170,042 research outputs found
Il Movimento di Studi per l'Architettura 1945-1961
No full textIl volume, attraverso l'attività e i documenti del Msa, restituisce e interpreta il complesso dibattito sull'architettura e la ricostruzione nella Milano del secondo dopoguerra
Imaging Ferromagnetic Tracers With An Ac Biosusceptometer
No full textThe aim of this work was to study the feasibility of obtaining images of the distribution of ferromagnetic tracers using an ac biosusceptometer (ACB). The images were generated by mapping the response of the ACB at short distances due to the presence of a ferrite powder dispersed in a planar gel matrix with different shapes. The ACB was scanned over the sample and the voltages generated by the variation in ferrite concentration were sampled. Methods to render and image the distribution of ferromagnetic particles were studied. The generalized Wiener parametric method gave the best results. The system has a potential to be used in functional images of the gastrointestinal tract where a moderate resolution is required. We conclude that this biomagnetic method can be successfully used to generate planar functional images of magnetic particles in the near field. © 2000 American Institute of Physics.71625322538Erol, R.A., Cherian, P., Smallwood, R.H., Brown, B.H., Bardhan, K.D., (1996) Physiol. Meas., 17, pp. A141Ikeya, M., Ishii, H., (1990) J. Magn. Reson., 88, p. 130Smith, C.M., Stevens, A.D., (1994) Br. J. Radiol., 67, p. 1186Roth, B.J., Sepulveda, N.G., Wikswo J.P., Jr., (1989) J. Appl. Phys., 65, p. 361Moreira, M., Murta, L.O., Baffa, O., (1994) Phys. Med. Biol., 39 A, p. 633Miranda, J.R.A., Baffa, O., Oliveira, R.B., Matsuda, N.M., (1992) Med. Phys., 19, p. 445Baffa, O., Oliveira, R.B., Miranda, J.R., Troncon, L.E.A., (1995) Med. Biol. Eng. Comput., 33, p. 353Oliveira, R.B., Baffa, O., Troncon, L.E.A., Miranda, J.R.A., Cambrea, C.R., (1996) Eur. J. Gastroent. Hepatol., 8, p. 491Miranda, J.R.A., Oliveira, R.B., Sousa, P.L., Braga, F.J.H., Baffa, O., (1997) Phys. Med. Biol., 42, p. 1791Daghastanli, N.A., Braga, F.J.H.N., Oliveira, R.B., Baffa, O., (1998) Physiol. Meas., 19, p. 413Forsman, M., Hultin, L., Abrahamsson, H., (1995) Biomagnetism: Fundamental Research and Clinical Applications. Studies in Applied Electromagnetics and Mechanics, 7, p. 739. , edited by C. Baumgartner, L. Deecke, G. Stroink, and S. J. Williamson Elsevier, AmsterdamBasile, M., Neri, M., Carriero, A., Casciardi, S., Comani, S., Del Gratta, C., Donate, L.G., Romani, G.L., (1992) Dig. Dis. Scie., 37, p. 1537Bruno, A.C., (1997) J. Appl. Phys., 82, p. 1Cruvinel, P.E., Cesareo, R., Crestana, S., Mascarenhas, S., (1990) IEEE Trans. Instrum. Meas., 39, p. 745Lim, J.S., (1990) Two-Dimensional Signal and Image Processing, , Prentice-Hall, Englewood Cliffs, NJJ. P. Wikswo, Jr., N. G. Sepulveda, and I. M. Thomas, Ref. 11, p. 789Tan, S., Ma, Y.P., Smith, I.M., Wikswo J.P., Jr., (1996) IEEE Trans. Magn., 32, p. 230Weber, E., (1951) Electromagnetic Fields: Theory and Applications, Mapping of Magnetic Fields, 1. , Wiley, New YorkSpiegel, M.R., (1990) Mathematical Handbook of Formulas and Tables, , McGraw-Hill, New YorkBruno, A.C., Costa Ribeiro, P., Von Der Wied, J.P., Symko, O., (1986) J. Appl. Phys., 59, p. 2584Vrba, J., Fife, A.A., Burbank, M., Weinberg, H., Bricket, P.A., (1982) Can. J. Phys., 60, p. 106
Contact imidazole activity against resistant bacteria and fungi
No full textThe activities of miconazole and miconazole sulphosalicylate were evaluated by a contact test using strains of Enterococcus faecalis and Escherichia coli and Candida spp selected for their resistance. The results showed that killing of the organisms occured within a few minutes. Imidazole activity required a medium of low electrical conductivity and a pH of 5.6. Greater sensitivity could be obtained with pretreatment of the microbial suspensions with sodium dioctylsulphosuccinate. Microorganisms tested in culture media with low electrical conductivity and at pH 5.6 showed enhanced sensitivity to azoles with MIC values about 20-30 times lower than those obtained using control media. Practical implications of the use of topical drugs are discussed. (C) 2001 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Single-incision laparoscopic adnexectomy in an obese patient with previous laparotomies
No full textNo case of single-incision laparoscopic surgery in obese patients who had previously undergone multiple midline vertical laparotomies has been described in the literature to date. Hence we report the first case of single-port laparoscopic salpingo-oophorectomy in an obese patient who was affected by a left adnexal mass and who had previously undergone 3 midline vertical laparotomies
Molecular genetics of bladder cancer: Targets for diagnosis and therapy
No full textTransitional cell carcinoma of the bladder is a common tumor. While most patients presenting superficial disease can be expected to do well following treatment, still many patients will return to our office with muscle invasive and metastatic disease. Survival in advanced bladder cancer is less than 50%. Tumors of similar histologic grade and stage have variable behavior, suggesting that genetic alterations must be present to explain the diverse behavior of bladder cancer. It is hoped that through the study of the subtle genetic alterations in bladder cancer, important prognostic and therapeutic targets can be exploited. Many new diagnostic tests and gene therapy approaches rely on the identification and targeting of these unique genetic alterations. A review of literature published on the molecular genetics of bladder cancer from 1970 to the present was conducted. A variety of molecular genetic alterations have been identified in bladder cancer. Oncogenes (H-ras, erbB-2, EGFR, MDM2, C-MYC, CCND1), tumor suppressor genes (p53, Rb, p21, p27/KIP1, p16, PTEN, STK15, FHIT, FEZI/LZTS1, bc10), telomerase, and methylation have all been studied in bladder cancer. Several have proven to be potentially useful clinical targets in the prognosis and therapy of bladder cancer such as staining for p53 and gene therapy strategies such as p53 and fezl. Clinical trials targeting HER2/neu and the EGFR pathways are underway. The UroVysion bladder cancer assay relies on FISH to detect genetic alterations in this disease. Continuing identification of the molecular genetic alterations in bladder cancer will enhance future diagnostic and therapeutic approaches to bladder cancer. Capitalizing on these alterations will allow early detection, providing important prognostic information and unique targets for gene therapy and other therapeutic approaches
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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