1,721,026 research outputs found
CHROMATOGRAPHIC CHARACTERIZATION OF ENDOGENOUS DIGOXIN-LIKE IMMUNOREACTIVE SUBSTANCES PRESENT IN SERUM AND URINE OF INFANTS USING GEL-FILTRATION WITH SEPHADEX G-25
No full textThe specific 3H-ouabain binding to Na+/K+-ATPase of the human placental tissue is inhibited by newborn plasma extracts.
No full textCharcoal-based products combustion: Emission profiles, health exposure, and mitigation strategies
Full text linkCharcoal-based products are widely spread and appreciated as fuel for grilling food. However, during their use, they release high emissions that pose significant environmental issues and health risks. Charcoal grilling emissions contain a wide range of pollutants including CO, CO2, NOx, PM, PAHs, VOCs, and trace metals. The emission of these pollutants contributes to both indoor and outdoor air pollution. Factors such as charcoal type and qualitative characteristics, combustion temperature, and the presence of food influence the emission released. Compared to domestic emissions, charcoal grilling restaurants can be a major source of air pollutants affecting both indoor and outdoor air quality. The deterioration of air quality determines health repercussions. This study aimed to review the existing scientific literature on the environmental and health implications of charcoal-based products used in domestic and restaurant settings. The association between charcoal grilling emissions, respiratory illnesses, cardiovascular diseases, and the increased risk of developing carcinogenic conditions was evaluated. Workers in restaurant settings, exposed to cooking fumes for several hours, are particularly vulnerable to these health risks, but even short exposure can lead to health problems. Mitigation strategies involve different approaches, including the use of high-quality charcoal, implementing a certification system to ensure high-quality tested products, using grilling equipment designed to reduce emissions, ensuring proper ventilation, using abatement systems, and promoting responsible and sustainable grilling practices. Implementing these strategies guarantees more eco-friendly and safer grilling conditions while effectively reducing the adverse impacts of charcoal combustion on the environment and human health
Selective inhibition of human erythrocyte Na+/K+ ATPase by cardiac glycosides and by a mammalian digitalis like factor
No full textNa+/K(+)ATPase is a transport membrane protein which contains the functional receptor for digitalis compounds, In this work we compare the inhibition curves of Na+/K(+)ATPase measured by the inhibition of Rb-86 uptake in human red blood cells by cardiac glycosides and by an endogenous digitalis like factor (EDLF) extracted from human newborn cord blood. The curves of Na+/K(+)TPase inhibition show a monophasic shape for ouabain, strophantidin, digitoxin, proscillaridin and EDLF whereas a biphasic shape for ouabagenin, digoxin, digoxigenin and digitoxigenin. All the drugs are potent inhibitors of erythrocyte Na+/K(+)ATPase with an IC50 ranging from 1.8x10(-9)M to 1.4x10(-11)M for the higher affinity binding site and from 1.8X10(-6)M to 5.5X10(-9)M for the lower affinity site. Digitoxigenin is the most active showing the higher active site at 1.4X10(-11)M. Ouabain and digoxin have higher affinity compared with their corresponding genins, while digitoxigenin shows a binding site with higher affinity than the respective cardiac glycosides, The increased affinity of the drugs to Na+/K(+)ATPase may be related to a lipophilic region in correspondence of the carbons 10, 9, 11, 12, 13 of the steroid nucleus, situated in the opposite side with respect of the C-OH-14. The comparison of the inhibition curves and the HPLC profile of newborn EDLF and of the investigated cardenolides suggest that EDLF may be a compound identical or very similar to ouabain. (C) 2000 Elsevier Science Inc. All rights reserved
Indagine sulla composizione del tessuto muscolare di chiocciole terrestri appartenenti al genere Helix
No full textFurther evidence for an endogenous digitalis-like compound in newborn and adult plasma detected by anti-ouaboin antiserum
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Cuttlefish Species Authentication: Advancing Label Control through Near-Infrared Spectroscopy as Rapid, Eco-Friendly, and Robust Approach
Full text linkAccurate species identification, especially in the fishery sector, is critical for ensuring food safety, consumer protection and to prevent economic losses. In this study, a total of 93 individual frozen-thawed cuttlefish samples from four different species (S. officinalis, S. bertheloti, S. aculeata, and Sepiella inermis) were collected from two wholesale fish plants in Chioggia, Italy. Species identification was carried out by inspection through morphological features using dichotomic keys and then through near-infrared spectroscopy (NIRS) measurements. The NIRS data were collected using a handled-portable spectrophotometer, and the spectral range scanned was from 900-1680 nm. The collected spectra were processed using principal component analysis for unsupervised analysis and a support vector machine for supervised analysis to evaluate the species identification capability. The results showed that NIRS classification had a high overall accuracy of 93% in identifying the cuttlefish species. This finding highlights the robustness and effectiveness of spectral analysis as a tool for species identification, even in complex spatial contexts. The findings emphasize the potential of NIRS as a valuable tool in the field of fishery product authentication, offering a rapid and eco-friendly approach to species identification in the post-processing stages
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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