103,951 research outputs found
Data and code for Scale-invariant random geometry from mating of trees: a numerical study
No full textThis entry contains the source code, simulation data and data analysis notebooks for the paper
T. Budd, A. Castro, "Scale-invariant random geometry from mating of trees: a numerical study." arXiv:2207.05355.
This work is part of START-UP 2018 programme with project number 740.018.017, which is financed by the Dutch Research Council (NWO)
Domination and resistance in Herman Mel Ville´s characters
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e ExpressãoA produção literária de Herman Melville é caracterizada por disputas de poder nas quais forças de dominação enfrentam resistência. Este é o caso dos contos "Billy Budd, Marinheiro", "Benito Cereno" e "Bartlety, O Escrivão". "Billy Budd, Marinheiro" enfoca resistência ao poder militar. Em "Benito Cereno", as relações de poder acontecem entre escravos e senhores. "Bartleby, O Escrivão" pode ser entendido com um caso de resistência civil ao poder econômico. As interações presentes nestes contos sugerem que o poder é um instrumento positivo na vida social uma vez que toda força de dominação gera resistência. Resistência, por sua vez, não permite que o poder absoluto se instale, questionando, e por vezes, mudando situações sociai
Marriage record of Edwards, George W. and Budd, Mamie L.
No full textMarriage license for George W. Edwards and Mamie L. Budd. T. Tyrrell was the officiant
An introduction to Object Oriented programming
No full textIn An Introduction to Object-Oriented Programming, Timothy Budd provides a language-independent presentation of object-oriented principles, such as objects, methods, inheritance (including multiple inheritance) and polymorphism. Examples are drawn from several different languages, including (among others) C++, C#, Java, CLOS, Delphi, Eiffel, Objective-C and Smalltalk. By examining many languages, the reader is better able to appreciate the general principles that lie beyond the syntax of the individual languages
Stress Variations with Ice Flow Over Undulations
No full textAbstractThe analysis of steady-state flow over bedrock perturbations of Budd(1970[a]) is extended to evaluate the stress variations associated with the flow. In particular the four separate terms of the fundamental one-dimensional (longitudinal) stress equation (Budd,1968) are examined to show explicitly how the longitudinal stress gradient G, the base stress τ, the surface slope stress s, and the integrated second derivative of the shear stress T all vary over-a given wave.The result shows an error of a factor of 2 in some earlier studies relating longitudinal stress variations to the slope. This error resulted from the erroneous assumption that remains constant at its regional value. In fact the basal stress varies over the undulations in a similar way to the longitudinal stress gradient, and this is the same as the surface slope stress for long waves, but for short waves or less) requires the addition of the fourth term T, which then becomes dominant.</jats:p
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Environmentally Sustainable Air Transport: A Focus on Airline Productivity
No full textTackling air transport’s environmental externalities represents one of the
key challenges facing the industry. Airlines, airport operators, aircraft
manufacturers, air navigation service providers, and regulators are
increasingly coming to the realization that environmental impacts are key
constraints on growth, and that sound environmental and commercial
business practices are not necessarily mutually exclusive.
Like many other sectors, the framing of environmental protection
measures in air transport is generally couched in terms of conforming
to the guiding principles of sustainability, which is the long-held idea of policies balancing environmental, social, and economic priorities in
a way that meets the needs of present-day societies without jeopardizing
the ability of future societies to do likewise. Sustainable practices are
considered to be those that reduce or limit the environmental impacts of
a process or practice, while at the same time creating financial benefits
and social opportunities. Collectively, these aspects of sustainability are
known as the ‘triple bottom line’ (see Fig. 1).
While the environmental impacts of aviation have long been understood
(see Lee et al. 2009), political debates surrounding aviation’s
impact on the environment remain contested and contentious. Such
debates are relevant in a global context due largely to the significant predicted
near-to-medium-term growth in the global air transport market
and the knock-on impacts this will have in terms of the environment.
