1,172 research outputs found
sj-docx-1-aut-10.1177_13623613211050751 – Supplemental material for Adaptation and validation of two autism-related measures of skills and quality of life in Ethiopia
Supplemental material, sj-docx-1-aut-10.1177_13623613211050751 for Adaptation and validation of two autism-related measures of skills and quality of life in Ethiopia by Anton Borissov, Ioannis Bakolis, Bethlehem Tekola, Mersha Kinfe, Caterina Ceccarelli, Fikirte Girma, Rehana Abdurahman, Tigist Zerihun, Charlotte Hanlon and Rosa A Hoekstra in Autism</p
A Modular Logic Approach for Expressing Web Services in XML Applying Dynamic Rules in XML
RuleML is considered to be a markup language for the semantic web. It allows the enrichment of web ontologies by adding definitions of derived concepts and it enhances interoperability among different systems and tools by publishing rules in an XML format. Moreover the in-creasing demand for interfaces that enhance information sharing has given rise to XML doc-uments that include embedded calls to web services. In this paper we propose a variation of RuleML that is based on modular logic programming. Our approach is based in a two level architecture. In the first level a modular logic language, called M-log, is presented. This lan-guage encompasses several mechanisms for invoking web services. In the second level we ex-ploit the semantics of M-log to present a variation of RuleML with rich modeling capabilities. Formal foundations for this variation are given through direct translation to M-log semantics.Knowledge Management, XML, Modular Logic Programming, E-Services
Case management for integrated care of frail older people in community settings
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effectiveness of case management for integrated care of frail older people compared to usual care
Ioannis Dallaei De imaginibus libri IV.
Includes errata at end.Signatures: *⁸ A-2L⁸ 2M⁴ chi².Woodcut printer's device on t.p. Head- and tail-pieces, initials.Scanned copy bound with: Joannis Dallaei Apologia pro ecclesiis reformatis. Amstelodami : Apud Jodocum Jansonium, 1652.Mode of access: Internet.Binding: vellum. Author & titles written at head of spine.With his: Apologia pro ecclesiis reformatis (Amsterdam : J. Janson, 1652)
Development and validation of the DISCUS scale: a reliable short measure for assessing experienced discrimination in people with mental health problems on a global level
BACKGROUND: The Discrimination and Stigma Scale (DISC-12) was specifically developed to measure experienced and anticipated discrimination reported by people with mental health problems. However, the length of the DISC-12 may represent a disadvantage especially in country settings with limited human capacity and infrastructure. The purpose of the study was to develop a short version of DISC-12 (DISCUS) to address these limitations. METHODS: Data from 1087 participants with major depressive disorder and 732 patients with schizophrenia were collected as part of two research network studies across 35 countries - Anti Stigma Programme European Network (ASPEN) and International Study of Discrimination and Stigma (INDIGO). We used a Meta Exploratory Factor Analysis (meta-EFA) and a Multiple Causes Multiple Indicators (MIMIC) Model to reduce the number of items in the DISC-12 scale. The validity and reliability of the reduced scale (DISCUS) was tested in 202 people with the full spectrum of mental disorders recruited in a cross-sectional study conducted in South London. Psychometric validation for the reduced scale used confirmatory factor analysis and measures of Cronbach's alpha and Pearson's correlation coefficient. RESULTS: meta-EFA reduced twenty-one items to twelve items. An additional item was discarded with the use of the MIMIC model. The 11-item DISCUS demonstrated excellent reliability (Cronbach's alpha >0.85), good fit (Tucker Lewis Index and Comparative Fit Index value>0.9) and weak to moderate construct validity. CONCLUSIONS: The DISCUS scale is a consistent and valid instrument to measure experienced and anticipated discrimination predominantly in personal and social relationships in global settings
A feasibility hybrid II randomised controlled trial of volunteer ‘Health Champions’ supporting people with serious mental illness manage their physical health: study protocol
Background People with serious mental illnesses (SMI) such as schizophrenia often also have physical health illnesses and interventions are needed to address the resultant multimorbidity and reduced life expectancy. Research has shown that volunteers can support people with SMI. This protocol describes a feasibility randomised controlled trial (RCT) of a novel intervention involving volunteer ‘Health Champions’ supporting people with SMI to manage and improve their physical health. Methods This is a feasibility hybrid II randomised effectiveness-implementation controlled trial. The intervention involves training volunteers to be ‘Health Champions’ to support individual people with SMI using mental health services. This face-to-face or remote support will take place weekly and last for up to 9 months following initial introduction. This study will recruit 120 participants to compare Health Champions to treatment as usual for people with SMI using secondary community mental health services in South London, UK. We will measure the clinical and cost effectiveness including quality of life. We will measure the implementation outcomes of acceptability, feasibility, appropriateness, fidelity, barriers and enablers, unintended consequences, adoption and sustainability. Discussion There is a need for interventions to support people with SMI with their physical health. If this feasibility trial is successful, a definitive trial will follow to fully evaluate the clinical, cost and implementation effectiveness of Health Champions supporting people with SMI
