14,636 research outputs found
Douglas Alexander Stewart, poet, author and playwright
No full textDouglas Alexander Stewart, poet, author and playwrigh
A clinical report highlighting some factors influencing successful vaginal colonization with probiotic Lactobacillus crispatus
No full textAuthor inscription in William Hazlitt, essayist and critic; selections from his writings, with a memoir, biographical and critical by Alexander Ireland
No full textAuthor's gift inscription, "To W. C. Hazlitt Esq with kind regards, from Alexr Ireland," with tipped-in review of the book.ASU Library edition has inscription from Ireland to Hazlitt [a child of William Hazlitt?].
Hazlitt , William, 1778-1830.
Ireland, Alexander, 1810-1894
The Author of the Alexander Romance
No full textThis paper, which is based on a portion of the introduction of the author’s edition of Il Romanzo di Alessandro (Mondadori: Fondazione Valla 2007), surveys the generic components of the Alexander Romance in an attempt to arrive at a definition of the work. The argument builds on Merkelbach’s categorisation of elements and uses Fusillo’s insight into the novel as an ‘encyclopaedic genre’ to propose that ‘historical novel’ is not, as Hägg contended, a misnomer for the work. The main components I discuss are: ‘life’; praxeis; chreiai; Cynic elements, including choliambic poetry and utopian perspectives; and the Egyptian aspects of the narrative. A concluding jeu d’esprit offers a characterisation of the putative author, his antecedents and his process of composition.Richard Stoneman was for 25 years editor for classics at Croom Helm and then Routledge. In 1997 he was appointed an Honorary Fellow in the department of classics, University of Exeter. After retiring from publishing in 2006 he has been pursuing his researches on the Alexander legends and teaching a course on the subject at Exeter. His Penguin translation of the Alexander Romance was published in 1991, and a volume of translated Legends of Alexander the Great appeared from Everyman in 1994. Also in 1994 he co-edited Greek Fiction with John Morgan. His edition of the Greek recensions of the Alexander Romance was published (volume I) by the Fondazione Valla in 2007 – volumes II and III will follow over the next few years – and his Alexander the Great: A Life in Legend appeared from Yale University Press in spring 2008. He is the author of a number of other books on Greek history and travel, and is writing a book on oracles
Author Correction: The dengue-specific immune response and antibody identification with machine learning
No full textCorrection to: npj Vaccineshttps://doi.org/10.1038/s41541-023-00788-7, published online 20 January 2024 In this article, the affiliation details for author Alexander Horst were incorrectly given as Alexander Horst1,2 but should have been Alexander Horst1 and other affiliations are renumbered. The original article has been corrected
Description of the draft genome sequence of Streptococcus salivarius eK12, a derivative of the probiotic strain Streptococcus salivarius K12 with a modified plasmid
No full text: The draft genome of Streptococcus salivarius eK12, a derivative of the strain K12 with a modified plasmid (pRSSL1), is presented. eK12 was engineered to enhance its probiotic properties against S. pyogenes (GAS) by modulating salivabactin production and interfering with a GAS quorum sensing pathway
Use of Streptococcus salivarius K12 in supporting the mucosal immune function of active young subjects: A randomised double-blind study
No full textIntroduction: Upper respiratory tract infections (URTI) are the most common illnesses affecting athletes, causing absences from training and competition. Salivary immunoglobulin A (sIgA) is the main immune factor in saliva, and a consistent association between low concentrations of sIgA and an increased incidence of URTIs has been reported. The oral probiotic Streptococcus salivarius K12 has been suggested to have the potential to improve oral diseases and mucosal barrier function. However, the effects of this probiotic on active young subjects performing a high-intensity training (HIT) program have not been investigated. Methods: Active young students were randomised into a treated group (S. salivarius K12) and a control (placebo) group and asked to take the product daily for 30 days. After this period, participants performed a graded exercise test and five HIT sessions, all within 3 days. They were also asked to complete the Wisconsin Upper Respiratory Symptom Survey daily to monitor URTI's presence. Before and after the 30 days, and at 0h, 24h and 72h after the last training session, saliva samples were collected to quantify sIgA level, secretion rate, and flow. The effect of S. salivarius K12 intake on these parameters was tested using an ANOVA for repeated measures. Results: Twenty (M = 14, F = 6) young subjects (23.5 ± 2.3 years old) participated in the study. The total accumulated training load (sRPE) in the supplementation period was similar in the two groups (treated: 4345 ± 3441 AU; control: 4969 ± 4165 AU; p > 0.05). Considering both sIgA level and secretion rate, significant time (F(4,15) = 3.38; p = 0.037; F(4,15) = 6.00; p = 0.004) and time×group interactions (F(4,15) = 2.49; p = 0.049; F(4,15) = 5.01; p = 0.009) were reported, with the treated group showing higher sIgA levels at 72h post-exercise and increased secretion rate both at 0h and 72h. The number of URTI episodes was similar in the treated and control groups (χ2 = 1.83; p > 0.05). Conclusion: This study demonstrates that relatively short-term S. salivarius K12 supplementation increased sIgA level and secretion in healthy subjects performing a demanding exercise-training programme composed of HIT sessions
Alexander Woollcott, author and stage actor
No full textAlexander Woollcott, author and stage actorTo order a reproduction, inquire about permissions, or for information about prices see:
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Berberine and Dyslipidemia: Different Applications and Biopharmaceutical Formulations Without Statin-Like Molecules—A Meta-Analysis
No full textThe aim of this study was to analyze the efficacy of berberine taken alone or in other formulations (with silymarin or other mixtures) on dyslipidemia through a systematic review of the literature and a meta-analysis. A systematic investigation was conducted on 19 studies that were selected based on inclusion and exclusion criteria. Both controlled trials (n = 12) and cross-sectional trials (n = 7) were included. The following formulations were examined: berberine used alone (n = 5), berberine combined with silymarin (n = 8), and other mixture containing berberine (n = 6). A meta-analysis was performed using a fixed-effects model and meta-regression. Total cholesterol (TC), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and triglycerides were considered. Moreover, possible associations of each parameter with age and the dose and duration of the treatment were analyzed. The data obtained showed a significant reduction in TC and LDL cholesterol for each formulation. A reduction in triglycerides was also observed for both TC and LDL but with a smaller impact. As regards HDL, a slight increase was observed, but it was not statistically significant. The formulation of berberine in association with silymarin was found to have the greatest impact on TC, LDL, HDL, and triglycerides. The greater efficacy of the formulation consisting of berberine associated with silymarin can probably be accounted for by the fact that the latter increases the bioavailability of berberine. However, it is necessary to carry out further clinical studies to better define the efficacy of the treatment and which patients show the best response
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