1,720,994 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Cardiovascular changes induced by antitumoral treatment in non-Hodgkin lymphomas
No full textActualitatea și importanța problemei abordate.
Bolile cardiovasculare reprezintă una dintre principalele cauze de mortalitate în rândul
pacienților diagnosticați cu diferite tipuri de malignități. Studiile recente sugerează faptul că cele mai
accentuate dinamici ale riscului cardiovascular sunt observate în primul an de la stabilirea
diagnosticului de proces tumoral [1]. Deși majoritatea pacienților cu maladie tumorală decedează din
cauza bolii în sine, complicațiile cardiovasculare reprezintă a doua cauză de mortalitate [2]. Acest
fenomen este descris și în cadrul derulării tratamentului limfoamelor non-Hodgkin (LNH). Totuși,
înțelegerea și detectarea timpurie a complicațiilor cardiovasculare în terapia LNH rămâne o provocare
nerezolvată [3]. [...]Relevance and importance of the addressed issue
Cardiovascular diseases represent one of the leading causes of mortality among patients diagnosed with various types of malignancies. Recent studies suggest that the most significant changes in cardiovascular risk occur within the first year following the diagnosis of a malignant disease [1]. Although the majority of cancer patients ultimately die from the malignancy itself, cardiovascular complications represent the second most common cause of death [2]. This phenomenon has also been observed during the treatment of non-Hodgkin lymphomas (NHL). Nevertheless, the understanding and early detection of cardiovascular complications in NHL therapy remain unresolved challenges [3]. [...
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
The role of cardiovascular risk factors in patients with rheumatic heart diseases
Full text linkState University of Medicine and Pharmacy "Nicolae Testemiţanu”, Chişinău, Republic of MoldovaIntroduction: Rheumatic heart diseases lead to chronic heart failure and reduced quality of
life in many patients. Ischemic heart disease represents the major role in the structure of morbidity
and mortality worldwide. Traditional risk factors for vascular disease are important in, but do not
fully account for, the increased risk of ischemic heart disease in population.
Purpose and Objectives: To evaluate cardiovascular risk factors and appreciate the risk of
cardiovascular death in patients with rheumatic heart diseases.
Materials and Methods: We examined a sample of 65 patients with rheumatic heart diseases
according to the diagnostic criteria. We applied the SCORE scale and divided the sample into two
groups. The first one with SCORE 5% (35
patients). We assessed traditional and novel risk factors of cardiovascular diseases by clinical and
laboratory methods, and made a comparative analysis of modern risk factors.
Results: The study group included 26 men (40%) and 39 women (60%) with mean age 59.5 +
0.03. In the study group predominated mitral valvulopathy in 46 (70.7%) patients vs. 19 (29.2%)
patients with aortal one. From the traditional risk factors the most significant ones for the increased
cardiovascular risk were outlined by hypertension in 22 (62.9%) cases, followed by dyslipidemia —
19 (54.3%) cases and obesity - 10 (28.6%) cases. From modern risk factors a major role had the left
ventricular hypertrophy assessed on ECG which was found mainly in patients with SCORE > 5% —
10 (28.6%) patients vs. 6 (20%) patients with SCORE 5%
had a higher prevalence of other modern risk factors, such as: metabolic syndrome, a high CRP
level, a low glomerular filtration rate, and a high level o f anxiety determined by using Spilbenger
test. On the other hand, the patients with SCORE < 5% were appreciated mainly with concentric
hypertrophy, in 7 (23.3%) cases vs 5 (14.3%) cases in patients with SCORE > 5%. Therefore, the
concentric hypertrophy is considered being a negative factor for the cardiovascular events.