ICAO (International Civil Aviation Organization) forecasts a near tripling
of the global commercial aircraft fleet, rising from just under
20,000 aircraft in 2010 to 56,500 in 2040, with accompanying increases
in the passenger and air cargo markets (ICAO 2016). Concurrently,
international aviation CO2 emissions are forecasted to grow, under the
‘baseline growth scenario including fleet renewal, from around 500 Mt
in 2010 to nearly 2000 Mt in 2040’ (ICAO 2016). Our work aims to build on this important area of research by estimating
the trend in airline productivity when considering both the economic
and environmental aspects of air transport. We apply a data envelopment
analysis based on the productivity index to estimate the economic evolution
of the major global airlines. More precisely, we adopt a biennial
Malmquist–Luenberger index (BML), which is an indicator of productivity
that changes over time
Budd-Chiari syndrome in a 25-year-old woman with Behçet's disease: a case report and review of the literature
No full textAbstract Introduction The risk that patients with Behçet's disease will develop thrombotic complications has been previously described. Although it is distributed worldwide, Behçet's disease is rare in the Americas and Europe. Even though the pathogenic mechanisms of vascular complications of Budd-Chiari syndrome in patients with Behçet's disease are unknown, severe vascular complications of Budd-Chiari syndrome associated with Behçet's disease seem to affect mainly young men. Case presentation We report a case of Budd-Chiari syndrome, a severe vascular complication that developed in a 25-year-old Afro-Brazilian woman with Behçet's disease. Conclusion Severe vascular complications of Budd-Chiari syndrome in patients with Behçet's disease are much more common in young adult male patients; we present a rare case of Budd-Chiari syndrome in a young Afro-Brazilian woman with Behçet's disease.</p
The challenges of clinical trials for adolescents and young adults with cancer.
No full textIn the United States, Europe, and Australia, and probably all countries of the world, older adolescents and young adults with cancer are under-represented in clinical trials of therapies that could improve their outcome. Simultaneously, the survival and mortality rates in these patients have mirrored the clinical trial accrual pattern, with little improvement compared with younger and older patients. This suggests that the relative lack of participation of adolescent and young adult patients in clinical trials has lessened their chances for as good an outcome as that enjoyed by patients in other age groups. Thus, increased availability of and participation in clinical trials is of paramount important if the current deficits in outcome in young adults and older adolescents are to be eliminated. Regardless of whether there is a causal relationship, the impact of low clinical trial activity on furthering our scientific knowledge and management of cancer during adolescence and early adulthood is detrimental
Alteration of the MDM2-p73-P14ARF pathway related to tumour progression during urinary bladder carcinogenesis
No full textTransitional cell carcinomas (TCC) of the urinary bladder develop by a multistep process characterized by various stages of transformation differing in their grade of malignancy and biological behaviour. Since the prospective clinical outcome cannot be reliably predicted on histopathological grounds, we analysed the mRNA expression of the MDM2-p73-P14ARF tumour surveillance pathway in an attempt to detect alterations of gene activity, allowing a better understanding of the mechanisms responsible for conversion of low to high malignant TCC. Expression of the mRNA was determined in 71 TCC of various grades and stages using the real-time quantitative reverse transcription-polymerase chain reaction. The MDM2-p73-P14ARF pathway was dominated by the MDM2 gene, the mRNA expression of which proved to be significantly (5-fold) lower in advanced high-grade, high-stage than in superficial low-grade, low-stage TCC. Conversely, the expression of p73 mRNA increased with increasing tumour grades and stages, while the activity of the P14ARF gene was not substantially altered during early and late phases of urothelial carcinogenesis. Analysing the expression of spliced variants of MDM2 mRNA, we found a heterogeneous pattern including a novel splicing transcript coding for an abnormal protein. Promoter hypermethylation of P14ARF occurred in 10% of the TCC with an underexpression of mRNA. An analysis of the effects of lifestyle and occupational bladder cancer risk factors revealed that TCC of smokers showed a 2-fold elevated expression of MDM2 mRNA and an approximately 2-fold lower expression of P14ARF mRNA, whereas the activity of the p73 gene was unchanged. Heavy coffee consumption was associated with a 2-fold decreased expression level of P14ARF mRNA. Exposure to certain occupational hazards (plastic products, paints and lacquer, polycyclic hydrocarbons, chemical solvents) was observed to modulate the activity of the genes analysed. Our findings suggest that an alteration in the MDM2-p73-P14ARF pathway is involved in the progression of bladder cancer to a more malignant and aggressive form
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