169,872 research outputs found
Nuovi dati sull'assetto strutturale dell'area di Frontone (Appennino umbro-marchigiano). Carta geologico-strutturale.
No full textCarta Geologico-Strutturale
HLA-B27 negative ankylosing spondylitis and hidradenitis suppurativa: report of a case.
No full textThe association between hidradenitis suppurativa and joint involvement is well recognized. We describe a 63-year-old man with a severe HLA-B27 negative ankylosing spondylitis associated with hidradenitis suppurativa. We are not aware of any reports of such an association in the literature
Intraocular pressure in Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency
No full textPurpose: Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is one of the most common human genetic abnormalities, with a high prevalence in Sardinia, Italy, where the reported rates range from 10% to 15%. Hemizygous males have totally deficient erythrocytes. We are unaware of any previous report investigating intraocular pressure (IOP) in G6PD deficiency. The purpose of this study was to assess IOP in G6PD-deficient and G6PD-normal Sardinian men and ascertain whether there are significant differences between the two groups.
Methods: IOP was measured by applanation tonometry in 104 G6PD-deficient and 104 age-matched G6PD-normal men. The Student t test was used to assess differences in IOP values between the two groups.
Results: Mean IOP was 13.94 ± 2.62 mm Hg in G6PD-deficient men and 14.29 ± 2.84 mm Hg in G6PD-normal men, a not statistically significant result (P = 0.096).
Conclusions: Results suggest that men with G6PD deficiency do not have a higher risk of increased IOP
Metabolically healthy versus metabolically unhealthy obesity
No full textObesity-related disease complications reduce life quality and expectancy and increase health-care costs. Some studies have suggested that obesity not always entails metabolic abnormalities and increased risk of cardiometabolic complications. Because of the lack of universally accepted criteria to identify metabolically healthy obesity (MHO), its prevalence varies widely among studies. Moreover, the prognostic value of MHO is hotly debated, mainly because it likely shifts gradually towards metabolically unhealthy obesity (MUO). In this review, we outline the differential factors contributing to the metabolic heterogeneity of obesity by discussing the behavioral, genetic, phenotypical, and biological aspects associated with each of the two metabolic phenotypes (MHO and MUO) of obesity and their clinical implications. Particular emphasis will be laid on the role of adipose tissue biology and function, including genetic determinants of body fat distribution, depot-specific fat metabolism, adipose tissue plasticity and, particularly, adipogenesis. Finally, the emerging role of gut microbiota in obesity and adipose tissue dysfunction as well as the search for novel biomarkers for the obesity-related metabolic traits and associated diseases will be briefly presented. A better understanding of the main determinants of a healthy metabolic status in obesity would allow promotion of this favorable condition by targeting the relevant pathways
A protocol for microbiologically safe preparation, storage and use of autologous serum eye-drops
No full textGoing Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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