Development and rapid evaluation of services to support the physical health of people using psychiatric inpatient units during the COVID-19 pandemic: study protocol
Background: people diagnosed with a serious mental illness have worse physical health and lower life expectancy than the general population. Integration of mental and physical health services is seen as one service development that could better support this. This protocol describes the evaluation of the provision of a Virtual Physical Health Clinic (VPHC) and Consultant Connect (CC) services to one UK-based mental health Trust.Methods: prospective, formative, pragmatic evaluation using both quantitative and qualitative techniques and driven by implementation science theoretical frameworks. The VPHC and CC are described along with the methodology being used to rapidly evaluate their implementation, effectiveness and potential economic impact in order to inform future roll out. We will assess the implementation process through quantitative data on uptake and reach and through self-reported data to be collected from interviews and the use of validated implementation outcome assessment measures. We will assess implementation strategies using the Expert Recommendations for Implementing Change (ERIC) strategies as a framework. We will assess the health economic impact of both services using established health economic methods including cost comparison scenarios and health service utilisation analyses.Discussion: supporting the physical health management of people in psychiatric inpatient units is important in improving the physical health of this population. Integration of mental and physical health can help this to happen effectively. This initiative provides one of the first service evaluation protocols of its kind to be reported in the UK at the time of the COVID-19 pandemic
Ioannis Metaxas: Speech on the occasion of the inauguration of public works
Title: Λόγος κατά τα εγκαίνια των έργων του Σελινούντος Αιγιαλείας (Speech on the occasion of the inauguration of the public works at Selinous, Egialia) Originally published: Delivered at Selinous on 31 October 1937. Language: Greek The excerpts used are from Ioannis Metaxas, Λόγοι και Ομιλίες (Athens: Ερμής, 1992), pp. 247–255. About the author Ioannis Metaxas [1871, Ithaca (Ionian Islands)–1941, Athens]: military officer and politician. He was born into a well-known aristocratic family. In ..
The use of dietary patterns empirically derived from principal components analysis and alternative strategies to identify associations between diet and disease
Dietary patterns derived empirically using principal components analysis (PCA) are widely employed for investigating diet-disease relationships. The aim of the study was to investigate whether PCA performed better at identifying associations between diet and disease than analysing each food on the FFQ separately, a process we refer to as exhaustive single food analysis (ESFA).
A systematic review of nutritional epidemiology literature relating to the use of PCA in identifying dietary patterns in observational and cohort studies from 2004-2009 was employed. Furthermore, we simulated diet and disease data using real food frequency questionnaire data and assuming that a number of foods or dietary pattern intakes were causally associated with disease. In each simulation, ESFA and PCA were employed to identify foods associated with disease using logistic regression, allowing for multiple testing and adjusting for energy intake. ESFA was further adjusted for principal components, foods which were significant in unadjusted ESFA, and propensity scores. For each method, we investigated the power, with which we could identify an association between diet and disease, and the power and false discovery rate (FDR) for identifying associations with specific food intakes. We apply our innovative methodology to a real dietary dataset (GA2LEN survey).
ESFA had greater power to detect an association of diet with disease than PCA, and greater power and lower FDR for identifying associations with specific foods. FDR increased with increasing sample size using both methods. However, when ESFA was adjusted for foods that were significant in unadjusted ESFA, FDRs were controlled successfully at the desired level of 20%.
Our results raise questions about the use of PCA in nutritional epidemiology. Adjusted ESFA identifies foods that are causally linked to disease with a low rate of false discoveries, and surprisingly good power. These findings were not fully supported from the analysis of the GA2LEN data-set
Literary Recants of a Tenth-Century Scholar: The Case of Ioannis Kaminiates
This paper seeks to interpret the attitude of Ioannis Kaminiates towards Homer, for while initially criticising his literary predecessor, the author of On the Capture of Thessaloniki later adopts many of his turns of phrase
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