1,720,965 research outputs found

    L’area metropolitana di Cagliari

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    L'articolo analizza le proposte di definizione dell'area metropolitana cagliaritan

    Papillomatosi recidivante respiratoria. Possibilità della terapia interferonica

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    Obiettivo. La papillomatosi respiratoria recidivante (RRP) è una patologia delle alte e basse vie respiratorie la cui ormai comprovata etiopatogenesi virale per diverso tempo ha costituito materia di studio per molti ricercatori e nel contempo ha rappresentato una sfida per quanto riguarda la programmazione terapeutica, che da sempre ha dovuto fare i conti con la irriducile tendenza alla recidiva di questa affezione. Distinta in due entità cliniche, «juvenile onset» e «adult onset» a seconda dell’età di insorgenza e delle differenti caratteristiche di estrinsecazione clinica, pur potendosi collocare fra le affezioni benigne, essa espone i soggetti affetti ad un vero e proprio calvario terapeutico costituito da interventi chirurgici, spesso ripetuti per la già citata tendenza a recidivare, e da terapie di supporto medico, che a vario titolo e con differenti risultati, tentano di risolvere o perlomeno attenuare il problema costituito dalla inesauribile spinta replicativa virale. Metodi. Gli Autori, sulla base della loro esperienza, propongono uno schema terapeutico basato sull’utilizzo dell’esclusiva terapia interferonica, cui candidare soggetti affetti da RRP a localizzazione laringea con caratteristiche ben definite: diffusione laringea non massiva, tale da non richiedere l’ausilio della tracheotomia, e buone condizioni generali tali da consentire la pratica della terapia interferonica, non sempre scevra da effetti collaterali importanti. Risultati. Lo proposta terapeutica degli Autori, applicata a soggetti affetti da RRP, scelti dopo una valutazione accurata, in prima istanza ha dimostrato di poter perlomeno differire l’utilizzo della terapia chirurgica, consentendo in questo modo di evitare la disseminazione nell’albero respiratorio delle particelle virali indotta sia dall’intubazione che dalla vaporizzazione provocata dal laser. Conclusioni. Lo schema di terapia interferonica per la cura delle lesioni laringee indotte dalla RRP presenta delle indicazioni limitate sia dalle caratteristiche del farmaco, che dal tipo di lesioni da trattare, che devono avere caratteristiche ben precise; presenta altresì indubbi vantaggi rappresentati dalla possibilità di far regredire le lesioni papillomatose, mantenere sotto controllo la spinta replicativa virale, e nel contempo evitare alcune problematiche presentate dalla terapia chirurgica

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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