración de residuos.
Realizarase a optimización dos procesos de extracción, concentración e purificación de antioxidantes e a súa evaluación para o empleo cosmético. Plantésaxe a extracción sucesiva de compoñentes do citoplasma e da parede celular (alxinatos, fucoidanos, florotaninos) con diversas tecnoloxías e a súa purificación posterior. Abordarase a caracterización físico-química e a evaluación de propiedades toxicolóxicas, biolóxicas e tecnolóxicas de diversas fraccións para a formulación de cosméticos modelo, das que se evaluará a súa estabilidade oxidativa durante o almacenamento.
Inclúese a análise comparativa de diferentes alternativas, unha estimación preliminar de mercado dos productos obtidos e a análise económica do proceso proposto. Preténdese que a tecnoloxía desenvolvida sexa, ademais, aplicable ó procesamento de outras algas invasoras e/ou ás fraccións de desfeito das algas alimentarias.Ministerio de Educación y Ciencia | Ref. BES 2010-041807Ministerio de Economía y Competitividad | Ref. CTM 2012-3809
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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