Conclusion: Patients with rheumatic heart diseases have an increased cardiovascular risk,
influenced not only by traditional risk factors, but also by the modern ones
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Palliative care for a patient with heart failure
Full text linkDepartment of Internal
Medicine, Cardiology, Nicolae Testemitanu State University of Medicine and Pharmacy,
Chisinau, Republic of Moldova, The 8th International Medical Congress for Students and Young Doctors, September 24-26, 2020Background. Despite growing need for palliative care for patients with advanced heart failure,
many challenges exist to making effective palliative care interventions available. Little data
exists on heart failure patients who receive palliative care, and there are only a handful of
studies examining which palliative care interventions are effective in heart failure. Case report. We present a case of 50 years old man admitted at our department with signs of
advanced heart failure. Physical examination attested a severe peripheral edema, a tensionate
abdomen with an enlarged liver with a 75 heart beats/min with a arterial tension about 85/55
mmHg. His cardiac problems started at his 34 years old when multiple paroxysmal attacks of
atrial fibrillation were detected, sinus rhythm were assessed by multiple electrical
cardioversions (2002-2004). In 2004 was made a procedure of ablation near the paradisiac
region of right atrium. Next years (2011-2012) due to the progressive signs of heart failure and
atrial asystole detected at ECG-Holter monitoring accompanied by severe bradycardia, a
permanent pacemaker was implanted in VVIR pacing mode. In parallel his echocardiogram
showed normal dimensions of left and right ventricles, but a progressive severe enlargement of
both atrial chambers with a progressive worsening of mitral and tricuspid regurgitation,
ejection fraction of left ventricle was about 30-35%, severe pulmonary hypertension. In 2013
was made an annuloplasty of mitral and tricuspid valves. Also due to instability of heart rhythm
and uncontrolled heart rate, the pacing mode was switched to AAIR mode, then to DDDR, and
then again to VVIR pacing modes. At the moment of presentation his echocardiogram showed
a severe dilatation of right and left atrial chambers, right ventricle, a mild enlargement of left
ventricle, with a severe diffuse reduction in ejection fraction (12%), a mild to moderate mitral
and tricuspid regurgitation and a severe pulmonary hypertension. Coronary angiogram showed
non-obstructive coronary lesions. His medical treatment consisted of standard medication of
heart failure, intensive diuresis, medication of pain and antidepressants. Interventional
treatment included a few sessions of thoracocentesis, decompression of thoracic lymphatic
duct, drainage of ascetic fluid and peritoneal lavage.
Conclusions. In the setting of echocardiographic data of the presented patient and arrhythmic
events it’s hard to make a differential diagnosis between tachycardia-mediated cardiomyopathy
and dilated cardiomyopathy. Prognosis of such case is uncertain and the difference between
curative and palliative treatment is not well defined. But, still, the emerging role of palliative
care is drived from improving quality of life for patients with end-stage congestive heart failure
Cardiovascular changes induced by antitumoral treatment in non-Hodgkin lymphomas. Summary of the PhD thesis in medical sciences: 321.03 – Cardiology
No full textRelevance and importance of the addressed issue.
Cardiovascular diseases represent one of the leading causes of mortality among patients diagnosed with various types of malignancies. Recent studies suggest that the most significant changes in cardiovascular risk occur within the first year following the diagnosis of a malignant disease [1]. Although the majority of cancer patients ultimately die from the malignancy itself, cardiovascular complications represent the second most common cause of death [2]. This phenomenon has also been observed during the treatment of non-Hodgkin lymphomas (NHL). Nevertheless, the understanding and early detection of cardiovascular complications in NHL therapy remain unresolved challenges [3].
Non-Hodgkin lymphomas (NHL) are malignant tumors that originate from lymphoid tissue and are characterized by genetic, clinical, therapeutic, and prognostic heterogeneity. NHL encompasses a wide spectrum of clinical behavior, ranging from indolent to highly aggressive forms of the disease [4]. These lymphomas are among the most common hematologic malignancies, accounting for approximately 3.1–4.3% of all malignant tumors [5]. In the Republic of Moldova, the diagnosis of NHL is established at advanced stages of the disease in the majority of patients (87%) [6]. The 5-year survival rate has shown a significant increase, from 46% in 1975 to 72.7% during the 2010–2016 period. This improvement is largely attributed to the introduction and application of novel chemotherapeutic regimens and agents [7]. Currently, therapeutic options involve complex combinations of immunotherapy, chemotherapeutic agents, and radiotherapy. As a result of these treatments, many cancer survivors face an increased risk of developing cardiovascular complications [8]. Understanding the various cardiovascular adverse effects associated with NHL therapy is essential for their effective prevention and appropriate management. The severity of cardiotoxicity is influenced by several factors, including the mechanism of action of the specific therapeutic agents used, the initial and cumulative doses, the route of administration, the presence of cardiovascular risk factors, genetic predisposition, and the patient's age [9]. Antitumor therapy-related adverse cardiovascular effects may occur either acutely during treatment or may manifest months or even years after its completion. Among the most common cardiovascular complications associated with NHL treatment are cancer therapy-related cardiac dysfunction—which may range from asymptomatic forms to overt heart failure—arterial hypertension, venous thromboembolism, arrhythmias, and pericardial disorders [10]. [...
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